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抑制剂/受体激动剂
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others
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分子砌块
Aldehydes
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Amino Acids
Anilines
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Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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On Sale
中间体
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订购信息
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公司简介
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产品名字索引 D
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产品名字索引 D
dBET1
(Catalog# : 186261, Cas# :
1799711-21-9
)
dBET1是BET bromodomains的竞争性拮抗剂,其目的是劫持Cereblon E3泛素连
2-D08
(Catalog# : 186231, Cas# :
144707-18-6
)
2-D08是一种合成黄酮类物质,可以抑制类间酰化。2-D08显示抗聚集
柔红霉素
(Catalog# : 186212, Cas# :
20830-81-3
)
柔红霉素通过拓扑异构酶介导与DNA的相互作用来表现细胞毒性,从
DEL-22379
(Catalog# : 186155, Cas# :
181223-80-3
)
DEL-22379是一种有效的选择性二聚反应抑制剂。
德拉沙星
(Catalog# : 18612, Cas# :
189279-58-1
)
德拉沙星,也被称为ABT-492, RX-3341和WQ-3034,是一种非锌离子氟喹诺
Delpazolid
(Catalog# : 18611, Cas# :
1219707-39-7
)
Delpazolid,又称LCB01-0371,是一种新型的环胺唑酮恶唑啉酮。
Desidustat
(Catalog# : 185231, Cas# :
1616690-16-4
)
Desidustat是一种抗贫血药。
多韦替尼乳酸盐
(Catalog# : 18575, Cas# :
915769-50-5
)
多韦替尼,也称为TKI-258或CHIR-258,是一种口服生物药效应的FGFR3抑制
Defensamide
(Catalog# : 184212, Cas# :
1104874-94-3
)
Defensamide, also known as MHP and methyl caprooyl tyrosinate, is an activator of sph
2-(4-(((2,4-dimethylbenzoyl)oxy)methyl)phenyl)acetic acid
(Catalog# : 183215, Cas# :
2097334-16-0
)
2-(4-(((2,4-dimethylbenzoyl)oxy)methyl)phenyl)acetic acid is a drug intermediate.
DCG04
(Catalog# : 179813, Cas# :
314263-42-8
)
DCG04是一种多价配体针对甘露糖-6-磷酸受体中基于活动的探针定位
3,5-Dichloro-N-[(1,1-dimethylethoxy)carbonyl]-L-tyrosine methyl ester
(Catalog# : 178222, Cas# :
261926-09-4
)
<span style="color:#333333;font-family:"font-size:14px;background-color:
2,6-二溴苄腈
(Catalog# : 1781502, Cas# :
67197-53-9
)
2-(2,6-dibroMophenyl)acetonitrile 是有机合成反应中的一个重要合成砌块
达鲁舍替
(Catalog# : 1781107, Cas# :
827318-97-8
)
达鲁舍替,也称为PHA-739358,是一种小分子3 -氨基吡唑衍生物,具
6-(4,5-dihydro-1H-imidazol-2-yl)-2-methoxy-3-[3-(morpholin-4-yl)propoxy]aniline
(Catalog# : 2017080116, Cas# :
1032571-01-9
)
6-(4,5-dihydro-1H-imidazol-2-yl)-2-methoxy-3-(3-morpholin-4-ylpropoxy)aniline
多巴酚丁胺盐酸盐
(Catalog# : 17030803, Cas# :
49745-95-1
)
多巴酚丁胺是一种交感神经药物,用于治疗心力衰竭和心源性休克
Defactinib
(Catalog# : 120111, Cas# :
1073154-85-4
)
Defactinib是一种有效的FAK磷酸化抑制剂;通过依赖AKT的途径克服抵抗
环酯红霉素
(Catalog# : 17030310, Cas# :
55224-05-0
)
环酯红霉素, 又称红霉素环碳酸盐,是一种由链霉素产生的抑菌抗
丹参素
(Catalog# : 17021315, Cas# :
76822-21-4
)
丹参素,一种中药制剂,具有潜在的抗肿瘤和抗血管生成作用。
2,3-dimethyl-2,5-cyclohexadiene-1,4 dione
(Catalog# : 17011908, Cas# :
526-86-3
)
2,5-Cyclohexadiene-1,4-dione,2,3-dimethyl-
4,5-Dihydro-2-(Methylthio)-1H-iMidazole-1-carboxylic Acid Methyl Ester
(Catalog# : 17011907, Cas# :
60546-77-2
)
It is a new drug
Doxapram
(Catalog# : 16122937, Cas# :
309-29-5
)
Doxapram is a respiratory stimulant. Administered intravenously, doxapram stimulates
Dobutamine HCl
(Catalog# : 16122936, Cas# :
34368-04-2
)
Dobutamine is a sympathomimetic drug used in the treatment of heart failure and cardi
DM1-SMe
(Catalog# : 16122935, Cas# :
138148-68-2
)
DM1-SMe is a potent maytansinoid microtubular inhibitor and an unconjugated DM1 as a
DM1-SMCC
(Catalog# : 16122934, Cas# :
1228105-51-8
)
DM1-SMCC is DM1 with a reactive linker SMCC, which can react with antibody to make an
Dimethylenastron
(Catalog# : 16122932, Cas# :
863774-58-7
)
Dimethylenastron is an inhibitor of mitotic motor kinesin Eg5 (IC50 = 200 nM). Dimeth
Dihydroethidium
(Catalog# : 16122931, Cas# :
104821-25-2
)
Dihydroethidium, also known as Hydroethidine and PD-MY 003, is a cell-permeable blue
Delamanid (OPC-67683)
(Catalog# : 16122930, Cas# :
681492-22-8
)
Delamanid, also known as OPC-67683, is a drug for the treatment of multi-drug-resista
Defactinib
(Catalog# : 16122929, Cas# :
1073160-26-5
)
Defactinib, also known as VS-6063 and PF04554878, is an orally bioavailable, small-mo
Debio-1347
(Catalog# : 16122928, Cas# :
1265229-25-1
)
Debio-1347, also known as FF284 and CH5183284, is an orally bioavailable inhibitor of
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag