武汉永璨生物科技有限公司
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抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
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others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
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Indoles and Oxindoles
Iodos
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联系我们
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 G
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产品名字索引 G
GSK-1070916
(Catalog# : 111011, Cas# :
942918-07-2
)
GSK1070916 is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3
GSK269962A
(Catalog# : 102206, Cas# :
850664-21-0
)
GSK269962A(CAS 850664-21-0) is a potent ROCK inhibitor (IC50 values are 1.6 and 4 nM
Gandotinib(LY2784544)
(Catalog# : 91415, Cas# :
1229236-86-5
)
Gandotinib is an orally bioavailable imidazopyridazine and inhibitor of Janus kinase
GW 627368
(Catalog# : 91003, Cas# :
439288-66-1
)
GW 627368X is a potent and selective competitive antagonist of the EP4 receptor with
GDC-0810 ( Brilanestrant , ARN-810 )
(Catalog# : 90731, Cas# :
1365888-06-7
)
GDC-0810 (Brilanestrant, ARN-810, RG6046) is a selective estrogen receptor degrader (
G007-LK
(Catalog# : 62908, Cas# :
1380672-07-0
)
G007-LK is specific tankyrase 1/2 inhibitor.G007-LK (66) displayed high selectivity t
GDC-0349
(Catalog# : 62702, Cas# :
1207360-89-1
)
GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR.
Galeterone
(Catalog# : 62003, Cas# :
851983-85-2
)
Galeterone(VN/124-1,TOK001) is a highly selective, multi-targeted, oral small molecul
Gimeracil
(Catalog# : 52804, Cas# :
103766-25-2
)
Gimeracil(Gimestat) is an inhibitor of dihydropyrimidine dehydrogenase (DPYD), which
GSK 525762A
(Catalog# : 52745, Cas# :
1260907-17-2
)
GSK 525762A (I-BET 762) is an inhibitor for BET proteins with IC50 of ~35 nM.
GSK429286A
(Catalog# : 52629, Cas# :
864082-47-3
)
GSK429286A is a selective inhibitor of ROCK1 and ROCK2 with IC50 of 14 nM and 63 nM,
GSK1059615
(Catalog# : 52628, Cas# :
958852-01-2
)
GSK1059615 is a dual inhibitor of PI3K/// (reversible) and mTOR with IC50 of 0.4 nM/0
GKT137831
(Catalog# : 52627, Cas# :
1218942-37-0
)
GKT137831 is a novel and specific dual Nox1/Nox4 inhibitor with Ki of 14040 nM and 11
GSK2636771
(Catalog# : 52618, Cas# :
1372540-25-4
)
GSK2636771 is a potent, orally bioavailable and selective inhibitor of PI3K (0.89 nM)
GS-7340
(Catalog# : 52611, Cas# :
379270-37-8
)
GS-7340(Tenofovir alafenamide) is a prodrug of tenofovir (TFV) that more efficiently
GSK2110183
(Catalog# : 52584, Cas# :
1047634-63-8
)
GSK2110183 is an orally bioavailable, selective, ATP-competitive and potent pan-Akt i
GW788388
(Catalog# : 52305, Cas# :
452342-67-5
)
GW788388 is a potent and selective inhibitor of ALK5 with IC50 of 18 nM, also inhibit
GNF-5
(Catalog# : 52216, Cas# :
778277-15-9
)
GNF-5, an analogue of GNF-2 with improved pharmacokinetic properties, is a selective
GNF-2
(Catalog# : 52301, Cas# :
778270-11-4
)
GNF-2 is a highly selective non-ATP competitive inhibitor of oncogenic Bcr-Abl activi
GS967
(Catalog# : 52216, Cas# :
1262618-39-2
)
GS967 is a novel, potent, and selective inhibitor of cardiac late sodium current(late
GBR 12935 dihydrochloride
(Catalog# : 52404, Cas# :
67469-81-2
)
GBR 12935 2Hcl is a potent, and selective dopamine reuptake inhibitor.
GSK126
(Catalog# : 52208, Cas# :
1346574-57-9
)
GSK126 is a potent, highly selectiveEZH2 methyltransferaseinhibitor withIC50of 9.9 nM
GSK503
(Catalog# : 51805, Cas# :
1346572-63-1
)
GSK-503 is a potent EZH2 inhibitor with potential anticancer activity. Reference: 1.
GW9662
(Catalog# : 52304, Cas# :
22978-25-2
)
GW9662 is a selective PPAR antagonist forPPARwithIC50of 3.3 nM, with at least 100 to
GNE-317
(Catalog# : 52215, Cas# :
1394076-92-6
)
GNE-317 is a potent, brain-penetrantPI3Kinhibitor
Genz-123346
(Catalog# : S1419, Cas# :
491833-30-8
)
Genz-123346 free base is an inhibitor of GL1 synthase that blocks the conversion of c
Galunisertib(LY2157299)
(Catalog# : 52017, Cas# :
700874-72-2
)
Galunisertib (LY2157299)isselective TGF- receptor kinase inhibitor. Galunisertib was
GSK3787
(Catalog# : 52018, Cas# :
188591-46-0
)
GSK3787 is as a selective and irreversible antagonist ofPPARwithpIC50of 6.6, with no
GSK 2656157
(Catalog# : 52019, Cas# :
1337532-29-2
)
GSK2656157 is an ATP-competitive and highly selective inhibitor ofPERKwithIC50of 0.9
Golvatinib (E7050)
(Catalog# : 52020, Cas# :
928037-13-2
)
Golvatinib (E7050) is a dualc-MetandVEGFR-2inhibitor with IC50 of 14 nM and 16 nM, do
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag