武汉永璨生物科技有限公司
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抑制剂/受体激动剂
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Cytoskeletal Signaling
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others
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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
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Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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On Sale
中间体
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定制合成
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订购信息
联系我们
公司简介
联系我们
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产品名字索引 J
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产品名字索引 J
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
JTE-151
(Catalog# : 20594, Cas# :
1404380-58-0
)
JNJ-54175446
(Catalog# : 20534, Cas# :
1627902-21-9
)
JNJ-54175446 is a potent and selective P2X7 Receptor Antagonist. JNJ-54175446 is pote
JC124
(Catalog# : 20495, Cas# :
1638611-48-9
)
JC124 is a NLRP3 Inflammasome Inhibitor.
JTE-607 HCl
(Catalog# : 20479, Cas# :
188791-09-5
)
JTE-607, also known as TO-207, is a cytokine production inhibitor potentially for the
JTE-051
(Catalog# : 20458, Cas# :
1309784-09-5
)
JTE-051 is a novel inhibitor of interleukin-2-inducible T cell kinase (ITK), suppress
JQKD82
(Catalog# : 20285, Cas# :
2410512-38-6
)
JQKD82 is a cell-permeable and selective KDM5 inhibitor (MM.1S cells, IC50 = 0.42 uM)
JNJ-63576253
(Catalog# : 21250, Cas# :
2110426-27-0
)
TRC253, also known as JNJ63576253, is a potent and orally active androgen receptor an
JUN90152
(Catalog# : 21247, Cas# :
2098890-15-2
)
JUN90152, also known as SMS2-IN-1, is a potent and highly selective sphingomyelin syn
JND3229
(Catalog# : 2091904, Cas# :
2260886-64-2
)
JND3229 is a New EGFRC797S Mutant Inhibitor with In Vivo Monodrug Efficacy (IC50 = 5.
JMS-17-2
(Catalog# : 2071624, Cas# :
1380392-05-1
)
JMS-17-2 is a potent and selective antagonist of CX3CR1.
JAK3-IN-2
(Catalog# : 2071551, Cas# :
1443235-95-7
)
JAK3-IN-2 is a potent and highly selective JAK3 inhibitor.
JI051
(Catalog# : 2071526, Cas# :
2234281-75-3
)
JI051 is an inhibitor of the cancer-associated transcription factor Hes1 via the PHB2
JNJ-632
(Catalog# : 2071507, Cas# :
1572510-42-9
)
JNJ-632 is a potent HVV capsid assembly modulator and HBV replication inhibitor with
JNK-IN-7
(Catalog# : 2061305, Cas# :
1408064-71-0
)
JNK-IN-7 is a relatively selective JNKs inhibitor(IC50= 1.54/1.99/0.75 for JNK1/2/3);
JNK-IN-7
(Catalog# : 2061305, Cas# :
1408064-71-0
)
JNJ-38877618
(Catalog# : 204307, Cas# :
943540-74-7
)
JNJ-38877618 is a hepatocyte growth factor receptor (HGFR; MET; c-Met) inhibitor pote
JNJ-64619178
(Catalog# : 193292, Cas# :
2086772-26-9
)
JNJ-64619178是一种候选的抗癌药物。
JNJ0966
(Catalog# : 193201, Cas# :
315705-75-0
)
JNJ0966是一种高选择性的基质金属蛋白酶-9 (MMP-9)变构抑制剂。
JTE-013
(Catalog# : 184313, Cas# :
383150-41-2
)
TE-013是一种有效、选择的鞘氨醇-1-磷酸2 (S1P2)受体拮抗剂,分别与
JPH203 HCl ( Nanvuranlat )
(Catalog# : 18381, Cas# :
1597402-27-1
)
JPH203,也称为KYT- 0353,是一个强有力的和选择性(l型氨基酸转运蛋白
JNJ-40346527
(Catalog# : 1711221, Cas# :
1142363-52-7
)
JNJ-40346527是一种小分子和口服抑制剂,可用于促结肠菌素- 1受体(
JNJ-42153605
(Catalog# : 1791311, Cas# :
1254977-87-1
)
JNJ-42153605是一种强效的选择性mGlu2受体PAM可接受的药代动力学在啮
JNJ-42165279(2HCl salt)
(Catalog# : 1783012, Cas# :
1346528-51-5
)
JNJ-42165279具有良好的ADME和药效学特性,可以证明其在大鼠的大脑
JNJ-42165279(mono HCl salt)
(Catalog# : 1783011, Cas# :
1346528-52-6
)
JNJ-42165279(mono HCl salt)是一种强力的选择性脂肪酸酰胺水解酶(FAAH)抑
JQ-EZ-05
(Catalog# : 2017871, Cas# :
1913252-04-6
)
JQ-EZ-05也称为JQEZ5, 是一种生物活性化学药品。
JNK-IN-8
(Catalog# : 16123027, Cas# :
1410880-22-6
)
JNK-IN-8, also known as JNK Inhibitor XVI, is a selective JNK inhibitor that inhibits
JNJ 63533054
(Catalog# : 16123026, Cas# :
1802326-66-4
)
JNJ 63533054 is a potent and selective GPR139 agonist (EC50 = 16 nM) that is brain an
JNJ-42165279
(Catalog# : 16123025, Cas# :
1346528-50-4
)
JNJ-42165279 is a potent and selective fatty acid amide hydrolase (FAAH) inhibitor. J
JI-101
(Catalog# : 16122823, Cas# :
900573-88-8
)
JI-101 is an orally active inhibitor of vascular endothelial growth factor receptor 2
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag