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Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
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Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
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Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
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others
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Antibody-drug Conjugate/ADC Related
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
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On Sale
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Cas号索引 2
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Cas号索引 2
2086772-26-9 | JNJ-64619178
(Catalog# : 193292)
JNJ-64619178是一种候选的抗癌药物。
259869-55-1 | JWH-133
(Catalog# : 6111109)
JWH 133 is a potent CB2 selective agonist with Ki of 3.4 nM, 200-fold selective over
202475-60-3 | JANEX-1
(Catalog# : 52220)
Janex-1 is a cell-permeable, reversible, potent, ATP-competitive, and specific inhibi
2416873-83-9 | KB-0742
(Catalog# : 24040)
KB-0742 是一种有效的,选择性的和具有口服活性的 CDK9 抑制剂。
2416874-75-2 | KB-0742 dihydrochloride
(Catalog# : 24020)
KB-0742 是一种有效的、选择性的、口服生物可利用的 CDK9 小分子抑
2082765-42-0 | KP-302 ( Synonyms: Lucid-21-302 ; Lucid-MS )
(Catalog# : 20641)
KP-302 ( Synonyms: Lucid-21-302 ; Lucid-MS ) 是一种蛋白质精氨酸脱亚胺酶的
2446480-97-1 | KSQ-4279
(Catalog# : 20472)
KSQ-4279 is a USP1 and PARP inhibitor. KSQ-4279 showed anti-proliferative effects in
2226664-93-1 | KY19382
(Catalog# : L20334)
KY19382 is an orally active dual inhibitor of CXXC5-DVL and GSK3β
228559-41-9 | Ki8751
(Catalog# : 17022703)
Ki8751是一种强力的、选择性的VEGFR- 2酪氨酸激酶(IC50 = 0.9 nM)的抑制
286370-15-8 | KRN 633
(Catalog# : 51912)
KRN 633 is an ATP-competitive inhibitor ofVEGFR1/2/3withIC50of 170 nM/160 nM/125 nM,
2247995-37-3 | Lazertinib mesylate
(Catalog# : 25052)
Lazertinib是一种口服的第三代选择性表皮生长因子受体(EGFR)抑制
2688040-45-9 | Lirafugratinib HCl
(Catalog# : 24113)
Lirafugratinib, also known as RLY-4008, is a tyrosine kinase inhibitor with potential
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
2834106-06-6 | LTGO-33
(Catalog# : 24103)
LTGO-33 is a selective, state-independent, and potent preclinical small molecule NaV1
2719793-90-3 | Lunresertib
(Catalog# : 24080)
Lunresertib, alsop known as RP-6306, is a potent and selective PKMYT1 inhibitor (IC50
2495096-26-7 | lartesertib
(Catalog# : 24066)
Lartesertib (M4076) is a potent inhibitor of serine/threonine protein kinase ATM (ext
297180-15-5 | Lipofermata
(Catalog# : 24030)
Lipofermata is a fatty acid transport protein 2(FATP2)inhibitor. Lipofermata shows fa
2568608-48-8 | LY3522348
(Catalog# : 20577)
244240-24-2 | LFM-A13
(Catalog# : 20438)
LFM-A13 is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK). LF
2375815-63-5 | LY-3475070
(Catalog# : 21244)
LY-3475070 is a potent and selective CD73 Inhibitor with IC50 of 28 nM. LY3475070 Alo
2097938-59-3 | Lerociclib HCl (G1T38 HCl)
(Catalog# : 2073106)
Lerociclib HCl (G1T38 dihydrochloride)是一种分化型口服CDK4 / 6抑制剂,对
2055050-87-6 | LAU159
(Catalog# : 2071505)
LAU159 is a potent modulator of α6β3γ2 GABAA receptor.
294623-49-7 | L006235
(Catalog# : 2061307)
L006235 is a potent, reversible cathepsin K inhibitor (IC50 = 0.25 nM) that displays
2274819-46-2 | LUT-014
(Catalog# : 2042701)
LUT-014 is a B-Raf Inhibitor. Leveraging the paradoxical effect of B-Raf Inhibitors,
2135600-76-7 | LSZ102
(Catalog# : 2041502)
LSZ102 is a potent ERα antagonist and degrader. LSZ102 showed ERα degradation IC50
2173037-97-1 | LY2794193
(Catalog# : 193262)
LY2794193是一种高效选择性的mGlu3受体激动剂。
2166616-75-5 | LY-3381916
(Catalog# : 193123)
LY-3381916是一种强效的、选择性的、脑透性的IDO1活性抑制剂,与缺
245075-84-7 | LR-90
(Catalog# : 19364)
LR-90是一种晚期糖基化终产物(AGE)抑制剂,可抑制人单核细胞的炎
2222755-14-6 | LOXO-292
(Catalog# : 192195)
LOXO-292 (ARRY-192)是一种口服和临床开发的选择性研究药物,用于治
292632-98-5 | L685458
(Catalog# : 186156)
L685458是一个强有力的和选择性γ分泌酶抑制剂。
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
2991818-13-2 | MGD-28
(Catalog# : 25073)
MGD-28 is a potent molecular glue degrader that demonstrates significant in vitro eff
| TG101209 analog 1
(Catalog# : 25072)
TG101209 analog 1 (Compound 8h) is an inhibitor of BUB1B with an IC50 of 10.36 μ M.
2170729-29-8 | AT-007
(Catalog# : 25071)
AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase in
1358751-06-0 | TAK-653
(Catalog# : 25070)
TAK-653 is a novel AMPA receptor potentiator, strictly potentiating a glutamate-induc
1801344-14-8 | Emavusertib
(Catalog# : 25069)
Emavusertib, also known as CA-4948 is a potent IRAK4/FLT3 inhibitor with anti-tumor a
1305267-37-1 | Roginolisib
(Catalog# : 25068)
Roginolisib, also known as MSC2360844 and IOA-244, is a potent, orally active and sel
1198078-60-2 | NT219
(Catalog# : 25067)
NT219 is a novel inhibitor of the insulin/igf signaling cascade (iis), mediating a lo
858128-57-1 | SPB linker
(Catalog# : 25066)
SPB is a agent-linker conjugate for ADC with potent anti-inflammatory activity by usi
1404380-58-0 | JTE-151
(Catalog# : 20594)
JTE-151 是一种 RORγ 抑制剂,可通过抑制与 Th17 细胞活化相关的 ROR
112108-01-7 | Ecopipam ( SCH 39166 )
(Catalog# : 25065)
Ecopipam (SCH 39166) 是一种有效的、选择性、具有口服活性的多巴胺