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抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
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Angiogenesis
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Cytoskeletal Signaling
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Anti-infection
Proteases
Immunology & Inflammation
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others
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Deuterated
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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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On Sale
中间体
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联系我们
公司简介
联系我们
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产品名字索引 D
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产品名字索引 D
Deutivacaftor
(Catalog# : 24096, Cas# :
1413431-07-8
)
Deutivacaftor, also known as CTP-656 and VX561, is a cystic fibrosis transmembrane co
5-氘代-2,4-二溴噻唑
(Catalog# : 24060, Cas# :
960069-34-5
)
Denifanstat
(Catalog# : 20596, Cas# :
1399177-37-7
)
TVB-2640 is an orally bioavailable fatty acid synthase (FASN) inhibitor, with potenti
1,1-Dimethylethyl (1S,5S)-1-formyl-3-azabicyclo[3.1.0]hexane-3-carboxylate
(Catalog# : 20545, Cas# :
1932352-50-5
)
1,1-Dimethylethyl (1R,5S)-1-ethynyl-3-azabicyclo[3.1.0]hexane-3-carboxylate
(Catalog# : 20544, Cas# :
1932410-93-9
)
(1S,5S)-1-(羟甲基)-3-氮杂双环[3.1.0]己烷-3-羧酸叔丁酯
(Catalog# : 20543, Cas# :
1932534-25-2
)
Danuglipron
(Catalog# : 20538, Cas# :
2230198-02-2
)
Danuglipron, also known as PF-06882961 is a potent, orally bioavailable agonist of th
4,5-二碘-2-甲基-1,2,3三氮唑
(Catalog# : 20520, Cas# :
859790-39-9
)
DSN28369
(Catalog# : 20498, Cas# :
2413428-36-9
)
DSN28369 is a heterobifunctional linker, and useful to make antibody drug conjuate (A
DSR-6434
(Catalog# : 20497, Cas# :
1059070-10-8
)
DSR-6434 is a potent TLR7 agonist (EC50 = 7.2 nM). DSR-6434 activates several immune
DASA-58
(Catalog# : 20489, Cas# :
1203494-49-8
)
DASa-58, also known as ML-203 and NCGC00185916, is a selective activator of pyruvate
DC-S100
(Catalog# : 20456, Cas# :
178803-91-3
)
DC-S100 is a selective histone methyltransferase SET7 inhibitor.
4,5-二氯吲哚
(Catalog# : 20442, Cas# :
122509-73-3
)
Deruxtecan
(Catalog# : 20437, Cas# :
1599440-13-7
)
Deruxtecan, a topoisomerase I inhibitor, is an exatecan derivative (DX-8951 derivativ
4,6-二氯-1H-吡唑并[3,4-B]吡啶
(Catalog# : 20434, Cas# :
2105905-46-0
)
2,5-二氨基-2,5-环己二烯-1,4-二酮
(Catalog# : 171654, Cas# :
1521-06-8
)
2,6-DIFLUORO-4-[2-(PHENYLSULFONYLAMINO)E
(Catalog# : G20379, Cas# :
141286-78-4
)
4,6-dimethylpyrazolo[1,5-a]pyrazine-2-carbaldehyde
(Catalog# : 20361, Cas# :
2407725-14-6
)
Diphenylterazine
(Catalog# : 20324, Cas# :
344940-63-2
)
Diphenylterazine is a bioluminescence agent. Diphenylterazine alone yields very littl
DDD100097
(Catalog# : 20307, Cas# :
1215012-74-0
)
DDD100097 is an inhibitor of Trypanosoma brucei N-myristoyltransferase (TbNMT) with m
Dimethyl carbate
(Catalog# : 20274, Cas# :
39589-98-5
)
Dimethyl carbate is an insect repellent. It can be prepared by the Diels–Alder reac
Delgocitinib(JTE-052)
(Catalog# : 20273, Cas# :
1263774-59-9
)
Delgocitinib,也称为 LEO-124249 和 JTE052,是一种有效的选择性 JAK 抑制
Dapaconazole
(Catalog# : 20272, Cas# :
1269726-67-1
)
Dapaconazole is an antifungal drug candidate. Phase II trials showed that Dapaconazol
Difelikefalin 盐酸盐
(Catalog# : 21922, Cas# :
2413256-25-2
)
Difelikefalin, also known CR-845; MR-13A-9; MR-13A9, is a novel and potent kappa opio
Daridorexant ( ACT541468 )
(Catalog# : 20265, Cas# :
1505484-82-1
)
Daridorexant 是一种双重食欲素受体拮抗剂 (DORA),专为治疗失眠而设
Difelikefalin
(Catalog# : 21257, Cas# :
1024828-77-0
)
Difelikefalin HCl is in stock.Difelikefalin, also known CR-845; MR-13A-9; MR-13A9, is
2,4-二甲氧基-6-甲基烟腈
(Catalog# : 21255, Cas# :
1450662-05-1
)
2,4-二甲氧基-6-甲基烟腈, is a key intermediate ofLirametostat ( CPI-1205 ).Bu
DTHIB
(Catalog# : 21242, Cas# :
897326-30-6
)
DTHIB is a direct and selective heat shock factor 1 (HSF1) inhibitor with a Kd of 160
diABZI STING agonist-1 trihydrochloride
(Catalog# : 2112802, Cas# :
2138299-34-8
)
DS-6051B adipate
(Catalog# : 211153, Cas# :
1505515-69-4
)
DS-6051B is an orally available inhibitor of the receptor tyrosine kinases C-ros onco
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag