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Angiogenesis
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Cytoskeletal Signaling
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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
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Metabolism
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Cas号索引 2
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Cas号索引 2
23687-26-5 | 6-氨基异喹啉
(Catalog# : S-203043)
255713-47-4 | A-119637
(Catalog# : 204603)
A-119637 is a novel, selective and potent alpha1D antagonist.
2296729-00-3 | AMG-510
(Catalog# : 112193)
AMG-510 is a potent KRAS G12C covalent inhibitor. AMG-510 selectively targets the KRA
2252403-56-6 | AMG-510 racemate
(Catalog# : 112194)
AMG-510 is a potent KRAS G12C covalent inhibitor. AMG-510 selectively targets the KRA
246529-22-6 | Aramchol
(Catalog# : 6111903)
From:https://galmedpharma.com/about-aramchol/Aramchol(arachidyl amido cholanoic aci
2064292-12-0 | A1874
(Catalog# : 193287)
A1874是一种以核桃仁为基础的,BRD4降解的丙交酯,诱导BRD4在细胞
2196204-23-4 | AZ1495
(Catalog# : 193222)
AZ1495是一种有效且具有选择性的IRAK4抑制剂。
2101291-07-8 | AZD-0284
(Catalog# : 19365)
AZD-0284是一种强有力的、有选择性的反兴奋剂,可以潜在治疗核受
202463-68-1 | AM281
(Catalog# : 19315)
AM281是一种合成大麻素CB1受体拮抗剂。
2097416-76-5 | AZD0364
(Catalog# : 192275)
AZD0364是一种用于治疗癌症的ERK1和/或ERK2激酶。ERK1和ERK2激酶是广泛
2248003-60-1 | AZD3229
(Catalog# : 191287)
AZD3229是治疗胃肠道间质瘤的一种有效的pan-kit突变抑制剂。AZD3229在
2057509-72-3 | AZD4573
(Catalog# : 191212)
AZD-4573是一种选择性的丝氨酸/苏氨酸依赖性激酶9 (CDK9)的短期抑制
289893-26-1 | Arimoclomol maleate
(Catalog# : 188281)
Arimoclomol,也被称为BRX-220,能够潜在有用的治疗Niemann-Pick疾病C型
22816-60-0 | A22盐酸盐
(Catalog# : 186211)
A22是一种MreB的抑制剂,是一种类似actin样的细菌蛋白,已经被证明
2095393-15-8 | ARQ-531
(Catalog# : 185176)
ARQ-531是一种具有潜在抗肿瘤活性的有效的口服BTK抑制剂。
2089288-03-7 | AZD1390
(Catalog# : 18541)
AZD1390是一种强效和选择性的ATM抑制剂,适合治疗颅内恶性肿瘤,
252017-04-2 | AZD7545
(Catalog# : 179136)
AZD7545是丙酮酸脱氢酶激酶2抑制剂(pdhk2)(对6.4nm IC50值)用于治
2091134-35-7 | AZD4205
(Catalog# : 20178710)
AZD4205是一种高效JAK1-选择性激酶抑制剂,拥有优秀的临床前药代动
2002381-31-7 | APS-2-79
(Catalog# : 16122775)
APS-2-79 is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antago
229961-45-9 | AGN 194310
(Catalog# : 6111516)
AGN 194310(VTP-194310) is a potent and selective pan-RARs agonist with Kd values of 3
2002381-25-9 | APS-2-79
(Catalog# : 6111501)
APS-2-79 is an antagonist of MEK phosphorylation by RAF through direct binding of the
21230-50-2 | 3-aMino-1-Methyl-1H-pyrazole-4-carbonitrile
(Catalog# : 6111001)
3-aMino-1-Methyl-1H-pyrazole-4-carbonitrile 21230-50-2
2070009-66-2 | A-674563 hydrochloride
(Catalog# : 611802)
A-674563 hydrochloride is a potent selective Akt1 inhibitor with an IC50 of 14 nM; al
297730-17-7 | AVN944
(Catalog# : 022201)
AVN944 is an orally available, synthetic small molecule with potential antineoplastic
252025-52-8 | Adjudin
(Catalog# : 122824)
Adjudin is a drug which is under development as a potential non-hormonal male contrac
249921-19-5 | Anamorelin
(Catalog# : 122407)
Anamorelin is a synthetic orally active ghrelin receptor agonist which is under devel
23828-92-4 | Ambroxol hydrochloride
(Catalog# : 120408)
Coming soon!
22059-21-8 | 1-aminocyclopropanecarboxylic acid
(Catalog# : 110211)
Coming soon!
256925-03-8 | AL 082D06
(Catalog# : 101921)
AL 082D06(D-06) is the first selective, nonsteroidal glucocorticoid receptor (GR) ant
219766-25-3 | ANA-12
(Catalog# : 101910)
ANA-12 is aTrkB receptor antagonist, which showed direct and selective binding to Trk
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag