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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
Intermediates
Services
Custom Synthesis
Process Development
Ordering
Contact Us
About Us
Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
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Services
Custom Synthesis
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Name Index I
IC87201
(Catalog# : 16122820, Cas# :
866927-10-8
)
IC87201 is a nNOS-PDZ/PSD-95-PDZ inhibitor. IC87201 showed great promise in cellular
ITSA-1 (ITSA1)
(Catalog# : 16122741, Cas# :
200626-61-5
)
ITSA-1 (ITSA1) is an HDAC activator via TSA suppression, but shows no activity toward
5-Iodotubercidin
(Catalog# : 16122729, Cas# :
24386-93-4
)
5-Iodotubercidin is a potent adenosine kinase inhibitor with IC50 of 26 nM. It inhibi
IMR-1A
(Catalog# : 6111507, Cas# :
331862-41-0
)
IMR-1A is the metabolite of IMR-1. IMR-1 is a novel class of Notch inhibitors targeti
Itacitinib
(Catalog# : 6111505, Cas# :
1334298-90-6
)
Itacitinib (INCB039110) is an oral selective JAK1 inhibitor. Itacitinib is an inh
IC261
(Catalog# : 611914, Cas# :
186611-52-9
)
IC261 is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50
Imeglimin
(Catalog# : 611811, Cas# :
775351-65-0
)
Imeglimin(EMD-387008) is the first in a new tetrahydrotriazine-containing class of or
IC-87114
(Catalog# : 160926004, Cas# :
371242-69-2
)
It Inhibits p110, p110 and p110 only at much higher concentrations. It does not inhib
Iniparib
(Catalog# : 16071103, Cas# :
160003-66-7
)
Iniparib, also known as BSI-201, is a small-molecule prodrug inhibitor of the nuclear
Idasanutlin (RG7388)
(Catalog# : 16070812, Cas# :
1229705-06-9
)
Idasanutlin; also known as RG7388 and RO5503781, is a highly potent and selective MDM
Istradefylline
(Catalog# : 16070809, Cas# :
155270-99-8
)
Istradefylline (KW-6002) is a selective antagonist at the A2A receptor. It has been f
Ilomastat
(Catalog# : 16070104, Cas# :
142880-36-2
)
Ilomastat, also known as GM6001 and galardin, is a broad-spectrum matrix metalloprote
IRAK-1-4 Inhibitor I
(Catalog# : 16062116, Cas# :
448906-42-1
)
IRAK-1-4 Inhibitor I
Ivosidenib
(Catalog# : 16053001, Cas# :
1448347-49-6
)
Ivosidenib is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1)
INCB 024360
(Catalog# : 032405, Cas# :
1204669-58-8
)
INCB 024360 is a potent and novel indoleamine-2,3 dioxygenase (IDO)inhibitor with an
5-Iodo-2-isopropyl-1-methyl-1H-imidazole
(Catalog# : 021701, Cas# :
851870-28-5
)
Coming soon!
Irbinitinib
(Catalog# : 011310, Cas# :
937263-43-9
)
Irbinitinib is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent ag
INK-128
(Catalog# : 011121, Cas# :
1224844-38-5
)
INK 128 is a potent and selective mTOR inhibitor with IC50 of 1 nM; >200-fold less
IWP L6
(Catalog# : 011109, Cas# :
1427782-89-5
)
IWP L6 is a Porcn inhibitor with EC50 of 0.5 nM.
Icotinib
(Catalog# : 011101, Cas# :
610798-31-7
)
Icotinib is an orally available quinazoline-based inhibitor of epidermal growth facto
IWP-3
(Catalog# : 010801, Cas# :
687561-60-0
)
IWP-3 is an inhibitor of Wnt production.
Isoquinolin-7-ylboronic acid
(Catalog# : 010612, Cas# :
1092790-21-0
)
This product is for custom synthesis.
IKK 16
(Catalog# : 010419, Cas# :
1186195-62-9
)
Coming soon!
IDO-IN-2
(Catalog# : 123002, Cas# :
914471-09-3
)
IDO-IN-2 is a potent IDO1 inhibitor(IC50=10 nM) with desirable pharmaceutical propert
INT-747
(Catalog# : 122905, Cas# :
459789-99-2
)
INT-747 is a potent and selective FXR agonist(EC50=99 nM) endowed with anticholestati
ICG-001
(Catalog# : 122801, Cas# :
780757-88-2
)
ICG-001 is a potent, specific inhibitor of the canonical Wnt signaling pathway in can
Ixabepilone
(Catalog# : 122307, Cas# :
219989-84-1
)
Ixabepilone is an epothilone B analog and nontaxane microtubule-stabilizing compound
Isavuconazole
(Catalog# : 120801, Cas# :
241479-67-4
)
Coming soon!
IRAK-1-4 Inhibitor I
(Catalog# : 110907, Cas# :
509093-47-4
)
IRAK-1-4 Inhibitor I is a IRAK-4 Inhibitor with IC50 of 200 nM, and is an anti-inflam
IWP-2
(Catalog# : 110602, Cas# :
686770-61-6
)
IWP-2 is an inhibitor of Wnt secretion and processing. It blocks Wnt-dependent signal
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
HC-5404
(Catalog# : 24112, Cas# :
3034479-99-4
)
HC-5404 is a novel, highly selective and potent PERK inhibitor.
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno