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抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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others
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Antibody-drug Conjugate/ADC Related
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Aldehydes
Amines
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Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
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Peg Linkers
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联系我们
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 A
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产品名字索引 A
Ablukast
(Catalog# : 20319, Cas# :
96566-25-5 (free acid)
)
Ablukast is a leuktriene receptor antagonist that acts as an anti-asthmatic.
2-氨基-5-三氟甲基苯甲酸
(Catalog# : 20312, Cas# :
83265-53-6
)
Afabicin
(Catalog# : 20303, Cas# :
1518800-35-5
)
Afabicin (formerly Debio 1450, AFN-1720) is a prodrug of afabicin desphosphono, an en
Acoramidis (AG-10 )
(Catalog# : 20300, Cas# :
1446711-81-4
)
Acoramidis (formerly AG10) is an investigational, orally-administered small molecule
ASTX-029
(Catalog# : 20298, Cas# :
2095719-92-7
)
ASTX029 is a highly potent and selective dual-mechanism ERK inhibitor. ASTX029 inhibi
AZD-4818
(Catalog# : 20297, Cas# :
1003566-93-5
)
AZD-4818 is a chemokine CCR1 antagonist that is used for the treatment of chronic obs
Adavivint
(Catalog# : 20289, Cas# :
1467093-03-3 (free base)
)
A2793
(Catalog# : 20286, Cas# :
88349-90-0
)
A2793 is an inhibitor of TRESK (IC50 value of 6.8 μM for mTRESK). A2793 inhibited TW
ABT-384
(Catalog# : 20281, Cas# :
868623-40-9
)
ABT-384 是 11β-羟基类固醇脱氢酶 1 (HSD-1) 的有效选择性抑制剂,该
AN 0128
(Catalog# : 20269, Cas# :
872044-70-7
)
AN 0128, also known as CRM-0005 and ONT-0001, is a tumour necrosis factor alpha (TNF-
Almonertinib
(Catalog# : 20267, Cas# :
1899921-05-1
)
Almonertinib is an orally available inhibitor of the epidermal growth factor receptor
ALC-0315
(Catalog# : 20264, Cas# :
2036272-55-4
)
ALC-0315 is a synthetic cationic lipid (or ionizable lipid). It is a colorless oily m
AP1189 acetate
(Catalog# : 2105071, Cas# :
959850-74-9
)
AP1189 is a melanocortin receptor agonist on MC1 and MC3 receptors.
AMG-221
(Catalog# : 21223, Cas# :
1095565-81-3
)
AMG-221, BVT-83370, is a potent and selective 11β-HSD1 inhibitor. AMG-221 decreased
ACT-389949 (ACT389949)
(Catalog# : 20211801, Cas# :
1258417-54-7
)
ACT-389949 is a potent and selective agonist of formyl peptide receptor type 2 (FPR2)
AT-56
(Catalog# : 20111201, Cas# :
162640-98-4
)
AT-56 is a selective, competitive, and highly bioavailable inhibitor of lipocalin-typ
ASN007
(Catalog# : 20103001, Cas# :
2055597-12-9
)
ASN007 , a novel oral ERK inhibitor , has shown anti-tumor activity in both solid tum
AB-680
(Catalog# : 2091501, Cas# :
2105904-82-1
)
AB-680一种是高效、可逆和选择性CD73抑制剂。AB-680是第一个临床使
Apilimod mesylate ( STA-5326 )
(Catalog# : 23948, Cas# :
870087-36-8
)
Apilimod, also known as STA-5326, is a potent IL-12/IL-23 inhibitor. Apilimod inhibit
AVN-101 HCl
(Catalog# : 2071801, Cas# :
1061354-48-0
)
AVN-101是一种非常有效的5-HT7受体拮抗剂(Ki = 153 pM),对5-HT6、5-H
APX-115 freebase
(Catalog# : 2071628, Cas# :
1270084-92-8
)
Apcin
(Catalog# : 2071626, Cas# :
300815-04-7
)
Apcin is an inhibitor of the anaphase-promoting complex/cyclosome (APC/C). It acts by
Astemizole
(Catalog# : 2071552, Cas# :
68844-77-9
)
Astemizole is a histamine H1-receptor antagonist. Astemizole competitively binds to h
ARV-771
(Catalog# : 2071539, Cas# :
1949837-12-0
)
ARV-771 is a small-molecule pan-BET degrader. ARV-771 demonstrates dramatically impro
AZD-7648
(Catalog# : 2071531, Cas# :
2230820-11-6
)
AZD-7648 is a potent and selective DNA-PK inhibitor.
AWZ1066S
(Catalog# : 2071530, Cas# :
239272-16-1
)
AWZ1066S is a highly specific anti-Wolbachia drug candidate for a short-course treatm
AER-271
(Catalog# : 2071523, Cas# :
634913-39-6
)
AER-271 is a potent aquaporin-4 (AQP4) inhibitor. AER-271 blocks acute cerebral edema
ABX-1431
(Catalog# : 2071517, Cas# :
1446817-84-0
)
ABX-1431 is a covalent, irreversible MGLL inhibitor. ABX-1431 is currently entering c
AZ31
(Catalog# : 2071508, Cas# :
2088113-98-6
)
AZ31 is a potent and highly selective ATM inhibitor.
AB-423
(Catalog# : 2071503, Cas# :
1572510-80-5
)
AB-423 is a novel inhibitor of hepatitis b virus pregenomic rna encapsidation
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
MGD-28
(Catalog# : 25073, Cas# :
2991818-13-2
)
MGD-28 is a potent molecular glue degrader that demonstrates significant in vitro eff
TG101209 analog 1
(Catalog# : 25072)
TG101209 analog 1 (Compound 8h) is an inhibitor of BUB1B with an IC50 of 10.36 μ M.
AT-007
(Catalog# : 25071, Cas# :
2170729-29-8
)
AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase in
TAK-653
(Catalog# : 25070, Cas# :
1358751-06-0
)
TAK-653 is a novel AMPA receptor potentiator, strictly potentiating a glutamate-induc
Emavusertib
(Catalog# : 25069, Cas# :
1801344-14-8
)
Emavusertib, also known as CA-4948 is a potent IRAK4/FLT3 inhibitor with anti-tumor a
Roginolisib
(Catalog# : 25068, Cas# :
1305267-37-1
)
Roginolisib, also known as MSC2360844 and IOA-244, is a potent, orally active and sel
NT219
(Catalog# : 25067, Cas# :
1198078-60-2
)
NT219 is a novel inhibitor of the insulin/igf signaling cascade (iis), mediating a lo
SPB linker
(Catalog# : 25066, Cas# :
858128-57-1
)
SPB is a agent-linker conjugate for ADC with potent anti-inflammatory activity by usi
JTE-151
(Catalog# : 20594, Cas# :
1404380-58-0
)
JTE-151 是一种 RORγ 抑制剂,可通过抑制与 Th17 细胞活化相关的 ROR
Ecopipam ( SCH 39166 )
(Catalog# : 25065, Cas# :
112108-01-7
)
Ecopipam (SCH 39166) 是一种有效的、选择性、具有口服活性的多巴胺