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Metabolism
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others
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分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
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Thiazoles
Trifluoroborates
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联系我们
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 E
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产品名字索引 E
eCF506 ( 别名:NXP 900 )
(Catalog# : 18382, Cas# :
1914078-41-3
)
eCF506靶向一种叫做Src酪氨酸激酶的分子,这是乳腺癌细胞生长和传
Esaxerenone
(Catalog# : 1710121, Cas# :
1632006-28-0
)
Esaxerenone(cs-3150,xl-550)是一种非甾体类抗盐皮质激素Exelixis发现
EBE-A22
(Catalog# : 179831, Cas# :
229476-53-3
)
EBE-A22是PD 153035衍生物。EBE-A22,在EGF-R TK上无影响但保持高细胞毒
EPZ015666
(Catalog# : 011309, Cas# :
1616391-65-1
)
EPZ-015666 是一种强效、选择性的口服生物药,PRMT5抑制剂与Ki为5 nm
EED226
(Catalog# : 178311, Cas# :
2083627-02-3
)
EED226是一种强效、选择性抑制剂,口服生物EED抑制剂。在EZH2MUT临
厄达替尼(JNJ-42756493)
(Catalog# : 651701, Cas# :
1346242-81-6
)
Erdafitinib(JNJ-42756493) is a potent and selective panfibroblast growth factor recep
Ethyl 2-cyclohexyl-2-oxoacetate
(Catalog# : 178157, Cas# :
13275-31-5
)
Ethyl 2-cyclohexyl-2-oxoacetate
E7449
(Catalog# : 178903, Cas# :
1140964-99-3
)
E7449是一种可口服的小分子抑制剂,核酶聚(ADP-核糖)聚合酶(PARP)1和
Elenbecestat ( E2609 )
(Catalog# : 2017878, Cas# :
1388651-30-6
)
Elenbecestat是一种β-Site淀粉样前体蛋白裂解酶BACE)抑制剂,主要用
依托泊苷磷酸酯
(Catalog# : 20178213, Cas# :
117091-64-2
)
依托泊苷磷酸盐是一种半合成足叶草毒素的磷酸盐。
Elamipretide
(Catalog# : 20178210, Cas# :
736992-21-5
)
Elamipretide, 也称为MTP-131或D-Arg-Dmt-Lys-Phe-NH2,是一种心肌过氧化酶抑
[(1S)-2-(3,5-二氟苯基)-1-[(2S)-环氧乙烷基]乙基]氨基甲酸叔丁酯
(Catalog# : 20177314, Cas# :
388071-27-0
)
[(1S)-2-(3,5-二氟苯基)-1-[(2S)-环氧乙烷基]乙基]氨基甲酸叔丁酯
Etrasimod
(Catalog# : 17031018, Cas# :
1206123-37-6
)
Etrasimod,也被称为APD334,是一种多功能S1P1受体的功能拮抗剂,用
eFT-508
(Catalog# : 17031010, Cas# :
1849590-01-7
)
eFT-508 (eFT508)是一种有效且选择性的MNK1 / 2抑制剂,可能导致肿瘤细
盐酸Epetraborole
(Catalog# : 17022806, Cas# :
1234563-16-6
)
盐酸Epetraborole是一种新型的leucyl - trna合成酶(LeuRS)抑制剂。
依利格鲁司特
(Catalog# : 17022718, Cas# :
491833-29-5
)
依利格鲁司特, 也叫Genz-112638, 是一种有效的选择性的葡萄糖酰胺合
EX-527 S-enantiomer
(Catalog# : 17011802, Cas# :
848193-68-0
)
EX-527 S-enantiomer是一种有效的选择性SIRT1抑制剂,IC50为123 nM;没有对
EX-527 R-enantiomer
(Catalog# : 17011801, Cas# :
848193-69-1
)
EX-527 R-enantiomer是对活性形式EX-527 S-enantiomer(推测为参考)的负控制
4E1RCat
(Catalog# : 17011301, Cas# :
328998-25-0
)
4E1RCat是eIF4F翻译起始复合物的一种抑制剂,它阻止eIF4E:eIF4G和eIF4E
Etomoxir钠盐
(Catalog# : 17011103, Cas# :
828934-41-4
)
Etomoxir是一种在线粒体内膜的外表面的一种不可逆转的CPT-1抑制剂
Eganelisib ( IPI-549 )
(Catalog# : 711401, Cas# :
1693758-51-8
)
Eganelisib (IPI-549) 是一种首创、口服、高选择性 PI3Kγ 抑制剂,单独
Ezutromid
(Catalog# : 16122944, Cas# :
945531-77-1
)
Ezutromid, also known as BMN-195 and SMTC-1100, is a first orally bioavailable utroph
EXP-3174
(Catalog# : 16122943, Cas# :
124750-92-1
)
EXP-3174, also known as Losartan Carboxylic Acid, is a physiologically active metabol
Ertiprotafib
(Catalog# : 16122942, Cas# :
251303-04-5
)
Ertiprotafib, also known as PTP-112, is a Protein Tyrosine Phosphatase 1B Inhibitor (
Eptapirone
(Catalog# : 16122941, Cas# :
179756-85-5
)
Eptapirone, also known as F11440, is a potent, selective, high efficacy 5-HT1A recept
Eprodisate Sodium
(Catalog# : 16122940, Cas# :
36589-58-9
)
Eprodisate, also known as 3-PDS; NC-503; 3PDS, is an orally available disodium salt f
Emeramide ( BDTH2 )
(Catalog# : 16122939, Cas# :
351994-94-0
)
Emeramide, also known as BDTH2, is a mercury and heavy metal chelator. BDTH2 molecule
EMD534085
(Catalog# : 16122938, Cas# :
858668-07-2
)
EMD534085 is a kinesin inhibitor currently in clinical development.
Ellipticine
(Catalog# : 16122811, Cas# :
519-23-3
)
Ellipticine is a DNA intercalating agent and a DNA topoisomerase II inhibitor. Ellipt
Elacestrant dihydrochloride
(Catalog# : 16122810, Cas# :
1349723-93-8
)
Elacestrant dihydrochloride, also known as RAD1901, is an orally available, selective
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
TRPM4-IN-2
(Catalog# : 24147, Cas# :
667411-04-3
)
TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibi
Isolithocholic Acid
(Catalog# : 24146, Cas# :
1534-35-6
)
Isolithocholic acid is a bile acid that is formed via microbial metabolism of lithoch
H2-Gamendazole
(Catalog# : 24145, Cas# :
877768-84-8
)
H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycysti
CPI-455 HCl
(Catalog# : 24144, Cas# :
2095432-28-1
)
CPI-455 is a potent and selective inhibitor of KDM5 demethylases which reduces surviv
KH-3
(Catalog# : 24143, Cas# :
1215115-03-9
)
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC50 value
Stafib-2
(Catalog# : 24142, Cas# :
2097938-74-2
)
Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with
TCRS-417
(Catalog# : 24141, Cas# :
2032123-28-5
)
TCRS-417 (T417) is a small molecule compound capable of docking to the interface betw
PST3 1a
(Catalog# : 24140, Cas# :
1096144-06-7
)
PST3 1a is a Novel selective inhibitor of the N-acetylglucosamine glycosyltransferase
YTX-465
(Catalog# : 24139, Cas# :
2225824-53-1
)
YTX-465 is a SCD inhibitor. YTX-465 strongly reduced fatty desaturation in a concentr
CAY10566
(Catalog# : 10403, Cas# :
944808-88-2
)
Coming soon!