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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
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Bromides
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Chiral Compounds
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Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
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Phenols
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Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
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Name Index R
(R) QuinoxP(R)
(Catalog# : 16062107, Cas# :
866081-62-1
)
(R) QuinoxP(R)
Ro41-1049(HCl)
(Catalog# : 166154, Cas# :
127500-84-9
)
Ro 41-1049 is an inhibitor of the enzyme monoamine oxidase type A(MAO-A).
RS-1
(Catalog# : 16061501, Cas# :
312756-74-4
)
4-BroMo-N-(4-broMophenyl)-3-[[(phenylMethyl)aMino]sulfonyl]benzaMide;RAD51-stimulator
Relugolix
(Catalog# : 16060701, Cas# :
737789-87-6
)
Relugolix, also known as TAK-385, is a luteinizing hormone-releasing hormone (LH-RH)
RO31-8220 mesylate
(Catalog# : 16060303, Cas# :
138489-18-6
)
Ro 31-8220 is a PKC-inhibitor, which inhibits stimulated fluid pinocytosis of human P
R112
(Catalog# : 031003, Cas# :
575474-82-7
)
R112 is an ATP-competitive inhibitor of Syk kinase with a Ki of 96 nM. R112 inhibits
Ro 46-2005
(Catalog# : 031001, Cas# :
150725-87-4
)
Ro 46-2005 is a novel synthetic non-peptide endothelin receptor antagonist, inhibits
RAD140
(Catalog# : 030909, Cas# :
1182367-47-0
)
Coming soon!
Robalzotan tartrate hydrate
(Catalog# : 011907, Cas# :
169758-66-1
)
Coming soon!
Radotinib
(Catalog# : 011307, Cas# :
926037-48-1
)
Radotinib is an orally available, a second-generation tyrosine kinase inhibitor of Bc
Ruxolitinib
(Catalog# : 01118, Cas# :
941678-49-5
)
Ruxolitinib is the first potent, selective, JAK1/2 inhibitor to enter the clinic with
Ro 5126766
(Catalog# : 010812, Cas# :
946128-88-7
)
Ro 5126766 is a potent and selective dual RAF/MEK inhibitor. For SK-MEL-28, SK-MEL-2,
Refametinib
(Catalog# : 010810, Cas# :
923032-37-5
)
Refametinib is an orally bioavailable selective MEK inhibitor with potential antineop
Raltegravir
(Catalog# : 010412, Cas# :
518048-05-0
)
Raltegravir is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in
Ridaforolimus
(Catalog# : 123018, Cas# :
572924-54-0
)
Ridaforolimus is a selective mTOR inhibitor with IC50 of 0.2 nM; while not classified
R428
(Catalog# : 123010, Cas# :
1037624-75-1
)
R428 is a potent and selective small-molecule inhibitor(IC50=14 nM), blocks the activ
Rucaparib
(Catalog# : 123005, Cas# :
283173-50-2
)
Rucaparib is an inhibitor of PARP with Ki of 1.4 nM for PARP1, also showing binding a
RO4929097
(Catalog# : 123001, Cas# :
847925-91-1
)
RO4929097 is a secretase inhibitor with IC50 of 4 nM, inhibiting cellular processing
R788
(Catalog# : 122928, Cas# :
901119-35-5
)
Fostamatinib is a small molecule Syk kinase inhibitor with potential anti-inflammator
R406 free base
(Catalog# : 122927, Cas# :
841290-80-0
)
R406 is a potent inhibitor of immunoglobulin E (IgE)- and IgG-mediated activation of
RGB-286638 free base
(Catalog# : 122917, Cas# :
784210-88-4
)
RGB-286638 is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/5 nM for cyclin
Ravidasvir hydrochloride
(Catalog# : 122904, Cas# :
1303533-81-4
)
Ravidasvir is a second-generation, orally active, potent and selective HCV NS5A prote
Rofecoxib
(Catalog# : 122837, Cas# :
162011-90-7
)
Rofecoxib is a synthetic, nonsteroidal derivative of phenyl-furanone with antiinflamm
Remodelin hydrobromide
(Catalog# : 122823, Cas# :
1622921-15-6
)
Remodelin HBr salt is a novel potent and selective inhibitor of the acetyl-transferas
RTA-408
(Catalog# : 122808, Cas# :
1474034-05-3
)
RTA-408 is a synthetic triterpenoid that potently activates the antioxidative transcr
Rolapitant
(Catalog# : 122804, Cas# :
552292-08-7
)
Rolapitant is a potent, highly selective, long-acting Neurokinin-1 (NK-1) receptor an
RQ 00203078
(Catalog# : 122521, Cas# :
1254205-52-1
)
RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist (IC50
RI-1
(Catalog# : 122404, Cas# :
415713-60-9
)
RI-1 is a RAD51 inhibitor with IC50 ranging from 5 to 30 M.
Rabeprazole sodium
(Catalog# : 122403, Cas# :
117976-90-6
)
Rabeprazole sodium is an antiulcer drug in the class of proton pump inhibitors.
RAF265
(Catalog# : 122202, Cas# :
927880-90-8
)
RAF265 is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 n
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
MGD-28
(Catalog# : 25073, Cas# :
2991818-13-2
)
MGD-28 is a potent molecular glue degrader that demonstrates significant in vitro eff
TG101209 analog 1
(Catalog# : 25072)
TG101209 analog 1 (Compound 8h) is an inhibitor of BUB1B with an IC50 of 10.36 μ M.
AT-007
(Catalog# : 25071, Cas# :
2170729-29-8
)
AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase in
TAK-653
(Catalog# : 25070, Cas# :
1358751-06-0
)
TAK-653 is a novel AMPA receptor potentiator, strictly potentiating a glutamate-induc
Emavusertib
(Catalog# : 25069, Cas# :
1801344-14-8
)
Emavusertib, also known as CA-4948 is a potent IRAK4/FLT3 inhibitor with anti-tumor a
Roginolisib
(Catalog# : 25068, Cas# :
1305267-37-1
)
Roginolisib, also known as MSC2360844 and IOA-244, is a potent, orally active and sel
NT219
(Catalog# : 25067, Cas# :
1198078-60-2
)
NT219 is a novel inhibitor of the insulin/igf signaling cascade (iis), mediating a lo
SPB linker
(Catalog# : 25066, Cas# :
858128-57-1
)
SPB is a agent-linker conjugate for ADC with potent anti-inflammatory activity by usi
JTE-151
(Catalog# : 20594, Cas# :
1404380-58-0
)
JTE-151 is a novel RORγ inverse agonist.
Ecopipam ( SCH 39166 )
(Catalog# : 25065, Cas# :
112108-01-7
)
Ecopipam ( SCH 39166 ) is a Selective Dopamine Receptor D1/D5 Antagonist used in the