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Cytoskeletal Signaling
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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
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Ubiquitin
Neuronal Signaling
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Pyrimidines
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Cas号索引 1
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Cas号索引 1
1338540-63-8 | OTS514
(Catalog# : 17031015)
OTS514是一种高效的TOPK(T-LAK胞起源蛋白激酶)抑制剂,IC50值为2.6 nM。
167305-00-2 | 奥马曲拉
(Catalog# : 17030903)
奥马曲拉是一种新型的抗高血压药,可抑制中性内肽酶(NEP)和血管
1026791-61-6;100044-96-0 | Org-26576
(Catalog# : 17021328)
Org-26576是一种AMPA谷氨酸受体调制器,可能用于治疗抑郁症和注意
14698-29-4 | Oxolinic acid
(Catalog# : 16122720)
Oxolinic acid is a quinolone antibiotic, inhibiting the enzyme DNA gyrase and DNA syn
1357470-29-1 | ON123300
(Catalog# : 16122712)
ON123300 is a potent and multi-targeted kinase inhibitor with IC50 of 3.9 nM, 5 nM, 2
1640292-55-2 | Oclacitinib
(Catalog# : 16122705)
Oclacitinib is a novel inhibitor of JAK family members with IC50 ranging from 10 to 9
1801787-56-3 | OICR-9429
(Catalog# : 6111010)
OICR-9429 is a novel small-molecule antagonist of the Wdr5-MLL interaction with IC50
1404231-34-0 | ON 146040
(Catalog# : 611901)
ON 146040 is the first dual PI3K and BCR-ABL inhibitor that targets the STAT3 and STA
193153-04-7 | OtaMixaban
(Catalog# : 16070915)
OtaMixaban
171099-57-3 | Oritavancin
(Catalog# : 16070815)
Oritavancin, also known as LY333328, is a novel semisynthetic glycopeptide antibiotic
1330633-98-1(free base) | ON-01911.Na
(Catalog# : 1662310)
ON-01911.Na is a non-ATP-competitive inhibitor ofPLK1.
183321-86-0 | OSI-420(Desmethyl Erlotinib)
(Catalog# : 166215)
OSI-420 is the active metabolite of Erlotinib which is an orally active EGFR tyrosin
1351635-67-0 | ONO4059-Analog
(Catalog# : 652602)
ONO4059-Analog(CAS#1351635-67-0)is a potent and selective BTK inhibitor.
192564-14-0 | Oritavancin(OC)
(Catalog# : 42510)
Oritavancin (INN, also known as LY333328, Orbactiv) is a novel semisynthetic glycopep
1297538-32-9 | ODM-201(BAY-1841788)
(Catalog# : 123101)
ODM-201(also known as BAY-1841788)is a novel, nonsteroidal, orally active AR inhibito
1086062-66-9 | Omipalisib(GSK2126458,GSK458)
(Catalog# : 121429)
GSK2126458 is a highly selective and potent inhibitor of PI3K with Ki of 0.019 nM/0.1
175135-47-4 | O4I1
(Catalog# : 120813)
O4I1 is as a potent Oct3/4 inducer.
165682-93-9 | O4I2
(Catalog# : 120812)
O4I2 is a potent Oct3/4 inducer in various human cell lines including human fibroblas
132539-06-1 | Olanzapine
(Catalog# : 120415)
Coming soon!
10300-27-3 | 3’-OMe Guanosine
(Catalog# : 91416)
3-OMe Guanosine CAS#10300-27-3
14466-21-8 | 5-Oxopyrrolidine-3-carboxamide
(Catalog# : 90110)
Coming soon!
1190890-11-9 | 1-O-tert-butyl 2-O-methyl (2R)-pyrrolidine-1,2-dicarboxylate
(Catalog# : 90101)
Coming soon!
1280210-80-1 | Omarigliptin intermediate 2
(Catalog# : 82722)
Coming soon!
1251903-83-9 | 1-O-tert-butyl 3-O-methyl (3R)-piperazine-1,3-dicarboxylate,hydrochloride
(Catalog# : 81819)
Coming soon!
125700-67-6 | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium Tetrafluoroborate
(Catalog# : 81717)
Coming soon!
1338545-07-5 | OTS964
(Catalog# : 51507)
TOPK (TClymphokine-activated killer cellCoriginated protein kinase) is highly and fre
1637677-22-5 | Povorcitinib
(Catalog# : 24079)
Povorcitinib is a Janus kinase inhibitor that also displays anti-inflammatory activit
1232841-78-9 | PBT434 氢溴酸盐
(Catalog# : 24067)
PBT434, also known as ATH434 , is a novel, brain-penetrant, inhibitor of α-synuclein
1628287-16-0 | Pico145
(Catalog# : 24037)
Pico145 (HC-608) is a remarkable inhibitor ofTRPC1/4/5channels, inhibits (−)-engler
1362911-19-0 | proTAME
(Catalog# : 24056)
ProTAME 一种APC/C 的小分子抑制剂。
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag