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others
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Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
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Thiazoles
Trifluoroborates
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
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Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
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产品名字索引 C
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产品名字索引 C
CNX-1351
(Catalog# : 185174, Cas# :
1276105-89-5
)
CNX-1351是PI3K的选择性共价抑制剂。
CGP60474
(Catalog# : 185171, Cas# :
164658-13-3
)
CGP60474是一种有效的双cdk1/cdk2抑制剂(IC50值分别为20和50 nM)。
COH29
(Catalog# : 184127, Cas# :
1190932-38-7
)
COH29是一种可口服的、芳香的取代噻唑和人核糖核苷酸还原酶(RNR)
CIL56
(Catalog# : 18491, Cas# :
300802-28-2
)
CIL56是一种YAP1抑制剂。它的作用是诱导非凋亡细胞死亡,触发细胞
Casopitant甲磺酸盐
(Catalog# : 18444, Cas# :
414910-30-8
)
Casopitant甲磺酸盐是一种中枢作用的神经激肽(NK1)受体拮抗剂,具有
COTI-2
(Catalog# : 184320, Cas# :
1039455-84-9
)
COTI-2是P53基因调制器和AKT2抑制剂。OTI-2在体外和体内都对多种人类
CBL0137
(Catalog# : 184319, Cas# :
314761-14-3
)
CBL0137激活p53并抑制NF-kB,它还能抑制组蛋白分子伴侣FACT,FACT促进染
CPI-444
(Catalog# : 18439, Cas# :
1202402-40-1
)
CPI-444,又名V81444,是一种腺苷A2A受体的口服拮抗剂。
CCG-203971
(Catalog# : 18437, Cas# :
1443437-74-8
)
CCG-203971是前列腺癌细胞系PC-3中SRE活化的抑制剂(IC50 = 6.4 μM),能够
CP-376395 free base
(Catalog# : 184213, Cas# :
175140-00-8
)
CP-376395 is a CRF1-selective antagonist. CRF1 receptor signaling regulates food and
Copanlisib HCl
(Catalog# : 18351, Cas# :
1402152-13-9
)
Copanlisib也称为BAY 80 - 6946,是一个强有力的磷酸肌醇3-激酶(PI3K)抑制
CB-03-01
(Catalog# : 1712153, Cas# :
19608-29-8
)
CB-03-01, also known as cortexolone 17alpha-propionate, is a topical and peripherally
Cenicriviroc ( TAK-652 )
(Catalog# : S510902, Cas# :
497223-25-3
)
Cenicriviroc(TAK-652, TBR-652) 是一种CCR2和CCR5受体抑制剂,临床上它被用
CHIR99021 HCl
(Catalog# : 179825, Cas# :
1797989-42-4
)
CHIR99021,又被称为 CT99021,是糖原合成酶激酶3β(GSK3β)抑制剂,
CDDO
(Catalog# : 92304, Cas# :
218600-44-3
)
CDDO是一种合成的齐墩果烷型三萜阻断诱导型一氧化氮合酶和诱导
CVT-10216
(Catalog# : 179818, Cas# :
1005334-57-5
)
CVT-10216是强有力的和有选择性的,乙醛脱氢酶2(ALDH2)的可逆性抑
卡米诺霉素盐酸盐
(Catalog# : 17914, Cas# :
52794-97-5
)
卡米诺霉素盐酸盐是一种蒽环类抗肿瘤抗生素类的洋红色马杜拉细
Cambinol
(Catalog# : 178313, Cas# :
14513-15-6
)
Cambinol是一种SIRT抑制剂。它能抑制促炎性细胞因子的表达,提高模
2-氯-4-(甲基氨基)-5-嘧啶甲醛
(Catalog# : 1781601, Cas# :
839708-50-8
)
2-氯-4-(甲基氨基)-5-嘧啶甲醛;2-chloro-4-(methylamino) pyrimidine-5-carbaldeh
2-吗啉-4-基-6-噻蒽-1-基吡喃-4-酮
(Catalog# : 1781504, Cas# :
119671-47-5
)
2-吗啉-4-基-6-噻蒽-1-基吡喃-4-酮;2-Chloro-6-morpholinopyran-4-one
CCT196969
(Catalog# : 178913, Cas# :
1163719-56-9
)
CCT196969,是一种pan-RAF / SFK抑制剂对治疗单纯的BRAF和NRAS突变型黑色
CCT365623
(Catalog# : 2017876)
CCT365623是一种赖氨酰化氧抑制剂。
CM-579
(Catalog# : 2017874, Cas# :
1846570-40-8
)
CM-579是一种生物活性化学药品 。
C188-9
(Catalog# : 2017873, Cas# :
432001-19-9
)
C188-9是一种生物活性化学品。
5-氯-2-氰基苯硼酸
(Catalog# : 20178120, Cas# :
1072946-52-1
)
5-氯-2-氰基苯硼酸
CY5.5-SE
(Catalog# : 20177314, Cas# :
442912-55-2
)
2-[5-[3-[6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-1,3-dihydro-1,1-dimethyl-6,8-d
头孢曲松钠
(Catalog# : 17032406, Cas# :
73384-59-5
)
头孢曲松是一种用于治疗多种细菌感染的抗生素。
头孢布烯
(Catalog# : 17032405, Cas# :
97519-39-6
)
头孢布烯(Sch39720)是第三代头孢菌素类抗生素。
头孢他啶
(Catalog# : 17032404, Cas# :
72558-82-8
)
头孢他啶(GR20263)是一种用于治疗多种细菌感染的抗生素。
头孢拉定
(Catalog# : 17032403, Cas# :
38821-53-3
)
头孢拉定是第一代头孢菌素类抗生素。
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag