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抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
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Angiogenesis
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Cytoskeletal Signaling
Cell Cycle
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DNA Damage
Stem Cells & Wnt
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Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
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技术服务
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订购信息
联系我们
公司简介
联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 G
GW6471
(Catalog# : 181151, Cas# :
880635-03-0
)
GW6471是一种PPARα拮抗剂(IC50 = 0.24μM)。GW6471提高SMRT和NCoR的蛋白质亲
GSK-2830371
(Catalog# : 1810292, Cas# :
1404456-53-6
)
GSK 2830371是WiP1抑制剂。它能抑制淋巴瘤和神经母细胞瘤模型中的细
GENZ-882706
(Catalog# : 1810176, Cas# :
2070864-35-4
)
GENZ-882706是一种有效的集落刺激因子-1受体(CSF-1R)抑制剂。
GDC-0575
(Catalog# : 189272, Cas# :
1196541-47-5
)
GDC-0575 (ARRY-575, RG7741)是一种有效的选择性CHK1抑制剂,IC50为1.2 nM。
GSK-626616
(Catalog# : 188241, Cas# :
1025821-33-3
)
GSK 626616是一种YAK3/DYRK3激酶抑制剂。它是一种潜在治疗化疗性贫血
GT 949
(Catalog# : 187182, Cas# :
460330-27-2
)
GT 949是一种选择EAAT2阳性变构调制器(EC50 = 0.26 nM)。提高谷氨酸的易
GSK-J4游离
(Catalog# : 187163, Cas# :
1373423-53-0
)
GSK-J4是一种可渗透的、有效的选择性组蛋白去甲基化酶。
Gefapixant
(Catalog# : 187122, Cas# :
1015787-98-0
)
Gefapixant (MK-7264) 是一个口服的、P2X3 受体活性拮抗剂,其对人同源
GLL398
(Catalog# : 185313, Cas# :
2077980-83-5
)
GLL398是口服选择性雌激素受体下调物。
Glecaprevir
(Catalog# : 185311, Cas# :
1365970-03-1
)
Glecaprevir,也称为ABT-493和A-1282576, 是一种有效治疗HCV的NS 3/4A抑制剂
GW843682X
(Catalog# : 185292, Cas# :
660868-91-7
)
GW843682X是一种选择性抑制剂,具有polo-样激酶1 (PLK1)和polo-样激酶3
GNE-7915
(Catalog# : 18595, Cas# :
1351761-44-8
)
GNE-7915是一种有效的LRRK2激酶抑制剂。
GLPG1837
(Catalog# : 1842811, Cas# :
1654725-02-6
)
GLPG-1837,又名ABBV-974,是一种新型的关于囊性纤维化跨膜电导校准
GC376钠
(Catalog# : 184175, Cas# :
1416992-39-6
)
GC376是一种3CLpro抑制剂(3C-样蛋白酶抑制剂)。
GNF-6231
(Catalog# : 18494, Cas# :
1243245-18-2
)
GNF-6231是一种有效的、具有口服活性的、选择性的Porcupine抑制剂,
GSK-3326595
(Catalog# : 184316, Cas# :
1616392-22-3
)
GSK-3326595,也被称为EPZ015938,是一种具有口服活性的、强效的、选
GIBH-130
(Catalog# : 18428, Cas# :
1252608-59-5
)
GIBH-130 is a neuroinflammation inhibitor.
GSK872
(Catalog# : 17101621, Cas# :
1346546-69-7
)
GSK872是一个受体相互作用蛋白激酶抑制剂(RIP3)。GSK872抑制TNF-α
GSK2881078
(Catalog# : 1791316, Cas# :
1539314-06-1
)
GSK-2881078是一种潜在的对癌症恶病质的治疗选择性雄激素受体调节
GJ-103钠
(Catalog# : 1791116, Cas# :
1459687-96-7
)
GJ103氯化钠是通过自动模拟通读复合物GJ072。
GJ-103 游离酸
(Catalog# : 1791115, Cas# :
1459687-89-8
)
GJ103游离酸是通过自动模拟通读复合物GJ072。化学诱导通读提前终
10074-G5
(Catalog# : 1791112, Cas# :
413611-93-5
)
10074-G5是一种c-Myc/Max互动抑制剂。10074-G5类似于10058-F4,具体抑制c
GW0742
(Catalog# : 1791110, Cas# :
317318-84-6
)
GW0742也称为GW610742和GW0742X 是PPARδ/β激动剂。GW0742诱导有丝分裂后
Givinostat HCl
(Catalog# : 17919, Cas# :
199657-29-9
)
Givinostat或gavinostat,又名ITF2357,是一个强有力的和口服活性的组蛋
阿那匹韦
(Catalog# : 1783018, Cas# :
1350462-55-3
)
阿那匹韦,也称为MK5172,是一种被批准用于治疗丙型肝炎的药物。
GNE-3511
(Catalog# : 1781006, Cas# :
1496581-76-0
)
GNE-3511是一种具有选择性的双亮氨酸激酶(DLK,MAP3K12)抑制剂,在神经
GSK2193874
(Catalog# : 178914, Cas# :
1336960-13-4
)
GSK2193874被认定为一种选择性的、口服的TRPV4阻断剂。
GW4869
(Catalog# : 178912, Cas# :
6823-69-4
)
GW4869(二氯化物水合物)是一种可渗透的、选择性的N- Smase(中性鞘磷
GSK2982772
(Catalog# : 178911, Cas# :
1622848-92-3
)
GSK2982772是一种ATP竞争性的受体- 1(激酶)抑制剂,IC50值为1 nM。它有
GSK180736A (GSK180736)
(Catalog# : 178901, Cas# :
817194-38-0
)
GSK180736A是一种有效的、具有选择性的IC50 0.77 M25的GRK2抑制剂,比其
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
TRPM4-IN-2
(Catalog# : 24147, Cas# :
667411-04-3
)
TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibi
Isolithocholic Acid
(Catalog# : 24146, Cas# :
1534-35-6
)
Isolithocholic acid is a bile acid that is formed via microbial metabolism of lithoch
H2-Gamendazole
(Catalog# : 24145, Cas# :
877768-84-8
)
H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycysti
CPI-455 HCl
(Catalog# : 24144, Cas# :
2095432-28-1
)
CPI-455 is a potent and selective inhibitor of KDM5 demethylases which reduces surviv
KH-3
(Catalog# : 24143, Cas# :
1215115-03-9
)
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC50 value
Stafib-2
(Catalog# : 24142, Cas# :
2097938-74-2
)
Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with
TCRS-417
(Catalog# : 24141, Cas# :
2032123-28-5
)
TCRS-417 (T417) is a small molecule compound capable of docking to the interface betw
PST3 1a
(Catalog# : 24140, Cas# :
1096144-06-7
)
PST3 1a is a Novel selective inhibitor of the N-acetylglucosamine glycosyltransferase
YTX-465
(Catalog# : 24139, Cas# :
2225824-53-1
)
YTX-465 is a SCD inhibitor. YTX-465 strongly reduced fatty desaturation in a concentr
CAY10566
(Catalog# : 10403, Cas# :
944808-88-2
)
Coming soon!