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Cytoskeletal Signaling
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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
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Cas号索引 8
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Cas号索引 8
854107-55-4 | Ponesimod
(Catalog# : 17030918)
Ponesimod,也被称为ACT - 128800,是一个强有力的,而且是积极的选择
882257-11-6 | P5091 (P005091)
(Catalog# : 16122795)
P5091(P005091) is a selective and potent inhibitor of ubiquitin-specific protease 7 (
847591-62-2 | PRI-724
(Catalog# : 16122785)
PRI-724 is a potent, specific inhibitor of the canonical Wnt signaling pathway in can
866206-54-4 | PRX-08066
(Catalog# : 16071114)
PRX-08066 is a a novel 5-hydroxytryptamine receptor 2B antagonist, reduces monocrotal
866323-14-0 | PXD-101
(Catalog# : 16053002)
Belinostat (trade name Beleodaq, previously known as PXD101) is a histone deacetylase
898562-94-2 | PF-2545920
(Catalog# : 012006)
PF-2545920 is a phosphodiesterase inhibitor selective for the PDE10A subtype, which i
802539-81-7 | PHA-848125
(Catalog# : 122916)
PHA-848125 is a potent, ATP-competitive CDK inhibitor for CDK2 with IC50 of 45 nM; &g
871266-63-6 | PCI-27483
(Catalog# : 110401)
PCI-27483 is a reversible small-molecule inhibitor of activated factor VII (factor VI
82508-31-4 | PSEUDOLARIC ACID B
(Catalog# : 110223)
Pseudolaric acid B is a diterpene acid isolated from the bark of Pseudolarix kaempfer
839707-37-8 | Pluripotin(SC-1)
(Catalog# : 100502)
SC1 (Pluripotin) was identified in a cell-based chemical library screen for small mol
87691-87-0 | 3-(1-Piperazinyl)-1,2-Benzisothiazole
(Catalog# : 91408)
The related APILurasidone hydrochlorideThe related intermediates4-(1,2-Benzothiazol-3
869288-64-2 | PF-573228
(Catalog# : 52816)
PF-573228 is a potent and selective FAK inhibitor with IC50 of 4 nM for inhibiton of
873786-09-5 | PLX647
(Catalog# : 52756)
PLX647 is a highly specific dual FMS/KIT kinase inhibitor with IC50 of 28/16 nM respe
827022-32-2 | Palbociclib(PD-0332991)HCl
(Catalog# : 52011)
Palbociclib (PD-0332991) HCl is a highly selective inhibitor ofCDK4/6withIC50of 11 nM
827022-33-3 | Palbociclib (PD0332991) Isethionate
(Catalog# : 52012)
Palbociclib (PD0332991) Isethionate is a highly selective inhibitor ofCDK4/6withIC50o
875320-29-9 | Quisinostat
(Catalog# : 122821)
Quisinostat is an orally available, potent, hydroxamate, pan-HDACi with broad activit
864814-88-0 | Resminostat
(Catalog# : 20652)
Resminostat, also known as 4S-201 and RAS2410, is an orally bioavailable inhibitor of
820957-38-8 | Retosiban
(Catalog# : 192193)
Retosiban,又称GSK-221149-A;是一种口服活性强、选择性强的亚纳米(Ki
874101-00-5 | RO4987655
(Catalog# : 17011603)
RO4987655,也称为CH4987655, 是一种口服活性的小分子,靶向活性蛋白激
84088-42-6 | Roquinimex
(Catalog# : 6111413)
Roquinimex (Linomide; PNU212616; ABR212616) is a quinoline derivative immunostimulant
866081-62-1 | (R) QuinoxP(R)
(Catalog# : 16062107)
(R) QuinoxP(R)
847925-91-1 | RO4929097
(Catalog# : 123001)
RO4929097 is a secretase inhibitor with IC50 of 4 nM, inhibiting cellular processing
841290-80-0 | R406 free base
(Catalog# : 122927)
R406 is a potent inhibitor of immunoglobulin E (IgE)- and IgG-mediated activation of
850807-63-5 | RSM932A
(Catalog# : 90734)
Choline kinase α (CHKA; here designated as ChoKα) is the first enzyme in the CDP-ch
88196-70-7 | (1R)-1-(3-methoxyphenyl)ethanamine
(Catalog# : 91116)
Coming soon!
856562-88-4 | (R)-1-(o-Tolyl)ethanamine hydrochloride
(Catalog# : 90716)
Coming soon!
859027-48-8 | (R)-1-Boc-3-((Dimethylamino)methyl)pyrrolidine
(Catalog# : 83121)
Coming soon!
871038-72-1 | Raltegravir potassium sal
(Catalog# : 52612)
Raltegravir potassium salt(MK0518 potassium salt) is a potent integrase (IN) inhibito
872573-93-8 | Ro-3306
(Catalog# : 52580)
Ro-3306 is a potent and selective inhibitor of CDK1 with Ki value of 35 nM for CDK1/c
863713-78-4 | SPG-601 ( VSN-16R )
(Catalog# : 24042)
SPG-601(以前称为 VSN-16R)是一种口服大麻素受体激动剂。
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag