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抑制剂/受体激动剂
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Cytoskeletal Signaling
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Metabolism
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分子砌块
Aldehydes
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Anilines
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Bromides
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Deuterated
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
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订购信息
联系我们
公司简介
联系我们
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产品名字索引 I
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产品名字索引 I
IDH889
(Catalog# : 19319, Cas# :
1429179-07-6
)
IDH889是一种有效的选择性IDH1抑制剂。IDH899为IDH (R132H) IC50 = 20 nM;细
INCB3284甲磺酸盐
(Catalog# : 191143, Cas# :
887401-93-6
)
INCB3284是一种有效的、选择性的、可口服的hCCR2拮抗剂。
Indeglitazar
(Catalog# : 1812131, Cas# :
835619-41-5
)
Indeglitazar,也称为PPM-204和PLX-204,是一个可口服的过氧化物酶体增
IU1-47
(Catalog# : 181025, Cas# :
670270-31-2
)
IU1-47是一种有效且具有选择性的USP14抑制剂。
Inarigivir soproxil
(Catalog# : 186277, Cas# :
942123-43-5
)
Inarigivir soproxil,也被称为SB 9200,是一种抗病毒药物。
IT-901
(Catalog# : 186276, Cas# :
1584121-99-2
)
IT-901是一个血液恶性肿瘤抑制剂,通过阻断NF-κB-Controlled氧化应激反
INX 08189
(Catalog# : 186253, Cas# :
1234490-83-5
)
INX 08189 是一种RNA引导的RNA聚合酶(NS5B)抑制剂,可用于丙型肝炎病
IWP-O1
(Catalog# : 186222, Cas# :
2074607-48-8
)
IWP-O1是一种高效的Porcn抑制剂,对Wnt蛋白的分泌至关重要,它有助
INCB057643
(Catalog# : 185232, Cas# :
1820889-23-3
)
INCB057643是一种BET抑制剂。在卵巢癌中,INCB054329降低了同源重组效
Iberdomide
(Catalog# : 185216, Cas# :
1323403-33-3
)
Iberdomide,也称为CC-220,可用于治疗系统性红斑狼疮。
INCB3344
(Catalog# : 185215, Cas# :
1262238-11-8
)
INCB3344是CCR2受体的一种有效的选择性拮抗剂,它在结合拮抗的IC(5
iCRT3
(Catalog# : 18492, Cas# :
901751-47-1
)
iCRT3是Wnt/β-catenin信号的拮抗剂,在Wnt responsive STF16-luc reporter assay
IDO-IN-2
(Catalog# : 184317, Cas# :
1668565-74-9
)
IDO抑制剂1是IDO的有效抑制剂(吲哚胺-(2,3)-二氧合酶),IC50为3nm。
IPI-3063
(Catalog# : 18433, Cas# :
1425043-73-7
)
IPI-3063是一种选择性的Phosphoinoside-3-激酶p110δ 抑制剂。IPI-3063能有
5-碘-1-甲基咪唑
(Catalog# : 1712292, Cas# :
71759-88-1
)
5-碘-1-甲基咪唑是一种分子砌块。
6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-amine
(Catalog# : 1710123, Cas# :
1448427-99-3
)
6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-amine
IDRA-21
(Catalog# : 179134, Cas# :
22503-72-6
)
IDRA-21是一种阳性的AMPA受体调节剂。IDRA-21抑制突触和突触外NMDA受
ISCK03
(Catalog# : 1791118, Cas# :
945526-43-2
)
ISCK03是一种有效的c-kit抑制剂。ISCK03抑制在501mel人黑素瘤细胞的SC
IACS-9571
(Catalog# : 1783019, Cas# :
1800477-30-8
)
IACS-9571是一种有效的选择性TRIM24和BRPF1抑制剂。布罗莫结构域包括
Importazole
(Catalog# : 17031013, Cas# :
662163-81-7
)
Importazole是一种运输受体importin-β的小分子抑制剂,专门阻止import
IDE1
(Catalog# : 17030309, Cas# :
1160927-48-9
)
IDE1是一种高效的细胞渗透性明确内胚层形成诱导剂(EC50 = 125 nM,ESC
ISX-9
(Catalog# : 17022713, Cas# :
832115-62-5
)
ISX-9 is a neurogenic agent. Isx-9 promotes neurogenesis in vivo, enhancing the proli
Ixazomib (MLN-2238)
(Catalog# : 16123024, Cas# :
1072833-77-2
)
Ixazomib, also known as MLN-2238, is a potent proteasome inhibitor (PI) with potentia
Isovaleramide
(Catalog# : 16123023, Cas# :
541-46-8
)
Isovaleramide, also known as NPS-1776, is a drug potentially for the treatment of mig
Isosorbide Mononitrate
(Catalog# : 16123022, Cas# :
16051-77-7
)
Isosorbide Mononitrate is a drug used principally in the treatment of angina pectoris
IQ-1S
(Catalog# : 16123021, Cas# :
23146-22-7
)
IQ-1S is a potent and selective c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits mur
Ingenol Mebutate
(Catalog# : 16123020, Cas# :
75567-37-2
)
Ingenol mebutate, also known as ingenol-3-angelate, is a substance found in the sap o
Imperatorin
(Catalog# : 16123019, Cas# :
482-44-0
)
Imperatorin, aslo known as Pentosalen, Marmelosin, is a furocoumarin and a phytochemi
Iloprost
(Catalog# : 16123018, Cas# :
78919-13-8
)
Iloprost is a drug used to treat pulmonary arterial hypertension (PAH), scleroderma,
IKK-16
(Catalog# : 16123017, Cas# :
873225-46-8
)
IKK-16 is a potent and slective inhibitor of IB kinase (IKK) (IC50 values are 40, 70
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
TRPM4-IN-2
(Catalog# : 24147, Cas# :
667411-04-3
)
TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibi
Isolithocholic Acid
(Catalog# : 24146, Cas# :
1534-35-6
)
Isolithocholic acid is a bile acid that is formed via microbial metabolism of lithoch
H2-Gamendazole
(Catalog# : 24145, Cas# :
877768-84-8
)
H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycysti
CPI-455 HCl
(Catalog# : 24144, Cas# :
2095432-28-1
)
CPI-455 is a potent and selective inhibitor of KDM5 demethylases which reduces surviv
KH-3
(Catalog# : 24143, Cas# :
1215115-03-9
)
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC50 value
Stafib-2
(Catalog# : 24142, Cas# :
2097938-74-2
)
Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with
TCRS-417
(Catalog# : 24141, Cas# :
2032123-28-5
)
TCRS-417 (T417) is a small molecule compound capable of docking to the interface betw
PST3 1a
(Catalog# : 24140, Cas# :
1096144-06-7
)
PST3 1a is a Novel selective inhibitor of the N-acetylglucosamine glycosyltransferase
YTX-465
(Catalog# : 24139, Cas# :
2225824-53-1
)
YTX-465 is a SCD inhibitor. YTX-465 strongly reduced fatty desaturation in a concentr
CAY10566
(Catalog# : 10403, Cas# :
944808-88-2
)
Coming soon!