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Bromides
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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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others
PROTAC
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Amino Acids
Anilines
Boronic Acids
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Carboxes
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Deuterated
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公司简介
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产品名字索引 E
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产品名字索引 E
Enarodustat ( JTZ-951 )
(Catalog# : 2073104, Cas# :
1262132-81-9
)
Enarodustat ( JTZ-951 ) is an orally-active HIF-PH inhibitor with an EC50 of 0.22 Μm
Empesertib
(Catalog# : 2071554, Cas# :
1443763-60-7
)
Empesertib, also known as BAY1161909, is an orally bioavailable, selective inhibitor
EIDD-1931
(Catalog# : 2071537, Cas# :
3258-02-4
)
EIDD-1931 is a promising COVID-19 inhibitor. EIDD-1931 has broad spectrum antiviral a
ethyl 2-(2-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetate
(Catalog# : 2062030, Cas# :
2107880-93-1
)
Ethacrynic acid
(Catalog# : 2061703, Cas# :
58-54-8
)
Etharcrynic Acid is a compound that inhibits symport of sodium, potassium, and chlori
EB-3D
(Catalog# : 2061302, Cas# :
1839150-63-8(溴化物
)
EB-3D is a novel potent and selective choline kinase ChoKα inhibitor. EB-3D Induces
Elexacaftor
(Catalog# : 2052801, Cas# :
2216712-66-0
)
Elexacaftor, also known as VX-445 and WHO 11180, is a next-generation cystic fibrosis
EC-5026
(Catalog# : 2051508, Cas# :
1809885-32-2
)
EC5026, also known as BPN-19186, is a first-in-class, potent and orally active solubl
恩替替尼二盐酸盐
(Catalog# : 1843212, Cas# :
2137030-98-7
)
Ensartinib is an orally available small molecule inhibitor of the receptor tyrosine k
Evenamide HCl
(Catalog# : 112594, Cas# :
1092977-06-4
)
Evenamide HCl ( CAS 1092977-06-4) ,a sodium channel blocker, shows efficacy in a broa
Evenamide
(Catalog# : 112593, Cas# :
1092977-61-1
)
venamide is a sodium and/or calcium channel modulator. Evenamide may be potentia usef
2-乙酰基-4-溴苯甲酸乙酯
(Catalog# : 95071, Cas# :
182567-89-1
)
2-乙酰基-4-溴苯甲酸乙酯
Ertapenem
(Catalog# : 19318, Cas# :
153832-46-3
)
Ertapenem是一种肠外碳青霉烯类药物,对多种-内酰胺酶失活具有高
依普沙坦
(Catalog# : 192182, Cas# :
133040-01-4
)
依普沙坦是一种具有竞争性和可逆性的血管紧张素受体拮抗剂,用
EX-229游离酸
(Catalog# : 192153, Cas# :
1219739-36-2
)
EX-229,又称AMPK激活剂991,是一种新型的AMPK激活剂,能增加小鼠骨
依克立达盐酸盐
(Catalog# : 19121, Cas# :
143851-98-3
)
依克立达盐酸盐,又称GF120918A,是一种p -糖蛋白(P-gp)抑制剂,已作
E7820
(Catalog# : 1812293, Cas# :
289483-69-8
)
E7820是一种小分子芳香磺胺衍生物,具有潜在的抗血管生成和抗肿
EMD638683
(Catalog# : 1810253, Cas# :
1181770-72-8
)
EMD638683是一种有效的SGK1抑制剂, IC50值为3 μM。
E2012
(Catalog# : 1810231, Cas# :
870843-42-8
)
E2012是γ-secretase分泌酶调制器(GSM)。
EBI-2511
(Catalog# : 1810165, Cas# :
2098546-05-3
)
EBI-2511是非霍奇金淋巴瘤有效的口服活性EZH2抑制剂。
Entasobulin
(Catalog# : 186293, Cas# :
501921-61-5
)
Entasobulin是一种β-tubulin聚合抑制剂,具有潜在的抗癌活性。
环氧丙烷D
(Catalog# : 186292, Cas# :
189453-10-9
)
环氧丙烷D是从纤维素粘液杆菌中分离出来的一种天然聚酮化合物
EZM2302
(Catalog# : 186272, Cas# :
1628830-21-6
)
EZM2302是一种有效的,选择性的,可口服的精氨酸甲基转移酶CARM1抑
依沙替康甲磺酸盐
(Catalog# : 186271, Cas# :
169869-90-3
)
依沙替康也叫DX 8951,是一种半合成的水溶性喜树碱衍生物,具有
艾菲康唑
(Catalog# : 186213, Cas# :
164650-44-6
)
艾菲康唑是一种三唑类抗真菌药。它被批准用于加拿大和美国作为
Erteberel
(Catalog# : 186157, Cas# :
533884-09-2
)
Erteberel,也称为LY500307,选择性雌激素受体β受体激动剂(ERβ)是治疗良
Edonerpic maleate
(Catalog# : 18671, Cas# :
519187-97-4
)
Edonerpic,也被称为T-817,是一种神经保护剂。
内昔芬 E-异构体盐酸盐
(Catalog# : 184124, Cas# :
1197194-61-8
)
内昔芬 E-异构体是一种他莫昔芬的代谢物和有效的选择性雌激素反
Ensartinib ( X396 )
(Catalog# : 184321, Cas# :
1370651-20-9
)
Ensartinib is an orally available small molecule inhibitor of the receptor tyrosine k
eCF506 ( 别名:NXP 900 )
(Catalog# : 18382, Cas# :
1914078-41-3
)
eCF506靶向一种叫做Src酪氨酸激酶的分子,这是乳腺癌细胞生长和传
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag