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抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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On Sale
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技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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Cas号索引 1
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Cas号索引 1
1013101-36-4 | PF-04691502
(Catalog# : 123020)
PF-04691502 is an ATP-competitive PI3K(///)/mTOR dual inhibitor with Ki of 1.8 nM/2.1
120685-11-2 | PKC412
(Catalog# : 123013)
PKC412 is a broad spectrum protein kinase inhibitor; inhibits conventional PKC isofor
155148-31-5 | Plerixafor octahydrochloride
(Catalog# : 123004)
Plerixafor octahydrochloride is a chemokine receptor antagonist for CXCR4 and CXCL12-
1290543-63-3 | PF-3084014
(Catalog# : 122950)
PF-3084014 is a novel -secretase inhibitor that reduces amyloid-beta (Abeta) producti
130663-39-7 | PD 123319
(Catalog# : 122903)
PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of
123464-89-1 | PNU-282987
(Catalog# : 122827)
PNU-282987 is a selective 7 nicotinic acetylcholine receptor(7 nAChR) agonist with Ki
171228-49-2 | Posaconazole
(Catalog# : 122815)
Posaconazole is a broad-spectrum, second generation, triazole compound with antifunga
196868-63-0 | PQ401
(Catalog# : 122806)
PQ401, a selective insulin-like growth factor-1 receptor blocker, is a novel diarylur
1046787-18-1 | PKC-IN-1
(Catalog# : 122520)
PKC-IN-1 is a poent PKC beta II inhibitor with Ki of 14.9 nM; compound example H6 fro
1082744-20-4 | PF-04447943
(Catalog# : 122515)
PF-04447943 is a potent, selective brain penetrant PDE9 inhibitor (Ki of 2.8, 4.5 and
1035979-44-2 | P005672 hydrochloride
(Catalog# : 122302)
P005672 hydrochloride is used for antibacterial/anti-inflammatory acne treatment.
124436-59-5 | Pirodavir
(Catalog# : 122216)
Pirodavir is the prototype of a novel class of broad-spectrum antipicornavirus compou
1173204-81-3 | PKI-402
(Catalog# : 121421)
PKI-402 is a potent dual pan-PI3K/mTOR inhibitor targeting PI3K/// and mTOR with IC50
150399-23-8 | Pemetrexed disodium
(Catalog# : 120704)
Coming soon!
183322-45-4 | PD153035 Hcl
(Catalog# : 111003)
PD153035 Hcl is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM an
1194961-19-7 | PRT-060318
(Catalog# : 110904)
PRT-060318 is a novel selective inhibitor of the tyrosine kinase Syk, as an approach
1334513-02-8 | propan-2-yl (2S)-2-[[(2,3,4,5,6-pentafluorophenoxy)-phenoxyphosphoryl]amino]propanoate
(Catalog# : 102302)
Coming soon!
1527473-33-1 | PF06447475
(Catalog# : 101601)
PF-06447475 is a highly potent, selective, brain penetrant LRRK2 inhibitor with IC0 o
152811-62-6 | Piboserod
(Catalog# : 92301)
Piboserod , also known as SB-207266, is a selective 5-HT4 receptor antagonist which w
1253799-29-9 | phenyl 2-(benzyloxy)-3-(dibenzylamino)-5-fluoro-6-methylbenzoate
(Catalog# : 91806)
Coming soon!
144010-02-6 | 3-Piperazinobenzisothiazole Hydrochloride
(Catalog# : 91409)
The related APILurasidone hydrochlorideThe related intermediates4-(1,2-Benzothiazol-3
122323-87-9 | Piperazin-2-ylmethanol dihydrochloride
(Catalog# : 81821)
Coming soon!
122323-88-0 | Piperazine-2-Carboxylic Acid Methyl Ester Dihydrochloride
(Catalog# : 81817)
Coming soon!
137071-32-0 | Pimecrolimus
(Catalog# : 81302)
Pimecrolimus is an immunophilin ligand, which binds specifically to the cytosolic rec
147526-32-7 | Pitavastatin Calcium
(Catalog# : 81301)
Pitavastatin is a member of the blood cholesterol lowering medication class of statin
1197160-78-3 | PKI-587
(Catalog# : 73109)
PKI-587 is a potent inhibitor to PI3K-, PI3K-, and mTOR (FRAP) with IC50 of 0.4 nM, 5
1263-89-4 | Paromomycin Sulfate
(Catalog# : 52815)
Paromomycin Sulfate is an aminoglycoside antibiotics inhibiting protein synthesis in
1029044-16-3 | Pexidartinib
(Catalog# : 52753)
pexidartinib is acapsule formulation containing a small-molecule receptor tyrosine ki
1415562-82-1 | PF-543
(Catalog# : 52740)
PF-543 is a novel cell-permeant inhibitor of SphK1 with a Ki of 3.6 nM, PF-543 is sph
1190307-88-0 | PSI-7977
(Catalog# : 52718)
PSI-7977(sofosbuvir) is an investigational nucleotide analog for treatment of chronic
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
| MD-43
(Catalog# : 25016)
MD-43是MCT4的强效选择性降解剂。
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
2247396-91-2 | HC-5404 抑制剂
(Catalog# : 25001)
HC-5404 是一种新型、高选择性、有效的PERK抑制剂。
3034479-99-4 | HC-5404-FU
(Catalog# : 24112)
HC-5404-FU 是一种新型、高选择性、有效的PERK抑制剂。
2309409-79-6 | CMP-5 2HCl
(Catalog# : 24161)
CMP-5 is a potent, specific, and selective PRMT5 inhibitor, while displays no activit
2630378-05-9 | Wu-5
(Catalog# : 24160)
Wu-5 is a USP10 inhibitor that can inhibit FLT3 and AMPK pathways, induce FLT3-ITD de
890764-36-0 | VU-29
(Catalog# : 24159)
VU 29 is a potent allosteric potentiator at the rat mGlu5 receptor (EC50 = 9 nM); bin
1221186-52-2 | ML-202
(Catalog# : 24158)
ML-202 is an activator of pyruvate kinase M2 (PKM2).
921193-28-4 | BTA-EG4 hydrate
(Catalog# : 24157)
BTA-EG4 is a catalase-amyloid interaction inhibitor, which can significantly enhance
2415281-52-4 | CYD19
(Catalog# : 24156)
CYD19 is a potent Snail/HDAC dual target inhibitor.