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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
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Cas Index 1
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Cas Index 1
112275-50-0 | 1-Boc-hexahydro-1,4-diazepine
(Catalog# : 81024)
Coming soon!
13343-63-0 | Benzyl-2-acetamido-4,6-O-benzylidene-2-deoxy-α-D-glucopyranoside
(Catalog# : 80301)
Coming Soon
1009817-63-3 | b-AP15
(Catalog# : 73106)
b-AP15 is a specific inhibitor of the deubiquitinating enzymes Uch37 and Usp14 of the
188011-69-0 | Bikinin
(Catalog# : 61002)
Bikinin(Abrasin) is a potent inhibitor of plant GSK-3/Shaggy-like kinase; activates B
1538604-68-0 | BLU9931
(Catalog# : 60303)
BLU9931 is a potent and irreversible small-molecule inhibitor of FGFR4, as a targeted
1092443-52-1 | BS-181
(Catalog# : 52755)
BS-181 is a highly selective CDK7 inhibitor with IC50 of 21 nM. ; >40-fold selecti
19542-67-7 | BAY 11-7082
(Catalog# : 52713)
BAY 11-7082 is aNF-Binhibitor, inhibits TNF-inducedIBphosphorylation withIC50of 10 M
196309-76-9 | Bay 11-7085
(Catalog# : 52712)
BAY 11-7085 is an irreversible inhibitor of TNF-inducedIBphosphorylation withIC50of 1
153559-49-0 | Bexarotene
(Catalog# : 52601)
Bexarotene (Targretin) is a selective RXR agonist approved for the treatment of CTCL.
1397219-81-6 | BS-181 HCl
(Catalog# : 52578)
BS-181 HCl is a highly selectiveCDK7inhibitor withIC50of 21 nM. It is more than 40-fo
1174046-72-0 | BMS-794833
(Catalog# : 52205)
BMS-794833 is a potent ATP competitive inhibitor of Met/VEGFR2 with IC50 of 1.7/15 nM
1187594-09-7 | Baricitinib
(Catalog# : 51908)
Baricitinib (also known as LY3009104 or INCB028050) is a novel and potent small molec
1403859-14-2 | CC90001 free base
(Catalog# : 24095)
CC-90001 is a potent and selective JNK inhibitor, which is 12.9-fold more potent for
1261451-92-6 | 5-chloro-2-methoxypyridine-3-sulfonyl chloride
(Catalog# : 24022)
5-chloro-2-methoxypyridine-3-sulfonyl chloride, CAS 1261451-92-6.
1370032-20-4 | CUR5g
(Catalog# : 20678)
CUR5g is a potent autophagy inhibitor.
1112968-42-9 | Contezolid free base
(Catalog# : 20653)
Contezolid (Youxitai ®), an orally administered oxazolidinone antibacterial agent, i
1610759-22-2 | CFI-402257 free base
(Catalog# : 20626)
CFI-402257 was discontinued for commercial reason.
1345858-76-5 | CYM-50308
(Catalog# : 20488)
CYM 50308 is a novel agonist of SIP4 (EC50 = 56 nM) that displays 37-fold selectivity
1623747-97-6 | CRANAD-28
(Catalog# : 20478)
CRANAD-28 is a blood brain barrier (BBB) penetrable two-photon imaging probe. It acts
1621164-74-6 | Camlipixant ( BLU-5937 )
(Catalog# : 20455)
Camlipixant is an investigational, twice-daily oral P2X3 receptor antagonist for the
127094-58-0 | 6-Chloro-4-hydroxy-[1,5]naphthyridine-3-carboxylic acid ethyl ester
(Catalog# : 20423)
1446321-95-4 | 3-(chloromethyl)-2-(1-isopropyl-1H-pyrazol-5-yl)pyridine hydrochloride
(Catalog# : 20408)
1786438-30-9 | CR8 hydrochloride
(Catalog# : L20350)
CR8 is a potent and selective inhibitor of CDK. CR8 is a more potent pyridyl analogue
1618658-88-0 | CC-671
(Catalog# : L20343)
CC-671 is a potent and selective dual inhibitor of TTK (Mps1) and CLK2.
1258296-60-4 | CS-2667
(Catalog# : L20340)
RO495 (CS-2667) is a potent inhibitor of Non-receptor tyrosine-protein kinase 2 (TYK2
1038984-34-7 | 3-cyclopropyl-7-methyl-6-nitro-2H-benzo[e][1,3]oxazin-4(3H)-one
(Catalog# : 20328)
1262414-04-9 | Cenerimod ( ACT-334441 )
(Catalog# : 20313)
Cenerimod is a potent and orally active immunomodulator, exhibited EC50 value of 2.7
16499-64-2 | 4-chloro-6-(trifluoromethyl)quinazoline
(Catalog# : 20310)
1979939-16-6 | CRT0273750
(Catalog# : 20258)
CRT0273750 modulates LPA levels in plasma and is suitable for in vivo studies.
1628265-17-7 | 2-chloro-4-(4-fluorophenyl)thiazole-5-carbonitrile
(Catalog# : 2091202)
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag