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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
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others
PROTAC
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Amino Acids
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Deuterated
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Cas号索引 1
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Cas号索引 1
1672665-49-4 | PT2385
(Catalog# : 1812135)
PT2385是一种口服活性小分子缺氧诱导因子(HIF)-2alpha抑制剂,具有潜
133413-70-4 | PF 1022A
(Catalog# : 1811232)
PF1022A是一种新型的驱虫药,与嗜乳激素样跨膜受体结合,对线虫
146464-95-1 | 普拉曲沙
(Catalog# : 1811221)
普拉曲沙是二氢叶酸还原酶(DHFR)的一种叶酸模拟抑制剂,对叶酸还
1037589-69-7 | PF-05231023
(Catalog# : 1811162)
PF-05231023是一种长效FGF21仿生产品。PF-05231023可以减轻非人类灵长类
1311174-68-1 | PH-002
(Catalog# : 1810234)
PH-002是一种新型的载脂蛋白(apo) E4分子内区域相互作用的神经细胞
1513857-77-6 | Pemigatinib (INCB054828)
(Catalog# : 1810164)
Pemigatinib是一种酪氨酸激酶抑制剂,也是一种抗肿瘤药物候选药物
1022899-36-0 | PCI-33380
(Catalog# : 18943)
PCI-33380是基于ibrutinib支架设计的,已被用于细胞和体内研究,证实
1613373-33-3 | PCO371
(Catalog# : 187125)
PCO371是一种有效的、选择性的PTHR1激动剂,用于治疗低甲状旁腺功
1927857-61-1 | PQR530
(Catalog# : 18756)
PQR530是一种高效的日常pan-PI3K/mTORC1/2抑制剂。
1269662-73-8 | Pyrotinib
(Catalog# : 18731)
Pyrotinib,又称SHR -1258,是一种口服生物利用的双激酶抑制剂,是表
1268244-85-4 | PX20606反式消旋体
(Catalog# : 186274)
PX20606, 也称为PX-102, 是一种FXR激动剂。
1394033-54-5 | PF-05180999
(Catalog# : 186153)
PF-05180999是一个强有力的和选择性PDE2a抑制剂(PDE2a的IC50 = 0.001μM,
1428333-96-3 | Pritelivir甲磺酸盐
(Catalog# : 186152)
Pritelivir,又名AIC-316和BAY 57-1293,是一种有效的螺旋酶抑制剂。
1446261-44-4 | Pamiparib
(Catalog# : 185233)
Pamiparib是高选择性PARP-1/2抑制剂。临床试验中表现出良好的抗肿瘤
1005168-10-4 | PAC 14028
(Catalog# : 185223)
PAC-14028是高效的选择性的瞬时受体电位香草酸亚型1 (TRPV1) 拮抗剂
1402727-29-0 | PE859
(Catalog# : 185157)
PE859是一个强有力的IC50值分别为0.66和1.2μM的tau和Aβ聚合抑制剂。
190383-31-4 | PD 168 077
(Catalog# : 185156)
PD168077是一种多巴胺D4受体激动剂,对记忆巩固有促进作用。
1622291-66-0 | PF-06462894
(Catalog# : 185155)
PF-06462894是一种形态学上的mGlu5 (mGlu5 Ki = 6nm)。
1393124-08-7 | PF-06291874
(Catalog# : 185154)
PF-06291874是一种胰高血糖素受体拮抗剂,对2型糖尿病患者有效。
1353552-97-2 | Poseltinib
(Catalog# : 185153)
Poseltinib, 也称为HM-71224和LY3337641,一种酪氨酸激酶抑制剂。
1353900-92-1 | Pibrentasvir
(Catalog# : 185148)
Pibrentasvir,也被称为ABT-530,是一种蛋白酶抑制剂,可用于治疗丙
172889-27-9 | PP2
(Catalog# : 185146)
PP2,也被称为AG 1879,是一种经常被用于癌症研究的物质,作为src
172889-26-8 | PP1
(Catalog# : 185145)
PP1是一种有效的选择性Src家族蛋白酪氨酸激酶抑制剂。
146949-21-5 | Pocapavir
(Catalog# : 185144)
Pocapavir,也被称为SCH -48973和V-073,是一种强效、选择性的抗肠道病
1702967-37-0 | PSMA617 TFA
(Catalog# : 185143)
PSMA-617是一种配体,用于制造177Lu -PSMA-617,这是一种用于对抗癌症
1472611-44-1 | Pyridostatin TFA盐
(Catalog# : 185142)
Pyridostatin在细胞中稳定G-四链体(G4s),并通过DNA双链断裂(DSB)的形成
1811510-56-1 | PF-06260933
(Catalog# : 18544)
PF-06260933是一种有效且高选择性MAP4K4抑制剂。
1627929-55-8 | PLX51107
(Catalog# : 184285)
PLX51107是一种高效、选择性的BRD4抑制剂或BET抑制剂,其体外和体内
171179-06-9 | PD 158780
(Catalog# : 184284)
PD 158780是表皮生长因子受体(EGFR) (IC50为0.08 nM)的酪氨酸激酶活性的
1997387-43-5 | PZM21
(Catalog# : 184162)
PZM21是强有力Gi活化剂,对μOR和最小β-arrestin-2具有特殊选择性的补
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
667411-04-3 | TRPM4-IN-2
(Catalog# : 24147)
TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibi
1534-35-6 | Isolithocholic Acid
(Catalog# : 24146)
Isolithocholic acid is a bile acid that is formed via microbial metabolism of lithoch
877768-84-8 | H2-Gamendazole
(Catalog# : 24145)
H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycysti
2095432-28-1 | CPI-455 HCl
(Catalog# : 24144)
CPI-455 is a potent and selective inhibitor of KDM5 demethylases which reduces surviv
1215115-03-9 | KH-3
(Catalog# : 24143)
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC50 value
2097938-74-2 | Stafib-2
(Catalog# : 24142)
Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with
2032123-28-5 | TCRS-417
(Catalog# : 24141)
TCRS-417 (T417) is a small molecule compound capable of docking to the interface betw
1096144-06-7 | PST3 1a
(Catalog# : 24140)
PST3 1a is a Novel selective inhibitor of the N-acetylglucosamine glycosyltransferase
2225824-53-1 | YTX-465
(Catalog# : 24139)
YTX-465 is a SCD inhibitor. YTX-465 strongly reduced fatty desaturation in a concentr
944808-88-2 | CAY10566
(Catalog# : 10403)
Coming soon!