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Aldehydes
Amines
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Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
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Quinolines
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Thiazoles
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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On Sale
中间体
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订购信息
联系我们
公司简介
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产品名字索引 N
nor-NOHA醋酸盐
(Catalog# : 1710169, Cas# :
1140844-63-8
)
nor-NOHA是一种强效、选择性、竞争性、以及精氨酸酶的高亲和力抑
NMS-P118
(Catalog# : 17101311, Cas# :
1262417-51-5
)
NMS-P118是一种有效的、可口服、高选择性PARP-1抑制剂具有优良的AD
盐酸萘替芬
(Catalog# : 1791514, Cas# :
65473-14-5
)
萘替芬是一种丙烯胺抗真菌药物的局部治疗足癣、股癣、体癣(真
Neflamapimod
(Catalog# : 1791317, Cas# :
209410-46-8
)
Neflamapimod,也称为VX-745,VRT-031745和VD-31745,是高度有效的和选择性
盐酸纳洛酮
(Catalog# : 178305, Cas# :
357-08-4
)
纳洛酮是一种μ-opioid受体(MOR)逆受体激动剂。纳洛酮针对在中枢神
3-Nitrosalicylic Acid Methyl Ester
(Catalog# : 178224, Cas# :
22621-41-6
)
3-Nitrosalicylic Acid Methyl Ester
N-甲氧基-N-甲基乙酰胺
(Catalog# : 178223, Cas# :
78191-00-1
)
N-Methoxy-N-methylacetamide
N-(4-(benzyloxy)-3-methoxybenzyl)-5-phenyl-N-(2-(pyridin-2-yl)ethyl)pentanamide
(Catalog# : 1781506, Cas# :
521310-51-0
)
N-(4-(Benzyloxy)-3-methoxybenzyl)-5-phenyl-N-(2-(pyridin-2-yl)ethyl)pentanamide
NIH-12848
(Catalog# : 1781103, Cas# :
959551-10-1
)
NIH-12848是一种普遍认为的磷脂酰肌醇5 -磷酸四激酶(PI5P4K)抑制剂。
Nazartinib (EGF816)
(Catalog# : 1781004, Cas# :
1508250-71-2
)
Nazartinib,也被称为EGF816,是一种口服可用,不可逆转的、第三代、
Netarsudil
(Catalog# : 1781001, Cas# :
1254032-66-0
)
<span style="color:#34495E;font-family:" font-size:14px;background-color
NSC781406
(Catalog# : 20178810, Cas# :
1676893-24-5
)
NSC781406是一种高效针对PI3K的IC50为2 nM的PI3K和mTOR抑制剂。
NCT-503
(Catalog# : 2017888, Cas# :
1916571-90-8
)
NCT-503是一种3 -磷酸甘油酸脱氢酶(PHGDH)抑制剂,抑制丝氨酸合成3 -磷
NGP-555
(Catalog# : 2017875, Cas# :
1304630-27-0
)
NGP 555正在被作为一种预防疾病老年痴呆症的治疗。
N-反式-阿魏酰酪胺
(Catalog# : 201708019, Cas# :
66648-43-9
)
N-反式-阿魏酰酪胺|N-Trans-Feruloyltyramine|(E)-3-(4-hydroxy-3-Methoxy-phenyl)-
NDGA
(Catalog# : 17030909, Cas# :
500-38-9
)
去甲二氢愈创木酸(NDGA),也被称为masoprocol,是一种天然抗氧化剂dica
诺拉曲特
(Catalog# : 17030908, Cas# :
147149-76-6
)
诺拉曲特,也叫AG337,是一种具有潜在抗癌活性的百里香酶抑制剂
NPS-1034
(Catalog# : 17030907, Cas# :
1221713-92-3
)
NPS-1034是一种新型的MET抑制剂,它能抑制活化的MET受体及其具有结
NVP-BEP800
(Catalog# : 17030906, Cas# :
847559-80-2
)
NVP-BEP800, 也称为BEP-800,是一种新型的、完全合成的口服生物可用抑
制霉菌素
(Catalog# : 17030905, Cas# :
1400-61-9
)
制霉菌素是一种多烯抗真菌药物,含有三种生物活性成分的抗生素
NCH-51
(Catalog# : 17030716, Cas# :
848354-66-5
)
NCH-51, 也叫PTACH,是一种组蛋白去乙酰化酶(HDAC)抑制剂。NCH-51抑制
NS-1643
(Catalog# : 17030715, Cas# :
448895-37-2
)
NS-1643是一种人类ether-a-go-go相关基因(hERG)KV11.1通道激活剂(EC50 = 10.
Nifenalol HCl
(Catalog# : 17030705, Cas# :
5704-60-9
)
Nifenalol,也叫INPEA,是一种新型的β-肾上腺素受体拮抗剂。
聚乙二醇纳诺醇
(Catalog# : 17030202, Cas# :
1354744-91-4
)
Naloxegol,也称为NKTR-118和AZ-13337019,是一种选择性的阿片拮抗剂,用于
尼拉帕尼盐酸盐
(Catalog# : 17030114, Cas# :
1038915-64-8
)
尼拉帕尼, 也称为MK-4827, 是一种具有潜在抗肿瘤活性的聚(ADP-核糖
那可汀盐酸盐
(Catalog# : 17022711, Cas# :
912-60-7
)
那可汀, 也被称为麻醉药物,阿片烷,是一种来自罂粟科植物的be
Nampt-IN-1
(Catalog# : 17022705, Cas# :
1698878-14-6
)
Nampt-IN-1是NAMPT的一种新型抑制剂,IC50分别为18 nM(NCI- H1155细胞),4
NSC12
(Catalog# : 17021317, Cas# :
102586-30-1
)
NSC12是一种可用于抑制FGF2 / FGFR相互作用并具有良好的抗肿瘤活性
NS-398 (NS398)
(Catalog# : 17011106, Cas# :
123653-11-2
)
NS-398是一种cyclooxygenase-2 (COX-2)的选择性抑制剂。
Netarsudil (AR-13324) 2HCl
(Catalog# : 1710901, Cas# :
1253952-02-1
)
Netarsudil (a.k.a. AR-13324)是一种ROCK抑制剂,Ki值为 0.2-10.3 nM。它目前
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag