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PI3K/Akt/mTOR
Epigenetics
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Angiogenesis
Apoptosis
Autophagy
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MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Anilines
Boronic Acids
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Cas Index 1
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Cas Index 1
1258296-60-4 | CS-2667
(Catalog# : L20340)
RO495 (CS-2667) is a potent inhibitor of Non-receptor tyrosine-protein kinase 2 (TYK2
1038984-34-7 | 3-cyclopropyl-7-methyl-6-nitro-2H-benzo[e][1,3]oxazin-4(3H)-one
(Catalog# : 20328)
1262414-04-9 | Cenerimod ( ACT-334441 )
(Catalog# : 20313)
Cenerimod is a potent and orally active immunomodulator, exhibited EC50 value of 2.7
16499-64-2 | 4-chloro-6-(trifluoromethyl)quinazoline
(Catalog# : 20310)
1979939-16-6 | CRT0273750
(Catalog# : 20258)
CRT0273750 modulates LPA levels in plasma and is suitable for in vivo studies.
1628265-17-7 | 2-chloro-4-(4-fluorophenyl)thiazole-5-carbonitrile
(Catalog# : 2091202)
1279680-68-0 | CL2A-SN38 DCA
(Catalog# : 2071556)
CL2A-SN38 is a SN38 derivative with a peptide-linker which can easily react with anti
1846570-31-7 | CM-272
(Catalog# : 2071538)
CM-272 is a first-in-class reversible dual small molecule inhibitor against G9a and D
189746-21-2 | 5-chloro-2,6-dimethoxy-4-methyl-8-nitroquinoline
(Catalog# : 2062026)
1246964-32-8 | CLEFMA
(Catalog# : 615201)
CLEFMA has anti-proliferative activity in H441 cells. CLEFMA may induce autophagic ce
145915-58-8 | CGP52411
(Catalog# : 2061306)
CGP52411, also known as DAPH, is a selective inhibitor of the epidermal growth factor
199735-88-1 | CADD522
(Catalog# : 2051505)
CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA bind
1010100-07-8 | CC-885
(Catalog# : 2041501)
CC-885 is a potent Cereblon Modulator with potent antitumor activity mediated through
1860875-51-9 | CC-90009
(Catalog# : 203071)
CC-90009 is a modulator of cereblon (CRBN), which is part of the cullin 4-RING E3 ubi
189746-19-8 | 5-Chloro-2,6-Dimethoxy-4-Methylquinoline
(Catalog# : 4281903)
5-Chloro-2,6-Dimethoxy-4-Methylquinoline, CAS 189746-19-8, is a key drug intermediate
1181083-81-7 | CLP-290
(Catalog# : 193286)
CLP-290 is a novel KCC2 modulator and prodrug of CLP-257, highly selective for KCC2 o
1802632-22-9 | CT-1812
(Catalog# : 193283)
CT-1812 is a first-in-class, orally available sigma-2/PGRMC1 antagonist (alpha beta o
1384860-29-0 | Conteltinib
(Catalog# : 19342)
Conteltinib is a tyrosine kinase inhibitor and an antineoplastic.
1358099-18-9 | C25-140
(Catalog# : 192274)
C25-140 is the first in class protein-protein interaction inhibitor of a RING-E3 liga
1095382-05-0 | CCT-137690
(Catalog# : 192192)
CCT137690, an aurora kinase inhibitor CCT137690, is a highly selective, orally bioava
1418274-28-8 | Cilofexor ( GS-9674 )
(Catalog# : 19132)
Cilofexor (also known as GS-9674) is a nonsteroidal farnesoid X receptor (FXR) agonis
1402709-93-6 | CCT241736
(Catalog# : 1812283)
CCT241736 is a potent and orally active and dual FLT3-Aurora inhibitor.
1801343-74-7 | CA-4948
(Catalog# : 1811292)
CA-4948 is a bioactive chemical.
192322-50-2 | CGP-71683A HCl
(Catalog# : 18792)
CGP 71683A is a potent and highly selective non-peptide antagonist of the NPY Y(5) re
1437321-24-8 | CEP-40783
(Catalog# : 186281)
CEP-40783, also known as RXDX-106, is a potent, selective and orally available inhibi
125316-60-1 | CD437
(Catalog# : 185316)
CD437 is a synthetic retinoid that is an RARγ-selective agonist.
1345810-21-0 | CB-1158
(Catalog# : 185315)
CB-1158, also known as INCB01158, is a potent arginase inhibitor.
153259-65-5 | Cilomilast
(Catalog# : 185291)
Cilomilast (Ariflo, SB-207,499) is a drug which was developed for the treatment of re
1276105-89-5 | CNX-1351
(Catalog# : 185174)
CNX-1351 is a selective covalent Inhibitor of PI3Kα.
164658-13-3 | CGP60474
(Catalog# : 185171)
CGP60474 is a potent dual cdk1/cdk2 inhibitor (IC50 values are 20 and 50 nM, respecti
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2991818-13-2 | MGD-28
(Catalog# : 25073)
MGD-28 is a potent molecular glue degrader that demonstrates significant in vitro eff
| TG101209 analog 1
(Catalog# : 25072)
TG101209 analog 1 (Compound 8h) is an inhibitor of BUB1B with an IC50 of 10.36 μ M.
2170729-29-8 | AT-007
(Catalog# : 25071)
AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase in
1358751-06-0 | TAK-653
(Catalog# : 25070)
TAK-653 is a novel AMPA receptor potentiator, strictly potentiating a glutamate-induc
1801344-14-8 | Emavusertib
(Catalog# : 25069)
Emavusertib, also known as CA-4948 is a potent IRAK4/FLT3 inhibitor with anti-tumor a
1305267-37-1 | Roginolisib
(Catalog# : 25068)
Roginolisib, also known as MSC2360844 and IOA-244, is a potent, orally active and sel
1198078-60-2 | NT219
(Catalog# : 25067)
NT219 is a novel inhibitor of the insulin/igf signaling cascade (iis), mediating a lo
858128-57-1 | SPB linker
(Catalog# : 25066)
SPB is a agent-linker conjugate for ADC with potent anti-inflammatory activity by usi
1404380-58-0 | JTE-151
(Catalog# : 20594)
JTE-151 is a novel RORγ inverse agonist.
112108-01-7 | Ecopipam ( SCH 39166 )
(Catalog# : 25065)
Ecopipam ( SCH 39166 ) is a Selective Dopamine Receptor D1/D5 Antagonist used in the