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抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
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Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
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Amines
Amino Acids
Anilines
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Bromides
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Deuterated
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Indoles and Oxindoles
Iodos
Nitro Compounds
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Peg Linkers
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 G
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产品名字索引 G
GSK2269557
(Catalog# : 2017883, Cas# :
1254036-77-5
)
GSK2269557,也称为GSK-2269557, 是一种有效且选择性的PI3K抑制剂.。
GDC-0326
(Catalog# : 2017881, Cas# :
1282514-88-8
)
GDC-0326是一种有效且选择性的磷酸肌醇的α-同种型3-激酶抑制剂(PI
GSK-1521498
(Catalog# : 20178215, Cas# :
1007573-18-3
)
GSK-1521498是一种新型阿片受体拮抗剂。它已经被证明可以减弱奖励
GSK321
(Catalog# : 2017821, Cas# :
1816331-63-1
)
GSK321是一种有效的、选择性的IDH1突变抑制剂。GSK321对HT- 1080细胞内
GNE-272
(Catalog# : 20178121, Cas# :
1936428-93-1
)
GNE-272对CBP / EP300的溴域具有很强的选择性(CBP IC50 = 0.02 μM, EP300 IC5
胍氯酚
(Catalog# : 17030702, Cas# :
5001-32-1
)
胍氯酚是一种抗高血压的药物。
GRA Ex-25
(Catalog# : 17030701, Cas# :
307983-31-9
)
GRA Ex-25是胰高血糖素受体的抑制剂。
GTS-21
(Catalog# : 16123016, Cas# :
156223-05-1
)
GTS-21, also known as DMBX-A, is a derivative of the natural product anabaseine that
GSK6853 (GSK-6853)
(Catalog# : 16123015, Cas# :
1910124-24-1
)
GSK6853 is a potent (300 pM), soluble, cell active (20 nM), and highly selective inhi
GSK583
(Catalog# : 16123014, Cas# :
1346547-00-9
)
GSK583 is a Highly Potent and Selective Inhibitor of RIP2 Kinase (RIP2K bing IC50=5 n
GSK369796 Dihydrochloride
(Catalog# : 16123013, Cas# :
1010411-21-8
)
GSK369796, also known as N-tert-butylisoquine, is an anti-malaria drug candidate. GSK
GSK2801
(Catalog# : 16123012, Cas# :
1619994-68-1
)
GSK2801 is a A Selective Chemical Probe for BAZ2B/A bromodomains. BAZ2A/B belong to a
GSK-2256098
(Catalog# : 16123011, Cas# :
1224887-10-8
)
GSK2256098, also known as GTPL7939, is a focal adhesion kinase-1 (FAK) inhibitor with
GSK137647A
(Catalog# : 16123010, Cas# :
349085-82-1
)
GSK137647A is an agonist of the free fatty acid receptor 4 (FFA4/GPR120) with pEC50s
GSK0660
(Catalog# : 16123009, Cas# :
1014691-61-2
)
GSK0660 is a selective PPAR antagonist. GSK0660 differentially regulated 273 transcri
Go6983
(Catalog# : 16123008, Cas# :
133053-19-7
)
GO6983 is a potent protein kinase C (PKC) inhibitor. GO6893 displays cardioprotective
GNE-617
(Catalog# : 16123007, Cas# :
1362154-70-8
)
GNE-617 is a potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitor with IC5
GlyH-101
(Catalog# : 16123006, Cas# :
328541-79-3
)
GlyH-101 is a CFTR inhibitor (cystic fibrosis transmembrane conductance regulator). G
GLPG-1690(ziritaxestat)
(Catalog# : 16123005, Cas# :
1628260-79-6
)
GLPG1690 is a selective autotaxin inhibitor discovered by Galapagos, with potential a
GDC-0853
(Catalog# : 16123004, Cas# :
1434048-34-6
)
GDC-0853 is orally available inhibitor of Bruton's tyrosine kinase (BTK) with potenti
GABOB (beta-hydroxy-GABA)
(Catalog# : 16122815, Cas# :
7013-05-0
)
GABOB, also known as -Amino--hydroxybutyric acid, -hydroxy--aminobutyric acid, -hydro
Gabexate mesylate
(Catalog# : 16122814, Cas# :
56974-61-9
)
Gabexate is a serine protease inhibitor which is used therapeutically (as gabexate me
Glasdegib (PF-04449913)
(Catalog# : 16122787, Cas# :
1095173-27-5
)
Glasdegib (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibit
Go6976
(Catalog# : 16122723, Cas# :
136194-77-9
)
Go6976 is a potent PKC inhibitor with IC50 of 7.9 nM, 2.3 nM, and 6.2 nM for PKC (Rat
GSK2292767
(Catalog# : 16122702, Cas# :
1254036-66-2
)
GSK2292767 is a potent and selective PI3K inhibitor.GSK2292767 is highly selective fo
GSK2981278
(Catalog# : 6111521, Cas# :
1474110-21-8
)
ROR modulator 1 is a retinoid-related orphan receptor gamma (RORy) modulator, extract
GSK163090
(Catalog# : 6111015, Cas# :
844903-58-8
)
GSK163090 is a potent, selective, and orally active 5-HT1A/B/D receptor antagonist wi
GSK-591
(Catalog# : 6111009, Cas# :
1616391-87-7
)
EPZ015866 (GSK591) is a potent selective inhibitor of the arginine methyltransferase
GSK2269557 free base
(Catalog# : 611826, Cas# :
1254036-71-9
)
GSK-2269557 (free base) is a potent and selective PI3Kδ inhibitor over the closely r
GSK2141795 (hydrochloride)
(Catalog# : 611807, Cas# :
1047635-80-2
)
GSK2141795 Hcl is a potent and selective pan-Akt inhibitor with IC50 values of 180 nM
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
TRPM4-IN-2
(Catalog# : 24147, Cas# :
667411-04-3
)
TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibi
Isolithocholic Acid
(Catalog# : 24146, Cas# :
1534-35-6
)
Isolithocholic acid is a bile acid that is formed via microbial metabolism of lithoch
H2-Gamendazole
(Catalog# : 24145, Cas# :
877768-84-8
)
H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycysti
CPI-455 HCl
(Catalog# : 24144, Cas# :
2095432-28-1
)
CPI-455 is a potent and selective inhibitor of KDM5 demethylases which reduces surviv
KH-3
(Catalog# : 24143, Cas# :
1215115-03-9
)
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC50 value
Stafib-2
(Catalog# : 24142, Cas# :
2097938-74-2
)
Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with
TCRS-417
(Catalog# : 24141, Cas# :
2032123-28-5
)
TCRS-417 (T417) is a small molecule compound capable of docking to the interface betw
PST3 1a
(Catalog# : 24140, Cas# :
1096144-06-7
)
PST3 1a is a Novel selective inhibitor of the N-acetylglucosamine glycosyltransferase
YTX-465
(Catalog# : 24139, Cas# :
2225824-53-1
)
YTX-465 is a SCD inhibitor. YTX-465 strongly reduced fatty desaturation in a concentr
CAY10566
(Catalog# : 10403, Cas# :
944808-88-2
)
Coming soon!