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Bromides
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Indoles and Oxindoles
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
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Deuterated
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Pyridines
Pyrimidines
Quinolines
Sulfonamides
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产品名字索引 B
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产品名字索引 B
BMS-986142
(Catalog# : 191284, Cas# :
1643368-58-4
)
BMS-986142是一种高效、选择性、可逆的BTK抑制剂。
Blu667
(Catalog# : 191282, Cas# :
2097132-94-8
)
BLU-667是一种有效的选择性 RET 抑制剂, IC50 为0.4 nM,对突变体 RET
BAY1238097
(Catalog# : 191257, Cas# :
1564268-08-1
)
BAY1238097是一种有效的选择性BET抑制剂。BAY1238097与BET蛋白BRD上乙酰
BMS-189453
(Catalog# : 191253, Cas# :
166977-43-1
)
BMS-189453也被称为BMS453,是一个强有力的和选择性RARβ受体激动剂和
BI-671800
(Catalog# : 191213, Cas# :
1093108-50-9
)
BI-671800是一种治疗哮喘患者的CRTH2拮抗剂。BI 671800与症状控制单纯
BI-3812
(Catalog# : 19124, Cas# :
2166387-64-8
)
BI-3812是BCL6 BTB/POZ区域与多个共抑制因子相互作用的有效抑制剂。
BAY 678
(Catalog# : 1812286, Cas# :
675103-36-3
)
BAY 678是一种有效且具有选择性的人类中性粒细胞弹性蛋白酶(HNE)抑
BN-82002
(Catalog# : 1812261, Cas# :
396073-89-5
)
BN-82002又称CDC25磷酸酶抑制剂I,是一种具有抗肿瘤特性的细胞渗透
BMS-509744
(Catalog# : 1811291, Cas# :
439575-02-7
)
BMS-509744是一种有效的白介素-2诱导T细胞激酶(ITK)抑制剂(IC50 = 19 nM
BMS-688521
(Catalog# : 1811281, Cas# :
893397-44-9
)
BMS-688521是白细胞功能相关抗原-1 (LFA-1)的小分子拮抗剂。它为LFA-1
BMS-986195
(Catalog# : 1811264, Cas# :
1912445-55-6
)
BMS-986195是一种有效,共价,Bruton’s酪氨酸激酶的不可逆抑制剂(B
BAY-299
(Catalog# : 1811262, Cas# :
2080306-23-4
)
BAY-299是一种有效且具有选择性的BRD1和TAF1抑制剂(IC50的值分别为
BMS-986165
(Catalog# : 1810163, Cas# :
1609392-27-9
)
BMS-986165是具有选择性、强效、变构抑制剂的酪氨酸激酶2 (Tyk2)。
Bictegravir
(Catalog# : 187181, Cas# :
1611493-60-7
)
Bictegravir,也称为GS - 9883,是一个强有力的,无助推的每日一次HIV- 1整
Basimglurant
(Catalog# : 187121, Cas# :
1034442-21-1
)
Basimglurant,又称RO 4917523和RG-7090,是一种新型的mGlu5阴性变构调制
3BDO
(Catalog# : 186232, Cas# :
890405-51-3
)
3BDO,一种丁基内酯衍生物,可以靶向FKBP1A,激活mTOR信号通路。它
BMS-986205
(Catalog# : 185314, Cas# :
1923833-60-6
)
BMS-986205是一种抗癌药物。
Birinapant
(Catalog# : 185182, Cas# :
1260251-31-7
)
Birinapant,也被称为TL32711,是一种合成的小分子,具有潜在的抗肿
Bryostatin 1
(Catalog# : 18573, Cas# :
83314-01-6
)
苔藓虫素1是一种有效的蛋白激酶C调制器,从苔藓虫体内分离出来
BMS-813160
(Catalog# : 1842812, Cas# :
1286279-29-5
)
BMS-813160是一种有效的选择性CCR2/CCR5拮抗剂,具有潜在的免疫调节
BRD7116
(Catalog# : 184282, Cas# :
329059-55-4
)
BRD7116是白血病干细胞(LSC)活性的有效选择性抑制剂(EC50 = 200 nM)。
盐酸巴多昔芬
(Catalog# : 18496, Cas# :
198480-56-7
)
Bazedoxifene,又名WAY-140424,是第三代选择性雌激素受体调节剂(SERM)
BQR695
(Catalog# : 184218, Cas# :
1513879-21-4
)
BQR695, also known as NVP-BQR695, is a potent and selective PI4K inhibitor.
BAY1143572
(Catalog# : 181242, Cas# :
1414943-88-6
)
Atuveciclib, also known as BAY1143572, is a highly selective, potent and orally avail
BAY-1436032
(Catalog# : 181181, Cas# :
1803274-65-8
)
BAY-1436032是一个强有力的,有选择性的,有效的突变异柠檬酸脱氢酶
BGB-283
(Catalog# : 17101620, Cas# :
1446090-77-2;1446090-79-4
)
BGB-283,也称为Beigene-283或Lifirafenib,是一种新的有效的和选择性的
Belizatinib
(Catalog# : 17101619, Cas# :
1357920-84-3
)
Belizatinib,也称为TSR-011,具有受体酪氨酸激酶间变性淋巴瘤激酶(
Bioymifi
(Catalog# : 1710165, Cas# :
1420071-30-2
)
Bioymifi是DR5的活性剂(Kd = 1.2 µM; IC50 = 2 µM). Bioymifi诱导凋亡的肿瘤
BLU-554
(Catalog# : 1710162, Cas# :
1707289-21-1
)
BLU-554是针对肝癌治疗的成纤维细胞生长因子受体4(FGFR4)抑制剂
BX-517
(Catalog# : 1791314, Cas# :
850717-64-5
)
BX-517,又名PDK1 inhibitor2,是强有力的和有选择性的PDK1抑制剂。
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
TRPM4-IN-2
(Catalog# : 24147, Cas# :
667411-04-3
)
TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibi
Isolithocholic Acid
(Catalog# : 24146, Cas# :
1534-35-6
)
Isolithocholic acid is a bile acid that is formed via microbial metabolism of lithoch
H2-Gamendazole
(Catalog# : 24145, Cas# :
877768-84-8
)
H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycysti
CPI-455 HCl
(Catalog# : 24144, Cas# :
2095432-28-1
)
CPI-455 is a potent and selective inhibitor of KDM5 demethylases which reduces surviv
KH-3
(Catalog# : 24143, Cas# :
1215115-03-9
)
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC50 value
Stafib-2
(Catalog# : 24142, Cas# :
2097938-74-2
)
Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with
TCRS-417
(Catalog# : 24141, Cas# :
2032123-28-5
)
TCRS-417 (T417) is a small molecule compound capable of docking to the interface betw
PST3 1a
(Catalog# : 24140, Cas# :
1096144-06-7
)
PST3 1a is a Novel selective inhibitor of the N-acetylglucosamine glycosyltransferase
YTX-465
(Catalog# : 24139, Cas# :
2225824-53-1
)
YTX-465 is a SCD inhibitor. YTX-465 strongly reduced fatty desaturation in a concentr
CAY10566
(Catalog# : 10403, Cas# :
944808-88-2
)
Coming soon!