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抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
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Angiogenesis
Apoptosis
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Cytoskeletal Signaling
Cell Cycle
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DNA Damage
Stem Cells & Wnt
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Neuronal Signaling
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Metabolism
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Proteases
Immunology & Inflammation
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others
PROTAC
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Anilines
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Deuterated
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Iodos
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
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定制合成
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订购信息
联系我们
公司简介
联系我们
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产品名字索引 C
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产品名字索引 C
Coelenterazine
(Catalog# : 6111016, Cas# :
55779-48-1
)
Coelenterazine
1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine
(Catalog# : 61110004, Cas# :
1228780-72-0
)
1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine
CC0651
(Catalog# : 611933, Cas# :
1319207-44-7
)
CC0651 is an allosteric inhibitor of the human cdc34 ubiquitin-conjugating enzyme tha
CDKI-73
(Catalog# : 611920, Cas# :
1421693-22-2
)
CDKI-73 is a potent CDK9 inhibitor with Ki of 4 nM; shows selective toxicity to CLL c
CDK9-IN-6
(Catalog# : 611919, Cas# :
1391855-95-0
)
CDK9-IN-6 is a CDK9 inhibitor, refers to Example 399 in WO 2012101062 A1
Ca2+ channel agonist 1
(Catalog# : 611918, Cas# :
1402821-24-2
)
Ca2+ channel agonist 1 is a N-type Ca2+ channel activity agonist, with EC50 of 14.23
CX-4945 sodium salt
(Catalog# : 611912, Cas# :
1309357-15-0
)
CX-4945 (Silmitasertib) sodium salt is a potent and selective ATP-competitive small m
CAL-130 Racemate
(Catalog# : 611824, Cas# :
474012-90-3
)
CAL-130 racemate is a novel phosphoinositide 3-kinase (PI3K) inhibitor. It is reporte
CAL-130 Hydrochloride
(Catalog# : 611823, Cas# :
1431697-78-7
)
CAL-130 Hcl is a novel phosphoinositide 3-kinase (PI3K) inhibitor. It is reported tha
CAL-130
(Catalog# : 611822, Cas# :
1431697-74-3
)
CAL-130 is a novel phosphoinositide 3-kinase (PI3K) inhibitor. It is reported that co
Compound 401
(Catalog# : 611816, Cas# :
168425-64-7
)
Compound 401 is a synthetic inhibitor of DNA-PK (IC50 = 0.28 M) that also targets mTO
CC-115 hydrochloride
(Catalog# : 611815, Cas# :
1300118-55-1
)
CC-115 hydrochloride is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM). CC-115 shows go
3 CAI
(Catalog# : 611801, Cas# :
28755-03-5
)
3CAI is a potent allosteric and specific AKT inhibitor, which exerts efficacy in vitr
Chrysophanic acid
(Catalog# : 161009017, Cas# :
481-74-3
)
Chrysophanic acid preferentially blocked proliferation in SNU-C5 cells but not in oth
CAY10505
(Catalog# : 160926016, Cas# :
1218777-13-9
)
CAY10505 is a phosphatidylinositol 3-kinase- inhibitor , was found to significantly i
CH5132799 (PA-799)
(Catalog# : 160926015, Cas# :
1007207-67-1
)
CH5132799, also known as PA-799, is a novel class I PI3K inhibitor, which exhibited a
CCT245737
(Catalog# : 16090101, Cas# :
1489389-18-5
)
CCT245737(CCT-245737, CAS 1489389-18-5) is the first orally active, clinical developm
CWHM-12
(Catalog# : 16071407, Cas# :
1564286-55-0
)
vitro ligand-binding assays, with somewhat less potency against v5 than against the o
CMK
(Catalog# : 16071401, Cas# :
821794-90-5
)
CMK
Copanlisib
(Catalog# : 16070917, Cas# :
1032568-63-0
)
Copanlisib, also known as BAY 80-6946, is a phosphoinositide 3-kinase (PI3K) inhibito
CCT244747
(Catalog# : 16070913, Cas# :
1404095-34-6
)
CCT244747 is a novel potent, highly selective, orally active ATP-competitive CHK1 inh
CP-673451
(Catalog# : 16070704, Cas# :
343787-29-1
)
CP-673451 is a selective inhibitor of PDGFR/ with IC50 of 10 nM/1 nM in cell-free ass
CHIR-99021
(Catalog# : 16062904, Cas# :
252917-06-9
)
CHIR-99021, also known as CT99021, is a glycogen synthase kinase 3 (GSK3) inhibitor t
CA-074
(Catalog# : 16062115, Cas# :
134448-10-5
)
CA-074
CF-102
(Catalog# : 16053104, Cas# :
163042-96-4
)
CF-102, also known as 2-Cl-IB-MECA, is an orally bioavailable, synthetic, highly sele
CHIR-090
(Catalog# : SSC65304, Cas# :
728865-23-4
)
CHIR-090 is a potent LpxC inhibitor, displays two-step time-dependent inhibition and
4-cyclopropylphenylacetic acid
(Catalog# : 032509, Cas# :
40641-90-5
)
Coming soon!
2-Chloro-3-fluoro-4-(trifluoromethyl)pyridine
(Catalog# : 032506, Cas# :
628692-22-8
)
Coming soon!
CEP-1347
(Catalog# : 032402, Cas# :
156177-65-0
)
Coming soon!
CPI-203
(Catalog# : 030201, Cas# :
1446144-04-2
)
CPI 203 is a novel potent, selective and cell permeable inhibitor of the bromodomain
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag