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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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DNA Damage
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Cas号索引 1
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Cas号索引 1
101526-62-9 | 司美利特盐酸盐
(Catalog# : 179830)
司美利特,也称为CK-1752,是III类抗心律失常药。它是一种选择性
168835-82-3 | SU-1498
(Catalog# : 17984)
SU-1498是一种选择性的受体酪氨酸激酶抑制剂,血管内皮生长因子
1174428-47-7 | SF2523
(Catalog# : 17918)
SF2523是一种高效、选择行的日常pan-PI3K/BRD4抑制剂。具有明显的选
1450881-55-6 | SAR-20347
(Catalog# : 1781101)
SAR-20347是一种强力JAK1和酪氨酸激酶2的双抑制剂 (TYK2).
1523406-39-4 | SAR-405
(Catalog# : 2017882)
SAR-405是一种有效且选择性的PIK3C3/Vps34抑制剂,防止自噬和协同MTO
148554-65-8 | 雷帕霉素(钠盐)
(Catalog# : 20177313)
雷帕霉素是第一个体内open-ring代谢物,不影响mTOR的雷帕霉素抑制Ch
1184843-57-9 | SAR-020106
(Catalog# : 17031004)
SAR-020106是一种 ATP -竞争性、强效和选择性的CHK1抑制剂,其IC50为1
1456632-41-9 | SH5-07
(Catalog# : 17031002)
SH5-07是一种健壮的氧肟抗酸的STAT3抑制剂,它能在体外诱导抗肿瘤
138794-73-7 | Sardomozide HCl
(Catalog# : 17030306)
Sardomozide,又名SAM486A或CGP48664,是第二代多胺合成抑制剂,它抑制
149690-05-1 | 钠盐沙库必曲
(Catalog# : 17030108)
沙库必曲,也被称为AHU377,是血管紧张素受体神经内肽酶抑制剂被
1801747-42-1 | SHP099游离
(Catalog# : 17030107)
<SHP099是强有力的,选择性,具有口服生物利用率,是一种IC50 = 0.07μM的
1431699-67-0 | 泰地唑胺杂质 A
(Catalog# : 17021402)
泰地唑胺杂质 A是磷酸四唑磷酸酯活跃的一部分,对革兰氏阳性菌
1265965-22-7 | S49076
(Catalog# : 17021309)
S49076是一种新型的、能有效抑制IC50值低于20 nmol/ L的MET、AXL / MER和
1001908-89-9 | SRT2183
(Catalog# : 17021306)
SRT2183是sirtuin子型SIRT1的小分子激活剂,目前由Sirtris制药公司开发
18883-66-4 | 链脲菌素
(Catalog# : 17011712)
链脲菌素是一种从链球菌中分离出来的甲基亚硝基脲类抗肿瘤抗生
1018899-04-1 | Sotagliflozin
(Catalog# : 17011711)
Sotagliflozin,也称为LX4211,是一种口服活性和双SGLT1 / SGLT2抑制剂,在
127254-12-0 | 西他沙星
(Catalog# : 17011706)
西他沙星是一种新型的广谱口服氟喹诺酮,它对许多革兰氏阳性、
1801747-11-4 | SHP099盐酸盐
(Catalog# : 17011704)
SHP099是一个强有力的、选择性、口服生物利用率和有效的IC50 = 0.0
1687736-54-4 | SGC707
(Catalog# : 17011702)
SGC707是一种强效、选择性和细胞活性的蛋白质精氨酸甲基转移酶3
1884220-36-3 | SBI0206965
(Catalog# : 71161)
SBI0206965是一种有效的选择性自噬激酶ULK1抑制剂。许多肿瘤变得沉
149400-88-4 | Sardomozide
(Catalog# : 17011607)
Sardomozide,也叫SAM486A或CGP48664,是一种第二代聚胺合成抑制剂,抑制
1092539-44-0 | SAR131675
(Catalog# : 17011605)
SAR131675是一种有效的选择性vegfr - 3抑制剂。
127373-66-4 | Sivelestat (ONO-5046)
(Catalog# : 16122760)
Sivelestat is a potent and selective inhibitor of neutrophil elastase with IC50 of 44
17318-31-9 | SQ22536
(Catalog# : 16122726)
SQ22536 is an inhibitor of adenylyl cyclase with an IC50 of 1.4 M. It can inhibit PGE
111540-00-2 | STA-21
(Catalog# : 16122706)
STA-21 is a selective STAT3 inhibitor.In cells, STA-21 inhibits Stat3 DNA binding act
1335106-03-0 | SR1001
(Catalog# : 6111522)
SR1001 is a selective ROR and ROR inverse agonist; suppresses TH17 cell differentiati
1324003-64-6 | S1P1 Agonist III
(Catalog# : 61119)
S1P1 Agonist III is a potent and orally active S1P1 agonist with EC50 of 18 nM; no ac
1186222-89-8 | 4SC-202
(Catalog# : 611937)
4SC-202 is an orally available potent HDACi specific for class I HDAC isoenzymes(NO H
1454585-06-8 | SR-3029
(Catalog# : 611915)
SR 3029 is a potent and highly specific CK1/CK1 inhibitor with the IC50 of 97 nM.SR-3
1456632-40-8 | SH-4-54
(Catalog# : 16071406)
SH-4-54 is a potent STAT inhibitor with KD of 300 nM and 464 nM for STAT3 and STAT5,
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag