武汉永璨生物科技有限公司
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抑制剂/受体激动剂
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Indoles and Oxindoles
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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On Sale
中间体
技术服务
定制合成
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订购信息
联系我们
公司简介
联系我们
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产品名字索引 N
N-(2-methylbenzyl)-4,5-dihydro-1H-imidazol-2-amine
(Catalog# : 2062031, Cas# :
38941-29-6
)
5-(N-PHTHALIMIDO)-2-PENTANONE
(Catalog# : 2062010, Cas# :
3197-25-9
)
N-Fmoc-O-[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-α-D-galactopyranosyl]-L-serine
(Catalog# : 2061601, Cas# :
120173-57-1
)
NTP42
(Catalog# : 2051509, Cas# :
2055599-51-2
)
NTP42 is a novel antagonist of the thromboxane prostanoid receptor (TP), currently in
N-Boc-吡咯
(Catalog# : S-204153, Cas# :
5176-27-2
)
N-(4-戊炔基)酞酰亚胺
(Catalog# : S-204150, Cas# :
6097-07-0
)
N-benzyl-2,4-dichloropyrimidine-5-carboxamide
(Catalog# : 197101, Cas# :
1019115-13-9
)
NVS-ZP7-4
(Catalog# : 204506, Cas# :
2349367-89-9 (free base)
)
NVS-ZP7-4 is a potent ZIP7 Inhibitor, which inhibits Notch signaling with IC50 of 0.1
NVP-2
(Catalog# : 193205, Cas# :
1263373-43-8
)
NVP-2是细胞周期蛋白依赖性激酶CDK9的抑制剂。
NS-1652
(Catalog# : 19361, Cas# :
1566-81-0
)
NS-1652是一种阴离子电导抑制剂。
NCT-506
(Catalog# : 19354, Cas# :
2231098-99-8
)
NCT-506是一种口服生物可利用醛脱氢酶1A1 (ALDH1A1)抑制剂,IC50为7nm。
Nelotanserin
(Catalog# : 191121, Cas# :
839713-36-9
)
Nelotanserin( APD125) is a potent and selective human 5-hydroxytryptamine2A inverse a
ND-646
(Catalog# : 191102, Cas# :
1434639-57-2
)
ND-646是ACC酶ACC1和ACC2的变构抑制剂,可阻止ACC亚基二聚化,在体内
ND-630
(Catalog# : 19133, Cas# :
1434635-54-7
)
ND-630,也称为GS-0976, NDI-010976和firsocostat, 是一种有效的ACC抑制剂。
Naquotinib游离
(Catalog# : 1812297, Cas# :
1448232-80-1
)
Naquotinib,又称ASP8273,是一种口服、不可逆、第三代、突变选择、
N6022
(Catalog# : 1811304, Cas# :
1208315-24-5
)
N6022是一种有效、选择性、可逆性和有效性的s -亚硝基谷胱甘肽还
Nexinhib20
(Catalog# : 1811152, Cas# :
331949-35-0
)
Nexinhib20是一种Rab27抑制剂,可以抑制中性粒细胞的胞外活动,在体
NGI-1
(Catalog# : 181171, Cas# :
790702-57-7
)
NGI-1,又称ML414,是低聚糖转移酶(OST)的一种细胞渗透性抑制剂。
NMS-E973
(Catalog# : 1810293, Cas# :
1253584-84-7
)
NMS-E973是一种新型、选择性和强效的热休克蛋白90 (Hsp90)抑制剂。
NCT-505
(Catalog# : 1810261, Cas# :
2231079-74-4
)
NCT-505是一种口服生物有效醛脱氢酶1A1 (ALDH1A1)抑制剂,具有较强的
NVP-BGG463
(Catalog# : 1810233, Cas# :
890129-26-7
)
NVP-BGG463是一种新型的II型激酶抑制剂,靶向CDK2。
NS1619
(Catalog# : 1810227, Cas# :
153587-01-0
)
NS1619是一种Bkca开启工具或大电导Ca2+活化钾(Bkca, KCa1.1)通道激活器
Nacubactam
(Catalog# : 185169, Cas# :
1452458-86-4
)
Nacubactam, 也称为RG-6080, FPI-1459, 和OP-0595, 是一种β-内酰胺酶抑制剂
Navarixin
(Catalog# : 185168, Cas# :
473727-83-2
)
Navarixin, 也称为SCH527123, PS291822和MK-7123, 是一种有效的CXCR2拮抗剂。
Nemorubicin
(Catalog# : 185167, Cas# :
108852-90-0
)
Nemorubicin,又名PNU152243A,是一种不同于其母体药物的doxorubicin衍生
Nolatrexed盐酸盐
(Catalog# : 185166, Cas# :
152946-68-4
)
Nolatrexed,也叫AG337,是一种具有潜在抗癌活性的胸腺嘧啶合成酶抑
Nucleozin
(Catalog# : 185164, Cas# :
341001-38-5
)
Nucleozin是一种杀毒剂。它的目标是一种核蛋白(NP),这是一种病毒
Nidufexor
(Catalog# : 184288, Cas# :
1773489-72-7
)
Nidufexor是一个法呢醇X受体(FXR)激动剂。
1NM-PP1
(Catalog# : 184174, Cas# :
221244-14-0
)
1NM-PP1 是一种有效的突变激酶抑制剂。
Netarsudil(Mesylate)
(Catalog# : 712181, Cas# :
1422144-42-0
)
Netarsudil( AR-11324) is a Rho-associated protein kinase inhibitor. Netarsudil is pot
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag