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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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others
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Cas Index 6
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Cas Index 6
65646-68-6 | Fenretinide
(Catalog# : 52226)
Fenretinide (4-HPR) is a synthetic retinoid deriverative. 4-HBR is shown to exhibit b
611168-24-2 | Glycerol phenylbutyrate ( HPN-100 )
(Catalog# : 230401)
Glycerol phenylbutyrate, also known as HPN-100, is under trials in the treatment of c
660868-91-7 | GW843682X
(Catalog# : 185292)
GW843682X is a selective inhibitor of polo-like kinase 1 (PLK1) and polo-like kinase
6823-69-4 | GW4869
(Catalog# : 178912)
GW4869 (dihydrochloride hydrate) is a cell permeable, selective inhibitor of N-SMase
67469-57-2 | GBR 12783
(Catalog# : 16071019)
GBR 12783
67469-81-2 | GBR 12935 dihydrochloride
(Catalog# : 52404)
GBR 12935 2Hcl is a potent, and selective dopamine reuptake inhibitor.
651744-48-8 | 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-1-[tris(1-methylethyl)silyl]-
(Catalog# : 20410)
62803-47-8 | 6-Hydroxy-1-indanone
(Catalog# : 81930)
Coming soon!
670270-31-2 | IU1-47
(Catalog# : 181025)
IU1-47 is a potent and selective inhibitor of USP14.
662163-81-7 | Importazole
(Catalog# : 17031013)
Importazole is a small molecule inhibitor of the transport receptor importin- speci
610798-31-7 | Icotinib
(Catalog# : 011101)
Icotinib is an orally available quinazoline-based inhibitor of epidermal growth facto
687561-60-0 | IWP-3
(Catalog# : 010801)
IWP-3 is an inhibitor of Wnt production.
686770-61-6 | IWP-2
(Catalog# : 110602)
IWP-2 is an inhibitor of Wnt secretion and processing. It blocks Wnt-dependent signal
68034-75-3 | 3-(3-Iodophenyl)propanoic acid
(Catalog# : 90712)
Coming soon!
600734-06-3 | KINK-1
(Catalog# : 192152)
KINK-1 is an inhibitor of IKKß, blocking NF-kappaB activation.
672926-33-9 | Kif15-IN-2
(Catalog# : 611942)
Kif15-IN-2 is a potent Kif15 kinesin inhibitor; inhibits cellular proliferation in tu
672926-32-8 | Kif15-IN-1
(Catalog# : 611941)
Kif15-IN-1 is a potent Kif15 kinesin inhibitor; inhibits cellular proliferation in tu
65277-42-1 | Ketoconazole
(Catalog# : 122525)
Ketoconazole is an imidazole anti-fungal agent, a CYP3A4 inhibitor.
66592-89-0 | Kevetrin HCl
(Catalog# : 111002)
Kevetrin hydrochloride is a small molecule and activator of the tumor suppressor prot
664969-54-4 | LF3
(Catalog# : 1710164)
LF3 is a specific inhibitor of the classical Wnt signaling pathway by disrupting the
613677-28-4 | Lasmiditan hydrochloride
(Catalog# : 6111005)
Lasmiditan (COL-144; LY573144) is a high-affinity, highly selective 5-HT1F receptor a
603288-22-8 | LY2090314
(Catalog# : 5121102)
LY2090314 (LY) is a glycogen synthase kinase 3 inhibitor with preclinical efficacy in
668467-91-2 | LDN-57444
(Catalog# : 110606)
LDN-57444 is a Uch-L1 inhibitor with Ki= 0.4 M. Ubiquitin carboxy-terminal hydrolase
64232-83-3 | L189
(Catalog# : 91001)
L189 inhibits base excision repair (BER) and non-homologous end joining (NHEJ), which
668270-12-0 | Linagliptin
(Catalog# : 82608)
Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM.
639052-78-1 | LH846
(Catalog# : 51504)
LH846 is a selective inhibitor of CK1 (IC50 values are 290 nM, 1.3 uM and 2.5 uM for
69120-06-5 | Moracin C
(Catalog# : 20466)
Moracin C is a phenolic compound isolated from Artocarpus heterophyllus. Moracin C su
624733-88-6 | MK-0812
(Catalog# : 2017080111)
MK-0812 is a potent and selective CCR2 antagonist. Chemokine (C-C motif) receptor 2 (
653592-04-2 | MT-DADMe-ImmA
(Catalog# : 703301)
Methylthio-DADMe-immucillin-A (MT-DADMe-ImmA) is an 86-pm inhibitor of human 5-methyl
65271-80-9 | Mitoxantrone HCl
(Catalog# : 16123051)
Mitoxantrone hydrochloride is the hydrochloride salt of an anthracenedione antibiotic
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
3034479-99-4 | HC-5404
(Catalog# : 24112)
HC-5404 is a novel, highly selective and potent PERK inhibitor.
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno