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抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
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技术服务
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联系我们
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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Cas号索引 8
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Cas号索引 8
877387-37-6 (free base) | GSK5182
(Catalog# : 20375)
GSK5182 is a specific inverse agonist for estrogen-related receptor γ.
881639-98-1 | G-1
(Catalog# : 206103)
G-1 is a selective agonist for GPER. It acts by blocking tubulin polymerization.
827319-43-7 | GW-870086
(Catalog# : 1811263)
GW-870086是一种糖皮质激素受体激动剂,有望用于哮喘和特应性皮炎
880635-03-0 | GW6471
(Catalog# : 181151)
GW6471是一种PPARα拮抗剂(IC50 = 0.24μM)。GW6471提高SMRT和NCoR的蛋白质亲
817194-38-0 | GSK180736A (GSK180736)
(Catalog# : 178901)
GSK180736A是一种有效的、具有选择性的IC50 0.77 M25的GRK2抑制剂,比其
844903-58-8 | GSK163090
(Catalog# : 6111015)
GSK163090 is a potent, selective, and orally active 5-HT1A/B/D receptor antagonist wi
863513-91-1 | GRT-6005
(Catalog# : 16071110)
Cebranopadol is a potent nociceptin/orphanin FQ peptide (NOP) and opioid receptor ago
873652-48-3 | GDC-0152
(Catalog# : 16071101)
GDC-0152 is a second mitochondrial activator of caspases (Smac) mimetic inhibitor of
839706-07-9 | GNF-7
(Catalog# : 16060604)
BenzaMide
870483-87-7 | GW2580
(Catalog# : 122524)
GW2580 is an orally bioavailable inhibitor of c-FMS kinase; completely inhibited huma
850664-21-0 | GSK269962A
(Catalog# : 102206)
GSK269962A(CAS 850664-21-0) is a potent ROCK inhibitor (IC50 values are 1.6 and 4 nM
851983-85-2 | Galeterone
(Catalog# : 62003)
Galeterone(VN/124-1,TOK001) is a highly selective, multi-targeted, oral small molecul
864082-47-3 | GSK429286A
(Catalog# : 52629)
GSK429286A is a selective inhibitor of ROCK1 and ROCK2 with IC50 of 14 nM and 63 nM,
888216-25-9 | Ganetespib(STA-9090)
(Catalog# : 52021)
Ganetespib blocked the ability of HSP90 to bind to biotinylated geldanamycin and disr
877768-84-8 | H2-Gamendazole
(Catalog# : 24145)
H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycysti
86227-47-6 | Icosapent ethyl
(Catalog# : 24045)
Icosapent ethyl is used for the treatment of hypertriglyceridemia.
851870-24-1 | 4-iodo-2-isopropyl-1-Methyl-1H-iMidazole
(Catalog# : 2062023)
887401-93-6 | INCB3284甲磺酸盐
(Catalog# : 191143)
INCB3284是一种有效的、选择性的、可口服的hCCR2拮抗剂。
835619-41-5 | Indeglitazar
(Catalog# : 1812131)
Indeglitazar,也称为PPM-204和PLX-204,是一个可口服的过氧化物酶体增
832115-62-5 | ISX-9
(Catalog# : 17022713)
ISX-9 is a neurogenic agent. Isx-9 promotes neurogenesis in vivo, enhancing the proli
873225-46-8 | IKK-16
(Catalog# : 16123017)
IKK-16 is a potent and slective inhibitor of IB kinase (IKK) (IC50 values are 40, 70
866927-10-8 | IC87201
(Catalog# : 16122820)
IC87201 is a nNOS-PDZ/PSD-95-PDZ inhibitor. IC87201 showed great promise in cellular
851870-28-5 | 5-Iodo-2-isopropyl-1-methyl-1H-imidazole
(Catalog# : 021701)
Coming soon!
857679-55-1 | INCB8761 (PF-4136309)
(Catalog# : 92210)
INCB8761(PF-4136309) is a potent, selective, and orally bioavailable CCR2 antagonist.
879-37-8 | Indole-3-Acetamide
(Catalog# : 81920)
Coming soon!
873054-44-5 | Ivacaftor
(Catalog# : 52805)
Ivacaftor (VX-770) is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR wit
878489-28-2 | JNJ 303
(Catalog# : 122938)
Coming soon!
881202-45-5 | JNJ-26854165 (Serdemetan)
(Catalog# : 52522)
JNJ-26854165 (Serdemetan) acts as a HDM2 ubiquitin ligase antagonist and also induces
888032-58-4 | KPI-10
(Catalog# : 20277)
KPI-10 is a new compound currently being studied for its efficacy in the treatment of
845932-30-1 | KU59403
(Catalog# : 19123)
KU59403是一种有效的选择性ATM(共济失调毛细血管扩张突变)抑制剂,
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
667411-04-3 | TRPM4-IN-2
(Catalog# : 24147)
TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibi
1534-35-6 | Isolithocholic Acid
(Catalog# : 24146)
Isolithocholic acid is a bile acid that is formed via microbial metabolism of lithoch
877768-84-8 | H2-Gamendazole
(Catalog# : 24145)
H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycysti
2095432-28-1 | CPI-455 HCl
(Catalog# : 24144)
CPI-455 is a potent and selective inhibitor of KDM5 demethylases which reduces surviv
1215115-03-9 | KH-3
(Catalog# : 24143)
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC50 value
2097938-74-2 | Stafib-2
(Catalog# : 24142)
Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with
2032123-28-5 | TCRS-417
(Catalog# : 24141)
TCRS-417 (T417) is a small molecule compound capable of docking to the interface betw
1096144-06-7 | PST3 1a
(Catalog# : 24140)
PST3 1a is a Novel selective inhibitor of the N-acetylglucosamine glycosyltransferase
2225824-53-1 | YTX-465
(Catalog# : 24139)
YTX-465 is a SCD inhibitor. YTX-465 strongly reduced fatty desaturation in a concentr
944808-88-2 | CAY10566
(Catalog# : 10403)
Coming soon!