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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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PROTAC
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Cas Index 1
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Cas Index 1
1256580-46-7 | Alectinib(CH5424802)
(Catalog# : 51907)
Alectinibis a second-generation, orally active, potent and highly selective inhibitor
1173900-33-8 | AZD6482
(Catalog# : 51603)
AZD6482 is aPI3Kinhibitor withIC50of 10 nM, 8-, 87- and 109-fold more selective to PI
1204144-28-4 | AZD1208
(Catalog# : 51702)
AZD1208 is a potent, highly selective, and orally available Pim kinase inhibitor that
1124329-14-1 | AZ3146
(Catalog# : 51903)
AZ3146 is a selectiveMps1inhibitor withIC50of ~35 nM, contributes to recruitment of C
1056901-62-2 | AT13148
(Catalog# : 51902)
AT13148, a first-in-class multi-AGC kinase inhibitor, against gastric cancer cells. A
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
1809010-52-3 | Berotralstat HCl
(Catalog# : 20619)
Berotralstat HCl is a novel selective inhibitor of plasma kallikrein, blocking the en
1672668-24-4 | Belzutifan
(Catalog# : 20606)
Belzutifan, also known as PT2977 and MK-6482, is HIF-2alpha inhibitor. PT2977 binds t
1478364-68-9 | BI-1467335 HCl
(Catalog# : 20601)
BI-1467335, also known as PXS-4728A, is a SSAO/VAP inhibitor potentially for the trea
1440964-89-5 | Bozitinib
(Catalog# : 20599)
Bozitinib is a highly selective c-MET kinase inhibitor with blood-brain barrier perme
1815613-42-3 | BMS-986176
(Catalog# : 20597)
BMS-986176, also known as LX9211, is a highly selective, CNS penetrant, potent AAK1 i
120533-76-8 | BML-278
(Catalog# : 20554)
BML-278 is an activator of sirtuin 1 (SIRT1) that has an EC150 value (effective conce
1478712-37-6 | BMS-986120
(Catalog# : 20519)
BMS-986120 is a potent and selective oral antagonist of protease-activated receptor-4
1478711-48-6 | BMS-986141
(Catalog# : 20518)
BMS-986141 is an Orally-Active Small-Molecule Antagonist of the Platelet Protease-Act
1423719-30-5 | BI 1015550 ( Nerandomilast )
(Catalog# : 230402)
BI 1015550 ( Nerandomilast )is an oral, preferential inhibitor of phosphodiesterase 4
1883299-62-4 | Brepocitinib ( PF-06700841 )
(Catalog# : 232251)
Brepocitinib is a potential first-in-class dual, selective inhibitor of TYK2 and JAK1
1798787-27-5 | BIIB068
(Catalog# : 20453)
1428652-17-8 | Baxdrostat
(Catalog# : 20451)
Baxdrostat is an aldosterone synthase inhibitor.
1912445 -55-6 | BMS-986195
(Catalog# : 20444)
1912445-55-6 | Branebrutinib
(Catalog# : 20428)
Branebrutinib, also known as BMS-986195, is a potent, covalent, irreversible inhibito
1060810-24-3 | 1-(4-Bromo-6- methylpyridin-2- yl)ethan-1-one
(Catalog# : 171454)
1-(4-Bromo-6- methylpyridin-2- yl)ethan-1-one, CAS 1060810-24-3.
195615-84-0 | Blarcamesine HCl
(Catalog# : 6111905)
Anavex2-73 is a muscarinic/σ1 ligand. ANAVEX2-73 (0.01-3.0 mg/kg i.p.) alleviated th
1055-55-6 | Bunamidine hydrochloride
(Catalog# : 20271)
Bunamidine is a anti-parasitic drug, which was approved by FDA for the treatment of t
1303515-32-3 | BI-187004
(Catalog# : 21224)
BI-187004, also known as VTP-34072, is an 11β-hydroxysteroid dehydrogenase 1 inhibit
1207853-23-3 | Benzyl(2S,5R)-5-amino-2-methylpiperidine-1-carboxylatehydrochloride
(Catalog# : 20103006)
1333714-43-4 | Benpyrine racemate
(Catalog# : 2091907)
(Rac)-Benpyrine is a racemate of Benpyrine. (Rac)-Benpyrine is a potent and orally ac
1660117-38-3 | BI-894999
(Catalog# : 2091902)
BI-894999 is a potent and selective BET inhibitor potentially useful for the Treatmen
1628264-07-2 | 6-bromo-2-ethyl-N,8-dimethylimidazo[1,2-a]pyridin-3-amine
(Catalog# : 2091201)
1818314-88-3 | BMS-1166
(Catalog# : 2073102)
BMS-1166is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM, antagoni
1891087-61-8 | BAY-1816032
(Catalog# : 2071615)
BAY-1816032 is a potent and oral available BUB1 (budding uninhibited by benzimidazole
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag