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Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
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Nitro Compounds
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联系我们
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
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Other Azoles
Other Heterocycles
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Cas号索引 1
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Cas号索引 1
158899-10-6 | TLN-232
(Catalog# : 18594)
TLN-232, 也称为CAP-232,是一种具有潜在抗肿瘤活性的合成环七肽。
140194-24-7 | 醋酸曲普瑞林
(Catalog# : 18592)
醋酸曲普瑞林是一种促性腺激素释放激素激动剂(GnRH激动剂),用作
1383816-29-2 | Tropifexor
(Catalog# : 18591)
Tropifexor, 也称为LJN452, 是一种用于治疗胆静性肝病和非酒精性脂肪
1702809-17-3 | THZ531
(Catalog# : 184172)
THZ531是一种共价CDK12和CDK13共价抑制剂。环素依赖性激酶12和13 (CDK
1802220-02-5 | TPX-0005
(Catalog# : 18423)
TPX-0005是一种Src/FAK/Janus激酶2 (JAK2)抑制剂。TPX-0005 + EGFR TKI抑制RTKs
1402601-82-4 | TUG-770
(Catalog# : 1791519)
TUG-770是高度有效的游离脂肪酸受体1(FFA1/GPR40)治疗2型糖尿病的激动
1429749-41-6 | Thiomyristoyl
(Catalog# : 1791113)
Thiomyristoyl是一种强效和特异性的IC50为28nM的SIRT2抑制剂。IC50与目标
1029877-94-8 | 琥珀酸曲格列汀
(Catalog# : 179811)
曲格列汀,也称为SYR472,是一种武田制药正在开发的治疗2型糖尿
1374516-07-0 | TUG-891
(Catalog# : 1783014)
TUG-891是一种有效且选择性的游离脂肪酸受体4(FFA4 / GPR120),它既显
1361951-15-6 | TP-3654
(Catalog# : 178303)
TP-3654是一种Pim-1和Pim-3激酶抑制剂,可用于治疗前列腺癌、急性髓
1326712-16-6 | TAK1抑制剂
(Catalog# : 1791412)
TAK1 inhibitor isis discontinued.TAK1抑制剂是一种有效的、相对选择性的
1351636-18-4 | Tirabrutinib游离 ( ONO-4059 )
(Catalog# : 17031303)
Tirabrutinib,也被称为ONO- 4059,是在抑制剂中,一种强大的、具有口
1610882-30-8 | TCS-OX2-29盐酸盐
(Catalog# : 17031302)
TCS-OX2- 29或TCS OX2 29,也被称为TCSOX229和TCS - OX229,是一种选择性的
1603845-32-4 | TX1-85-1
(Catalog# : 17030713)
TX1-85-1是一种ErbB3抑制剂. TX2-121-1可能通过异位机制发挥Her3依赖性
183204-72-0 | Tipiracil HCl
(Catalog# : 17030710)
Tipiralacil,又称TPI,是胸腺嘧啶磷酸化酶抑制剂(TPI)。Tipiracil是TAS
1234365-97-9 | Tenapanor HCl
(Catalog# : 17030113)
Tenapanor, 也称为AZD-1722和RDX 5791, 是钠-质子(Na(+)/ H(+))交换器NHE3的抑
150915-40-5 | 盐酸替罗非班
(Catalog# : 17030103)
替罗非班是一种抗血小板药物。它属于一种名为糖蛋白IIb / IIIa抑
135598-68-4 | TAS-109
(Catalog# : 17022810)
TAS-109, 也称为DFP-10917和CNDAC,是一种具有潜在抗肿瘤活性的核苷酸脱
1256037-58-7 | TRX818
(Catalog# : 17022401)
TRX-818是一种可口服的生物制剂,具有潜在的抗肿瘤活性和抗血管
15421-84-8 | 乐可安
(Catalog# : 17021310)
乐可安是一种PDGF拮抗剂,可抑制PDGF生成胶质瘤细胞的增殖。
1439901-97-9 | ONO-4059盐酸盐
(Catalog# : 17012103)
ONO-4059是BTK的选择性和新型抑制剂,IC50为2.2 nm,ONO-4059与B细胞内的
113942-30-6 | 替莫唑胺酸
(Catalog# : 17011905)
替莫唑胺酸, 也称为TMZA, 是一种具有明显抗癌活性的替奥米特(TMZ)
1609960-31-7 | TH588
(Catalog# : 17011728)
TH588是NUDT1的一种有效抑制剂,其IC50值为5nm,具有良好的代谢稳定
1415716-58-3 | TG6-10-1
(Catalog# : 17011727)
TG6-10-1是前列腺素E2受体亚型EP2的有效和选择性拮抗剂。
1033805-22-9 | 特罗司他乙酯
(Catalog# : 17011722)
特罗司他乙酯, 也称为LX 1032或LX 1606, 是一种口服血清素合成抑制剂
161715-24-8 | 泰比培南酯
(Catalog# : 17011721)
泰比培南酯,也被称为ME1211和TBM-PI, 是一种新型口腔卡宾枪抗生素。
193620-69-8 | TAS-301
(Catalog# : 17011719)
TAS-301是一种有效的、选择性的球囊冠状动脉过度拉伸损伤后的收
174634-08-3 | TAS-103
(Catalog# : 17011718)
TAS-103,也称为BMS-247615, 是一种喹啉衍生物,在小鼠和人体肿瘤模型
150080-09-4 | Talabostat甲磺酸盐
(Catalog# : 17011717)
Talabostat, 也称为PT-100,具有抗肿瘤和造血作用的二肽肽酶抑制剂。
1312691-41-0 | TAK-659盐酸盐
(Catalog# : 17011716)
TAK-659是脾脏酪氨酸激酶(syk)的抑制剂,具有潜在的抗炎、免疫和抗
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
667411-04-3 | TRPM4-IN-2
(Catalog# : 24147)
TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibi
1534-35-6 | Isolithocholic Acid
(Catalog# : 24146)
Isolithocholic acid is a bile acid that is formed via microbial metabolism of lithoch
877768-84-8 | H2-Gamendazole
(Catalog# : 24145)
H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycysti
2095432-28-1 | CPI-455 HCl
(Catalog# : 24144)
CPI-455 is a potent and selective inhibitor of KDM5 demethylases which reduces surviv
1215115-03-9 | KH-3
(Catalog# : 24143)
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC50 value
2097938-74-2 | Stafib-2
(Catalog# : 24142)
Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with
2032123-28-5 | TCRS-417
(Catalog# : 24141)
TCRS-417 (T417) is a small molecule compound capable of docking to the interface betw
1096144-06-7 | PST3 1a
(Catalog# : 24140)
PST3 1a is a Novel selective inhibitor of the N-acetylglucosamine glycosyltransferase
2225824-53-1 | YTX-465
(Catalog# : 24139)
YTX-465 is a SCD inhibitor. YTX-465 strongly reduced fatty desaturation in a concentr
944808-88-2 | CAY10566
(Catalog# : 10403)
Coming soon!