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Catalysts
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Indoles and Oxindoles
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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
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Piperidines
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Pyrimidines
Quinolines
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Thiazoles
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联系我们
公司简介
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产品名字索引 A
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产品名字索引 A
AVN-492
(Catalog# : 18425, Cas# :
1220646-23-0
)
AVN-492是一种有效且具有选择性的5-HT6R拮抗剂。AVN-492具有良好的体
ALB-127158A
(Catalog# : 18424, Cas# :
1173154-32-9
)
ALB-127158A, also known as ALB-127158(a), is a MCH1 antagonist for the treatment of o
AZD-5904
(Catalog# : 181121, Cas# :
618913-30-7
)
AZD5904是一个有效的口服生物利用率MPO抑制剂。在临床前研究中,AZ
2-氨基嘧啶-5-羧酸
(Catalog# : 171281, Cas# :
3167-50-8
)
2-氨基嘧啶-5-羧酸
Asciminib ( ABL001 )
(Catalog# : 1711222, Cas# :
1492952-76-7
)
Asciminib, 也叫ABL001,是一种有效的BCR-ABL的变构抑制剂。ABL001在与尼
Autophinib
(Catalog# : 17101617, Cas# :
1644443-47-9
)
Autophinib是一种新颖有效的自噬抑制剂,抑制通过靶向脂质激酶VPS
Adarigiline
(Catalog# : 1710167, Cas# :
1124197-79-0
)
adarigiline是单胺氧化酶B抑制剂的候选药物。
Adafosbuvir
(Catalog# : 1710166, Cas# :
1613589-09-5
)
Adafosbuvir是一种抗病毒药物。
AZD-5153 HNT salt
(Catalog# : 1710161, Cas# :
1869912-40-2
)
AZD-5153 HNT盐,是AZD-5153的6-hydroxy-2-naphthoic酸盐。AZD-5153对抗血液系
ABT-100
(Catalog# : 1710131, Cas# :
450839-40-4
)
abt-100是一种口服的法尼基转移酶抑制剂.
阿西鲁司特
(Catalog# : 179159, Cas# :
943764-99-6
)
阿西鲁司特,也称为ZK322,是强有力的和有选择性的白三烯A4水解酶
AR-7
(Catalog# : 179158, Cas# :
80306-38-3
)
AR-7,亦称非典型维甲酸7,是一种有效的和选择性的自噬(CMA)增
阿地米屈
(Catalog# : 179151, Cas# :
1675-66-7
)
阿地米屈是壬二酸的合成酰胺衍生物,具有对称的化学结构。它被
AZD7545
(Catalog# : 179136, Cas# :
252017-04-2
)
AZD7545是丙酮酸脱氢酶激酶2抑制剂(pdhk2)(对6.4nm IC50值)用于治
AMG-9810
(Catalog# : 179117, Cas# :
545395-94-6
)
AMG 9810是对香草类受体1的辣椒素激活竞争性拮抗剂(TRPV1)。此外
AS-2444697 HCl
(Catalog# : 179832, Cas# :
1287665-60-4
)
AS-2444697是一种 RAK-4抑制剂。六周重复给药AS2444697(0.3-3mg/kg,一天
乙酰卡尼盐酸盐
(Catalog# : 179829, Cas# :
34118-92-8
)
乙酰卡尼,又名N-乙酰普鲁卡因胺和ASL 601,普鲁卡因胺是N-乙酰化
ASC-J9
(Catalog# : 179816, Cas# :
52328-98-0
)
ASC-J9,也称为GO-Y025和去甲氧基姜黄素,是一个AR降解剂,ASC-J9通过
AMG-009
(Catalog# : 17987, Cas# :
1027847-67-1
)
AMG 009是一种口服活性小分子CRTH2受体(趋化受体的同源分子表达在
5-氨基-2-氟-4-甲基苯腈
(Catalog# : 1781603, Cas# :
1426136-04-0
)
5-氨基-2-氟-4-甲基苯腈,5-amino-2-fluoro-4-methylbenzonitrile
2-azaspiro[3.5]nonan-7-ol hydrochloride
(Catalog# : 1781602, Cas# :
1434141-67-9
)
2-azaspiro[3.5]nonan-7-ol hydrochloride
Abemaciclib ( LY2835219)
(Catalog# : 178141, Cas# :
1231929-97-7
)
Abemaciclib,也被称为LY2835219,可口服细胞周期依赖性激酶(CDK)抑制
AZD3264
(Catalog# : 178910, Cas# :
1609281-86-8
)
AZD3264是一种新型的小分子IKK2抑制剂。IKK2作为IB激酶的蛋白质亚基
A-971432
(Catalog# : 178816, Cas# :
1240308-45-5
)
A - 971432对S1P5具有高度选择性,在临床前口服剂量后,显露出良好
A-1165442
(Catalog# : 20178812, Cas# :
1221443-94-2
)
A-1165442是一种中性温度具有止痛功效的瞬时受体电位香草酸亚型1
AZD4205
(Catalog# : 20178710, Cas# :
2091134-35-7
)
AZD4205是一种高效JAK1-选择性激酶抑制剂,拥有优秀的临床前药代动
ACY-775
(Catalog# : 77821, Cas# :
1375466-18-4
)
ACY-775是一种组蛋白去乙酰化酶6(HDAC6)选择性抑制剂。
AAI-101
(Catalog# : 1773101, Cas# :
1001404-83-6
)
AAI101(AAI101)是一种新型的增谱-乳酸酶抑制剂。AAI101(AAI101)与头孢吡
AV-412甲苯磺酸盐
(Catalog# : 17030105, Cas# :
451493-31-5
)
AV-412,也称为MP-412,是第二代生物可利用的双激酶抑制剂,具有潜在
AZD-7594
(Catalog# : 17022812, Cas# :
1196509-60-0
)
AZD-7594,也叫AZ13189620,是一种吸入选择性糖皮质激素受体(GCCR)调制
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag