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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
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Ubiquitin
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others
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Deuterated
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Pyrimidines
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Cas号索引 1
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Cas号索引 1
1693734-80-3 | NXP-800 ( CCT361814 )
(Catalog# : 233141)
NXP800 是一种口服小分子热休克因子 1 (HSF1) 通路抑制剂。 NXP800 可
168021-79-2 | NXY-059 ( Disufenton Sodium )
(Catalog# : 52014)
Disufenton sodium (NXY-059) 是神经保护剂phenylbutynitrone的衍生物,具有极
1628263-77-3 | N-(6-bromo-2-ethyl-8-methylimidazo[1,2-a]pyridin-3-yl)formamide
(Catalog# : 20402)
1628263-96-6 | N-(6-bromo-2-ethyl-8-methylimidazo[1,2-a]pyridin-3-yl)-N-methylformamide
(Catalog# : 20401)
1335241-44-5 | N,N-DIETHYL-2,6-CIS-DIMETHYLPIPERIDINIUM IODIDE
(Catalog# : G20383)
1402837-78-8 (free base) | Navoximod free base
(Catalog# : 20290)
1401728-56-0 | NE 52-QQ57
(Catalog# : 21233)
NE52-QQ57 is an orally available GPR4 antagonist with an IC50 of 70 nM. NE 52-QQ57 si
1783816-74-9 | NVS-PAK1-1
(Catalog# : 21231)
NVS-PAK1-1 is a a specific allosteric PAK1 inhibitor.
1613220-15-7 | Niraparib tosylate hydrate
(Catalog# : 2021115)
Niraparib, also know as MK-4827, is an inhibitor of poly (ADP-ribose) polymerase (PAR
1346133-39-8 | N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
(Catalog# : 2062032)
120173-57-1 | N-Fmoc-O-[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-α-D-galactopyranosyl]-L-serine
(Catalog# : 2061601)
1019115-13-9 | N-benzyl-2,4-dichloropyrimidine-5-carboxamide
(Catalog# : 197101)
1263373-43-8 | NVP-2
(Catalog# : 193205)
NVP-2是细胞周期蛋白依赖性激酶CDK9的抑制剂。
1566-81-0 | NS-1652
(Catalog# : 19361)
NS-1652是一种阴离子电导抑制剂。
1434639-57-2 | ND-646
(Catalog# : 191102)
ND-646是ACC酶ACC1和ACC2的变构抑制剂,可阻止ACC亚基二聚化,在体内
1434635-54-7 | ND-630
(Catalog# : 19133)
ND-630,也称为GS-0976, NDI-010976和firsocostat, 是一种有效的ACC抑制剂。
1448232-80-1 | Naquotinib游离
(Catalog# : 1812297)
Naquotinib,又称ASP8273,是一种口服、不可逆、第三代、突变选择、
1208315-24-5 | N6022
(Catalog# : 1811304)
N6022是一种有效、选择性、可逆性和有效性的s -亚硝基谷胱甘肽还
1253584-84-7 | NMS-E973
(Catalog# : 1810293)
NMS-E973是一种新型、选择性和强效的热休克蛋白90 (Hsp90)抑制剂。
153587-01-0 | NS1619
(Catalog# : 1810227)
NS1619是一种Bkca开启工具或大电导Ca2+活化钾(Bkca, KCa1.1)通道激活器
1452458-86-4 | Nacubactam
(Catalog# : 185169)
Nacubactam, 也称为RG-6080, FPI-1459, 和OP-0595, 是一种β-内酰胺酶抑制剂
108852-90-0 | Nemorubicin
(Catalog# : 185167)
Nemorubicin,又名PNU152243A,是一种不同于其母体药物的doxorubicin衍生
152946-68-4 | Nolatrexed盐酸盐
(Catalog# : 185166)
Nolatrexed,也叫AG337,是一种具有潜在抗癌活性的胸腺嘧啶合成酶抑
1773489-72-7 | Nidufexor
(Catalog# : 184288)
Nidufexor是一个法呢醇X受体(FXR)激动剂。
1422144-42-0 | Netarsudil(Mesylate)
(Catalog# : 712181)
Netarsudil( AR-11324) is a Rho-associated protein kinase inhibitor. Netarsudil is pot
1140844-63-8 | nor-NOHA醋酸盐
(Catalog# : 1710169)
nor-NOHA是一种强效、选择性、竞争性、以及精氨酸酶的高亲和力抑
1262417-51-5 | NMS-P118
(Catalog# : 17101311)
NMS-P118是一种有效的、可口服、高选择性PARP-1抑制剂具有优良的AD
1508250-71-2 | Nazartinib (EGF816)
(Catalog# : 1781004)
Nazartinib,也被称为EGF816,是一种口服可用,不可逆转的、第三代、
1254032-66-0 | Netarsudil
(Catalog# : 1781001)
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1676893-24-5 | NSC781406
(Catalog# : 20178810)
NSC781406是一种高效针对PI3K的IC50为2 nM的PI3K和mTOR抑制剂。
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag