武汉永璨生物科技有限公司
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抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
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技术服务
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订购信息
联系我们
公司简介
联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 A
按首字母搜索
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产品名字索引 A
A2793
(Catalog# : 20286, Cas# :
88349-90-0
)
A2793 is an inhibitor of TRESK (IC50 value of 6.8 μM for mTRESK). A2793 inhibited TW
ABT-384
(Catalog# : 20281, Cas# :
868623-40-9
)
ABT-384 是 11β-羟基类固醇脱氢酶 1 (HSD-1) 的有效选择性抑制剂,该
AN 0128
(Catalog# : 20269, Cas# :
872044-70-7
)
AN 0128, also known as CRM-0005 and ONT-0001, is a tumour necrosis factor alpha (TNF-
Almonertinib
(Catalog# : 20267, Cas# :
1899921-05-1
)
Almonertinib is an orally available inhibitor of the epidermal growth factor receptor
ALC-0315
(Catalog# : 20264, Cas# :
2036272-55-4
)
ALC-0315 is a synthetic cationic lipid (or ionizable lipid). It is a colorless oily m
AP1189 acetate
(Catalog# : 2105071, Cas# :
959850-74-9
)
AP1189 is a melanocortin receptor agonist on MC1 and MC3 receptors.
AMG-221
(Catalog# : 21223, Cas# :
1095565-81-3
)
AMG-221, BVT-83370, is a potent and selective 11β-HSD1 inhibitor. AMG-221 decreased
ACT-389949 (ACT389949)
(Catalog# : 20211801, Cas# :
1258417-54-7
)
ACT-389949 is a potent and selective agonist of formyl peptide receptor type 2 (FPR2)
AT-56
(Catalog# : 20111201, Cas# :
162640-98-4
)
AT-56 is a selective, competitive, and highly bioavailable inhibitor of lipocalin-typ
ASN007
(Catalog# : 20103001, Cas# :
2055597-12-9
)
ASN007 , a novel oral ERK inhibitor , has shown anti-tumor activity in both solid tum
AB-680
(Catalog# : 2091501, Cas# :
2105904-82-1
)
AB-680一种是高效、可逆和选择性CD73抑制剂。AB-680是第一个临床使
Apilimod mesylate ( STA-5326 )
(Catalog# : 23948, Cas# :
870087-36-8
)
Apilimod, also known as STA-5326, is a potent IL-12/IL-23 inhibitor. Apilimod inhibit
AVN-101 HCl
(Catalog# : 2071801, Cas# :
1061354-48-0
)
AVN-101是一种非常有效的5-HT7受体拮抗剂(Ki = 153 pM),对5-HT6、5-H
APX-115 freebase
(Catalog# : 2071628, Cas# :
1270084-92-8
)
Apcin
(Catalog# : 2071626, Cas# :
300815-04-7
)
Apcin is an inhibitor of the anaphase-promoting complex/cyclosome (APC/C). It acts by
Astemizole
(Catalog# : 2071552, Cas# :
68844-77-9
)
Astemizole is a histamine H1-receptor antagonist. Astemizole competitively binds to h
ARV-771
(Catalog# : 2071539, Cas# :
1949837-12-0
)
ARV-771 is a small-molecule pan-BET degrader. ARV-771 demonstrates dramatically impro
AZD-7648
(Catalog# : 2071531, Cas# :
2230820-11-6
)
AZD-7648 is a potent and selective DNA-PK inhibitor.
AWZ1066S
(Catalog# : 2071530, Cas# :
239272-16-1
)
AWZ1066S is a highly specific anti-Wolbachia drug candidate for a short-course treatm
AER-271
(Catalog# : 2071523, Cas# :
634913-39-6
)
AER-271 is a potent aquaporin-4 (AQP4) inhibitor. AER-271 blocks acute cerebral edema
ABX-1431
(Catalog# : 2071517, Cas# :
1446817-84-0
)
ABX-1431 is a covalent, irreversible MGLL inhibitor. ABX-1431 is currently entering c
AZ31
(Catalog# : 2071508, Cas# :
2088113-98-6
)
AZ31 is a potent and highly selective ATM inhibitor.
AB-423
(Catalog# : 2071503, Cas# :
1572510-80-5
)
AB-423 is a novel inhibitor of hepatitis b virus pregenomic rna encapsidation
2-aminopyrazolo[1,5-a]pyridine-3-carboxylic acid
(Catalog# : 202323, Cas# :
1542020-25-6
)
1-acetyl-5-nitro-3H-indol-2-one
(Catalog# : 2062319, Cas# :
114985-63-6
)
1-acetyl-5-amino-2-indolinone
(Catalog# : 2061313, Cas# :
422518-10-3
)
(4aS,9bR)-Ethyl 6-bromo-5-(2-(methylamino)-2-oxoethyl)-3,4,4a,5-tetrahydro-1H-pyrido[4,3-b]indole-2(9bH)-carboxylate
(Catalog# : 2062312, Cas# :
2098497-32-4
)
8-Acetyl-5-(benzyloxy)-2H-benzo[b][1,4]oxazin-3(4H)-one
(Catalog# : 2062311, Cas# :
1035299-32-3
)
2-Amino-5-cyanopyrazine
(Catalog# : 2062307, Cas# :
113305-94-5
)
5-amino-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxylic acid
(Catalog# : 2062025, Cas# :
1452226-14-0
)
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag