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首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
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Cytoskeletal Signaling
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TGF-beta/Smad
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Cas号索引 1
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Cas号索引 1
1393124-08-7 | PF-06291874
(Catalog# : 185154)
PF-06291874是一种胰高血糖素受体拮抗剂,对2型糖尿病患者有效。
1353552-97-2 | Poseltinib
(Catalog# : 185153)
Poseltinib, 也称为HM-71224和LY3337641,一种酪氨酸激酶抑制剂。
1353900-92-1 | Pibrentasvir
(Catalog# : 185148)
Pibrentasvir,也被称为ABT-530,是一种蛋白酶抑制剂,可用于治疗丙
172889-27-9 | PP2
(Catalog# : 185146)
PP2,也被称为AG 1879,是一种经常被用于癌症研究的物质,作为src
172889-26-8 | PP1
(Catalog# : 185145)
PP1是一种有效的选择性Src家族蛋白酪氨酸激酶抑制剂。
146949-21-5 | Pocapavir
(Catalog# : 185144)
Pocapavir,也被称为SCH -48973和V-073,是一种强效、选择性的抗肠道病
1702967-37-0 | PSMA617 TFA
(Catalog# : 185143)
PSMA-617是一种配体,用于制造177Lu -PSMA-617,这是一种用于对抗癌症
1472611-44-1 | Pyridostatin TFA盐
(Catalog# : 185142)
Pyridostatin在细胞中稳定G-四链体(G4s),并通过DNA双链断裂(DSB)的形成
1811510-56-1 | PF-06260933
(Catalog# : 18544)
PF-06260933是一种有效且高选择性MAP4K4抑制剂。
1627929-55-8 | PLX51107
(Catalog# : 184285)
PLX51107是一种高效、选择性的BRD4抑制剂或BET抑制剂,其体外和体内
171179-06-9 | PD 158780
(Catalog# : 184284)
PD 158780是表皮生长因子受体(EGFR) (IC50为0.08 nM)的酪氨酸激酶活性的
1997387-43-5 | PZM21
(Catalog# : 184162)
PZM21是强有力Gi活化剂,对μOR和最小β-arrestin-2具有特殊选择性的补
1627607-87-7 | PFI-2盐酸盐
(Catalog# : 184106)
在其他甲基转移酶和其他非表观遗传靶点上,PFI-2是一种具有IC50为
198474-05-4 | PF-0684000
(Catalog# : 184318)
PF-0684000,也称为EOS200271,是强有力的IDO-1抑制剂(IC50 0.15μM)。PF-06
1467057-23-3 | PF-06409577
(Catalog# : 18434)
PF-06409577是一种有效和具有选择的5腺苷酸活化蛋白激酶(AMPK)激活剂
1802929-43-6 | PRN-1371
(Catalog# : 17101614)
PRN-1371是一种共价键,不可逆的,高选择性的纤维母细胞生长因子
1293395-67-1 | PF-5006739
(Catalog# : 17101612)
PF-5006739是一种有效的CK1δ/ε抑制剂。PF-5006739对阿片类药物具有药
1383719-97-8 | PF-04628935
(Catalog# : 17101611)
PF-04628935是一种有效的关于胃肽感受器的拮抗激动剂,生长激素促
1210608-43-7 | PIM447
(Catalog# : 1710134)
PIM447,也称为lgh447,是一种有效的Moloney小鼠白血病(PIM)1, 2,和
179474-81-8 | Pyridostatin TFA盐
(Catalog# : 1791517)
Pyridostatin稳定G-四链体(G4S)在细胞和诱导引起的DNA双链断裂形成
179474-85-2 | 琥珀酸普卡比利
(Catalog# : 1791516)
琥珀酸普卡比利,也称为r-108512,是一种选择性、高亲和力的5-羟
104632-25-9 | 盐酸普拉克索
(Catalog# : 1791510)
普拉克索是一个GαI-联多巴胺受体D2、D3和D4受体激动剂。它是相对
1435467-38-1 | PF-06281355
(Catalog# : 1791312)
PF-06281355,也称为PF-1355,是一种口服有效的、选择性的,有效的机
1235481-43-2 | P7C3-OMe
(Catalog# : 179116)
P7C3-OMe,也称为(R)- P7C3-OMe,是P3C3-A20和P7C3的模拟。减轻C57BL/6J小
1962928-21-7 | PF-CBP1 游离
(Catalog# : 179113)
PF-CBP1,也称为 PF06670910,是强效、高选择性的CREB结合蛋白布罗莫
1817626-54-2 | PF-06650833
(Catalog# : 17988)
PF-06650833是一种白细胞介素-1受体相关激酶4 (IRAK4)抑制剂。IRAK4位于
1234015-55-4 | Prexasertib 甲磺酸
(Catalog# : 17986)
Prexasertib也称为LY2606368,是一种有效,具有选择性的Chk1/Chk2抑制剂
192705-79-6 | PD166866
(Catalog# : 178814)
PD166866有明显的抗增殖作用。
135729-61-2 | 帕洛诺司琼
(Catalog# : 2017080119)
帕洛诺司琼是一种5-HT3拮抗剂,用于预防和治疗化疗引起的恶心和
1776112-90-3 | PF-06747775
(Catalog# : 175161)
PF-06747775(PF06747775;CAS 1776112-90- 3)是表皮生长因子受体(EGFR)突变体T7
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
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GP130 modulator-1 (compound A33) 是一种GP130信号通路调节剂。GP130 modulato
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(Catalog# : 25061)
TGN 073 is a facilitator of aquaporin-4 (AQP4), an astroglial water channel. The rats
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MFI8 is a Mitochondrial Fusion Inhibitor
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(Catalog# : 25055)
BAY-593 is an orally active inhibitor of geranylgeranyltransferase-I (GGTase-I) that
188425-85-6 | Boscalid
(Catalog# : 25054)
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(Catalog# : 25053)
SABA1 is an antibacterial agent against Pseudomonas aeruginosa and Escherichia coli.