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Cytoskeletal Signaling
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Cas Index 1
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Cas Index 1
141286-78-4 | 2,6-DIFLUORO-4-[2-(PHENYLSULFONYLAMINO)E
(Catalog# : G20379)
1215012-74-0 | DDD100097
(Catalog# : 20307)
DDD100097 is an inhibitor of Trypanosoma brucei N-myristoyltransferase (TbNMT) with m
1263774-59-9 | Delgocitinib(JTE-052)
(Catalog# : 20273)
Delgocitinib, also known as LEO-124249 and JTE052, is a potent and selective JAK inhi
1269726-67-1 | Dapaconazole
(Catalog# : 20272)
Dapaconazole is an antifungal drug candidate. Phase II trials showed that Dapaconazol
1505484-82-1 | Daridorexant ( ACT541468 )
(Catalog# : 20265)
Daridorexant is a dual orexin receptor antagonist (DORA) designed and developed for t
1024828-77-0 | Difelikefalin
(Catalog# : 21257)
Difelikefalin HCl is in stock.Difelikefalin, also known CR-845; MR-13A-9; MR-13A9, is
1450662-05-1 | 2,4-dimethoxy-6-methylnicotinonitrile
(Catalog# : 21255)
2,4-dimethoxy-6-methylnicotinonitrile, is a key intermediate ofLirametostat ( CPI-120
1505515-69-4 | DS-6051B adipate
(Catalog# : 211153)
DS-6051B is an orally available inhibitor of the receptor tyrosine kinases C-ros onco
15893-52-4 | 2,4-Dihydroxy-7-methoxy-2H,1,4-benzoxazin-3(4H)one
(Catalog# : 2071630)
1903768-17-1 | Danicopan
(Catalog# : 2071535)
Danicopan, aslo known as ACH-4471 and ACH-0144471, is a highly potent, orally active
1233231-30-5 | DSP-2230
(Catalog# : 2071525)
DSP-2230 is a selective Nav1.7/Nav1.8 blocker.
1547757-91-4 | 1,4-diazaspiro[5.5]undecan-3-one
(Catalog# : 2071601)
1174321-06-2 | 5-(difluoromethyl)pyrazine-2-carboxylic acid
(Catalog# : 202326)
169194-80-3 | 1-(1,1-dimethyl-prop-2-ynyl)-4-methyl-piperazine
(Catalog# : 2062314)
106635-87-4 | 2-(4-((2,6-dimethoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)quinolin-8-yl)amino)pentyl)isoindoline-1,3-dione
(Catalog# : 2062309)
1922200-81-4 | 4-(3-(4-(4,5-dihydro-1H-imidazol-2-yl)-2-methoxy-3-nitrophenoxy)propyl)morpholine
(Catalog# : 2062021)
106635-86-3 | 2,6-DIMETHOXY-4-METHYL-5-[3-(TRIFLUOROMETHYL)PHENOXY]QUINOLIN-8-AMINE
(Catalog# : 2062013)
1174047-06-3 | 2,3-Dichloro-4-hydroxypyridine
(Catalog# : 2062012)
1442472-39-0 | DCC-2618 ( Ripretinib )
(Catalog# : 1811121)
Ripretinib, also known as DCC-2618, is a potent, orally active and selective KIT/PDGF
1234356-69-4 | Derazantinib
(Catalog# : 189273)
Derazantinib, also known as ARQ-087, is an orally bioavailable inhibitor of the fibro
1224606-06-7 | D-Lin-MC3-DMA
(Catalog# : 18942)
D-Lin-MC3-DMA is the most potent cationic lipid that has been synthesized for Lipid n
1799711-21-9 | dBET1
(Catalog# : 186261)
dBET1 is a competitive antagonist of BET bromodomains to hijack the Cereblon E3 ubiqu
144707-18-6 | 2-D08
(Catalog# : 186231)
2-D08 is a synthetic flavone that inhibits sumoylation. 2-D08 showed anti-aggregatory
181223-80-3 | DEL-22379
(Catalog# : 186155)
DEL-22379 is a potent and selective ERK Dimerization inhibitor.
189279-58-1 | Delafloxacin
(Catalog# : 18612)
Delafloxacin, also known as ABT-492, RX-3341 and WQ-3034, is a non-zwitterionic fluor
1219707-39-7 | Delpazolid
(Catalog# : 18611)
Delpazolid, also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone.
1616690-16-4 | Desidustat
(Catalog# : 185231)
Desidustat is an antianaemic drug candidate.
1104874-94-3 | Defensamide
(Catalog# : 184212)
Defensamide,也被称为MHP和甲基己酰酪氨酸,是鞘氨醇激酶(SPHK1)的激
1032571-01-9 | 6-(4,5-dihydro-1H-imidazol-2-yl)-2-methoxy-3-[3-(morpholin-4-yl)propoxy]aniline
(Catalog# : 2017080116)
6-(4,5-dihydro-1H-imidazol-2-yl)-2-methoxy-3-(3-morpholin-4-ylpropoxy)aniline
1073154-85-4 | Defactinib
(Catalog# : 120111)
Defactinib is a potent FAK phosphorylation inhibitor; overcomes YB-1Cmediated paclita
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2991818-13-2 | MGD-28
(Catalog# : 25073)
MGD-28 is a potent molecular glue degrader that demonstrates significant in vitro eff
| TG101209 analog 1
(Catalog# : 25072)
TG101209 analog 1 (Compound 8h) is an inhibitor of BUB1B with an IC50 of 10.36 μ M.
2170729-29-8 | AT-007
(Catalog# : 25071)
AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase in
1358751-06-0 | TAK-653
(Catalog# : 25070)
TAK-653 is a novel AMPA receptor potentiator, strictly potentiating a glutamate-induc
1801344-14-8 | Emavusertib
(Catalog# : 25069)
Emavusertib, also known as CA-4948 is a potent IRAK4/FLT3 inhibitor with anti-tumor a
1305267-37-1 | Roginolisib
(Catalog# : 25068)
Roginolisib, also known as MSC2360844 and IOA-244, is a potent, orally active and sel
1198078-60-2 | NT219
(Catalog# : 25067)
NT219 is a novel inhibitor of the insulin/igf signaling cascade (iis), mediating a lo
858128-57-1 | SPB linker
(Catalog# : 25066)
SPB is a agent-linker conjugate for ADC with potent anti-inflammatory activity by usi
1404380-58-0 | JTE-151
(Catalog# : 20594)
JTE-151 is a novel RORγ inverse agonist.
112108-01-7 | Ecopipam ( SCH 39166 )
(Catalog# : 25065)
Ecopipam ( SCH 39166 ) is a Selective Dopamine Receptor D1/D5 Antagonist used in the