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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
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Indoles and Oxindoles
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
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Name Index R
((1R,2S)-2-(3-fluorophenyl)-2-(hydroxymethyl)cyclopropyl)methyl acetate
(Catalog# : 2062004, Cas# :
1369768-29-5
)
Rigosertib
(Catalog# : 690120, Cas# :
592542-59-1
)
Rigosertib(ON-01910) is a multi-kinase inhibitor and a selective anti-cancer agent, w
Resatorvid
(Catalog# : 206102, Cas# :
243984-11-4
)
Resatorvid, also known as TAK-242, is a cell-permeable inhibitor of TLR4 signaling, b
RU320521
(Catalog# : 204503, Cas# :
2262452-06-0
)
RU320521, also known as RU521; RU.521 is a potent and selective inhibitor of cGAS, in
(R)-tert-butyl 2-(2-ethynyl-2-methylpyrrolidin-1-yl)acetate
(Catalog# : 580586, Cas# :
2086689-88-3
)
(R)-tert-butyl 2-(2-ethynyl-2-methylpyrrolidin-1-yl)acetate, CAS 2086689-88-3, is a v
Remetinostat
(Catalog# : 193111, Cas# :
946150-57-8
)
Remetinostat, also known as SHP-141, is a topical formulation containing the histone
RG7834
(Catalog# : 19355, Cas# :
2072057-17-9
)
RG7834,also known as RO7020322, is a novel oral HBV viral gene expression inhibitor
RWJ-56110
(Catalog# : 19353, Cas# :
252889-88-6
)
RWJ-56110 is a selective protease-activated receptor-1 (PAR1) antagonist. It blocks t
RBC8
(Catalog# : 19313, Cas# :
361185-42-4
)
RBC8 is a RalA and RalB GTPase inhibitor (EC50 ~3.5 μM). RBC8 suppresses growth of x
Rogaratinib
(Catalog# : 192277, Cas# :
1443530-05-9
)
Rogaratinib, also known as BAY-1163877, is an aberrant fibroblast growth factor recep
Rebimastat
(Catalog# : 192254, Cas# :
259188-38-0
)
Rebimastat, also known as BMS275291, is a sulfhydryl-based second-generation matrix m
Retosiban
(Catalog# : 192193, Cas# :
820957-38-8
)
Retosiban, also known as GSK-221149-A; is an oral active, potent and selective, sub-n
RKI-1313
(Catalog# : 19183, Cas# :
1342276-76-9
)
RKI-1313 Negative control for RKI-1447 (GLXC-05200) which is a potent inhibitor of th
RGX-104 free form
(Catalog# : 19181, Cas# :
610318-54-2
)
RGX-104, also known as SB 742881, is a liver X receptor beta agonist with potential i
R547
(Catalog# : 1811151, Cas# :
741713-40-6
)
R547 is orally bioavailable diaminopyrimidine cyclin-dependent kinase inhibitor (CDKI
Regadenoson
(Catalog# : 1810224, Cas# :
313348-27-5
)
Regadenoson is an A2A adenosine receptor agonist that is a coronary vasodilator that
RMC-4550
(Catalog# : 186251, Cas# :
2172651-73-7
)
RMC-4550 is a potent and selective SHP2 inhibitor.
RGX-104 HCl
(Catalog# : 186234, Cas# :
610318-03-1
)
RGX-104 is a liver X receptor beta agonist with potential immunomodulating and antine
Resminostat HCl
(Catalog# : 185317, Cas# :
1187075-34-8
)
Resminostat HCl is a potent inhibitor of HDAC1/3/6.
Rovazolac
(Catalog# : 185234, Cas# :
1454288-88-0
)
Rovazolac is an anti-inflammatory drug candidate.
Rolapitant free base
(Catalog# : 185152, Cas# :
5552292-08-7
)
Rolapitant, also known as SCH-619734, is an orally bioavailable, centrally-acting, se
RO10-5824
(Catalog# : 185141, Cas# :
189744-46-5
)
RO10-5824 is a D4-selective partial agonist. RO10-5824 is a potent candidate for the
Ricasetron
(Catalog# : 184281, Cas# :
117086-68-7
)
Ricasetron, also known as Brl 46470, is antiemetic and axiolytic.
R-IMPP
(Catalog# : 18413, Cas# :
2133832-83-2
)
R-IMPP is an inhibitor of PCSK9 translation.
Rimegepant
(Catalog# : 18441, Cas# :
1289023-67-1
)
Rimegepant, aslo known as BMS-927711, is a potent, selective, competitive and orally
Ritlecitinib ( PF-06651600 )
(Catalog# : 18435, Cas# :
1792180-81-4
)
Ritlecitinib ( PF-06651600 ) is a potent and selective JAK3 inhibitor. PF-06651600, a
R-GNE-140
(Catalog# : 18432, Cas# :
2003234-63-5
)
R-GNE-140 a novel potent lactate dehydrogenase (LDHA) inhibitor with IC50 3nM for LDH
(2R,14R)-4-((R)-1-((R)-4-benzyl-2-oxooxazolidin-3-yl)-3-(tert-butoxycarbonyl)-1-oxopropan-2-yl)benzyl 2,4-dimethylbenzoate
(Catalog# : 183217, Cas# :
2097334-19-3
)
(2R,14R)-4-((R)-1-((R)-4-benzyl-2-oxooxazolidin-3-yl)-3-(tert-butoxycarbonyl)-1-oxopr
(R)-4-(2-(4-benzyl-2-oxooxazolidin-3-yl)-2-oxoethyl)benzyl 2,4-dimethylbenzoate
(Catalog# : 183216, Cas# :
2097334-18-2
)
(R)-4-(2-(4-benzyl-2-oxooxazolidin-3-yl)-2-oxoethyl)benzyl 2,4-dimethylbenzoate is a
Relebactam
(Catalog# : 1712156, Cas# :
1174018-99-5
)
Relebactam,也称为MK- 7655,一个强有力的、具有选择性的β-lactamase抑制
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
INDEX NAME NOT YET ASSIGNED
(Catalog# : 25002, Cas# :
2891709-58-1
)
HC-5404
(Catalog# : 25001, Cas# :
2247396-91-2
)
HC-5404 is a novel, highly selective and potent PERK inhibitor.
HC-5404-FU
(Catalog# : 24112, Cas# :
3034479-99-4
)
HC-5404-FU is a novel, highly selective and potent PERK inhibitor.
CMP-5 2HCl
(Catalog# : 24161, Cas# :
2309409-79-6
)
CMP-5 is a potent, specific, and selective PRMT5 inhibitor, while displays no activit
Wu-5
(Catalog# : 24160, Cas# :
2630378-05-9
)
Wu-5 is a USP10 inhibitor that can inhibit FLT3 and AMPK pathways, induce FLT3-ITD de
VU-29
(Catalog# : 24159, Cas# :
890764-36-0
)
VU 29 is a potent allosteric potentiator at the rat mGlu5 receptor (EC50 = 9 nM); bin
ML-202
(Catalog# : 24158, Cas# :
1221186-52-2
)
ML-202 is an activator of pyruvate kinase M2 (PKM2).
BTA-EG4 hydrate
(Catalog# : 24157, Cas# :
921193-28-4
)
BTA-EG4 is a catalase-amyloid interaction inhibitor, which can significantly enhance
CYD19
(Catalog# : 24156, Cas# :
2415281-52-4
)
CYD19 is a potent Snail/HDAC dual target inhibitor.
Phylloflavan
(Catalog# : 24155, Cas# :
98570-83-3
)
Phylloflavan is an antileishmanial agent with an intracellular EC50 of 3.2 nM in RAW