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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
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Proteases
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others
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Anilines
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Deuterated
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Pyridines
Pyrimidines
Quinolines
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中间体
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Cas号索引 1
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Cas号索引 1
1369767-20-3 | ((1S,2R)-1-(3-fluorophenyl)cyclopropane-1,2-diyl)dimethanol
(Catalog# : 202331)
我们可以提供公斤级定制合成。((1S,2R)-1-(3-fluorophenyl)cyclopropane-1,2
1393477-72-9 (free base) | Selinexor free base
(Catalog# : 2051501)
Selinexor, also known as KPT-330, is an orally bioavailable, potent and selective XPO
1330782-76-7 | Simurosertib
(Catalog# : 2041504)
Simurosertib, also known as TAK-931, is an orally bioavailable inhibitor of cell divi
1821908-48-8 (free base) | SGC2085 free base
(Catalog# : 204609)
SGC2085 is a Potent and Selective Coactivator Associated Arginine Methyltransferase 1
164991-89-3 | Segetalin B
(Catalog# : 204501)
Segetalin B is natural product isolated from Seeds of Vaccaria Segetalis. Segetalin B
1392816-46-4 | SI-113
(Catalog# : 111896)
SI113 is a specific inhibitor of the Sgk1 kinase activity, counteracting cancer cell
1350643-72-9 | IPI145中间体
(Catalog# : 196301)
186611-04-1 | SU 5214
(Catalog# : 19314)
SU 5214是酪氨酸激酶信号转导的调制器。
1423715-37-0 | Seclidemstat
(Catalog# : 192147)
Seclidemstat是一种抗肿瘤药物候选药物。
1399715-48-0 | Setafrastat
(Catalog# : 192146)
Setafrastat是一种转胺酶抑制剂和血管内皮生长因子(VEGF)促进剂。
1037210-93-7 | Saridegib
(Catalog# : 1812251)
Saridegib,又称IPI-926,是一种口服生物利用的环帕胺衍生物,是Hed
1260612-13-2 | SAR260301
(Catalog# : 1812134)
SAR260301是强有力的和选择性组 I 磷脂酰肌醇-3-激酶(PI3K)β特定抑制
1613695-14-9 | SGC-CBP30
(Catalog# : 1810244)
SGC-CBP30是CREBBP (CBP)和EP300的有效选择性抑制剂;它们是一般的转录共
1362850-20-1 | Seletalisib
(Catalog# : 1810221)
Seletalisib,也被称为UCB-5857,是一种有效的选择性PI3激酶抑制剂,
188817-13-2 | SC-560
(Catalog# : 185113)
SC-560是一种有效的具有口服活性和选择性的COX-1抑制剂。
1609452-30-3 | SEL120-34A盐酸盐
(Catalog# : 18574)
SEL120-34A是一种高效、选择性的CDK8抑制剂,活跃于AML细胞中,具有
1816294-67-3 | SR-4370
(Catalog# : 1842814)
SR-4370是一种HDAC抑制剂。
1821908-49-9 | SGC2085盐酸盐
(Catalog# : 184287)
SGC2085是一种强效的选择性共激活剂,它可以使精氨酸甲基转移酶
1222097-72-4 | S38093盐酸盐
(Catalog# : 184176)
S38093是组胺H3受体的反向激动剂。
1173022-21-3 | STO-609醋酸盐
(Catalog# : 184123)
STO-609是一种细胞渗透性抑制剂,钙/钙调蛋白依赖性激酶激酶(CaMK
1599441-71-0 | Super-TDU
(Catalog# : 18495)
Super-TDU是靶向YAP-TEADs interaction的抑制性多肽。
1253955-19-9 | (S)-(4-(3-(tert-butoxycarbonyl)-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)phenyl)methyl 2,4-dimethylbenzoate
(Catalog# : 183219)
(S)-(4-(3-(tert-butoxycarbonyl)-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)phenyl)met
132513-51-0 | (S)-2-羟基丁酸正丁酯
(Catalog# : 1712291)
(S)-2-羟基丁酸正丁酯是一种分子砌块。
14892-97-8 | SCR7 pyrazine
(Catalog# : 1712261)
SCR7吡嗪是DNA连接酶IV的小分子抑制剂,防止非同源端连接通过干扰
1333207-63-8 | SAR-7334盐酸
(Catalog# : 17101610)
SAR-7334是一种新颖的、高效的、生物可利用的TRPC6通道,打开了新
1160833-51-1 | SEN-826
(Catalog# : 1710168)
SEN-826是一种潜在抗癌剂。
1366002-50-7 | Senexin A
(Catalog# : 1710136)
Senexin A是一种强效的选择性与抑制剂(IC50 = 280 nm)。Senexin A结合
1799633-27-4 | S63845
(Catalog# : 171071)
s63845是专门结合MCL1的BH3结合槽高亲和力的小分子。s63845有效杀死
1105698-15-4 | Salermide
(Catalog# : 1791511)
salermide是一个强大的肿瘤特异性凋亡的影响长寿基因蛋白质抑制剂
1308672-74-3 | Sulfatinib
(Catalog# : 179135)
Sulfatinib是一种口服的血管内皮生长因子受体(VEGFR)1, 2,3,和成
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag