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抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
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Angiogenesis
Apoptosis
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MAPK
Cytoskeletal Signaling
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DNA Damage
Stem Cells & Wnt
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Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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others
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Amines
Amino Acids
Anilines
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Bromides
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Deuterated
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 G
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产品名字索引 G
GDC-0326
(Catalog# : 2017881, Cas# :
1282514-88-8
)
GDC-0326是一种有效且选择性的磷酸肌醇的α-同种型3-激酶抑制剂(PI
GSK-1521498
(Catalog# : 20178215, Cas# :
1007573-18-3
)
GSK-1521498是一种新型阿片受体拮抗剂。它已经被证明可以减弱奖励
GSK321
(Catalog# : 2017821, Cas# :
1816331-63-1
)
GSK321是一种有效的、选择性的IDH1突变抑制剂。GSK321对HT- 1080细胞内
GNE-272
(Catalog# : 20178121, Cas# :
1936428-93-1
)
GNE-272对CBP / EP300的溴域具有很强的选择性(CBP IC50 = 0.02 μM, EP300 IC5
胍氯酚
(Catalog# : 17030702, Cas# :
5001-32-1
)
胍氯酚是一种抗高血压的药物。
GRA Ex-25
(Catalog# : 17030701, Cas# :
307983-31-9
)
GRA Ex-25是胰高血糖素受体的抑制剂。
GTS-21
(Catalog# : 16123016, Cas# :
156223-05-1
)
GTS-21, also known as DMBX-A, is a derivative of the natural product anabaseine that
GSK6853 (GSK-6853)
(Catalog# : 16123015, Cas# :
1910124-24-1
)
GSK6853 is a potent (300 pM), soluble, cell active (20 nM), and highly selective inhi
GSK583
(Catalog# : 16123014, Cas# :
1346547-00-9
)
GSK583 is a Highly Potent and Selective Inhibitor of RIP2 Kinase (RIP2K bing IC50=5 n
GSK369796 Dihydrochloride
(Catalog# : 16123013, Cas# :
1010411-21-8
)
GSK369796, also known as N-tert-butylisoquine, is an anti-malaria drug candidate. GSK
GSK2801
(Catalog# : 16123012, Cas# :
1619994-68-1
)
GSK2801 is a A Selective Chemical Probe for BAZ2B/A bromodomains. BAZ2A/B belong to a
GSK-2256098
(Catalog# : 16123011, Cas# :
1224887-10-8
)
GSK2256098, also known as GTPL7939, is a focal adhesion kinase-1 (FAK) inhibitor with
GSK137647A
(Catalog# : 16123010, Cas# :
349085-82-1
)
GSK137647A is an agonist of the free fatty acid receptor 4 (FFA4/GPR120) with pEC50s
GSK0660
(Catalog# : 16123009, Cas# :
1014691-61-2
)
GSK0660 is a selective PPAR antagonist. GSK0660 differentially regulated 273 transcri
Go6983
(Catalog# : 16123008, Cas# :
133053-19-7
)
GO6983 is a potent protein kinase C (PKC) inhibitor. GO6893 displays cardioprotective
GNE-617
(Catalog# : 16123007, Cas# :
1362154-70-8
)
GNE-617 is a potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitor with IC5
GlyH-101
(Catalog# : 16123006, Cas# :
328541-79-3
)
GlyH-101 is a CFTR inhibitor (cystic fibrosis transmembrane conductance regulator). G
GLPG-1690(ziritaxestat)
(Catalog# : 16123005, Cas# :
1628260-79-6
)
GLPG1690 is a selective autotaxin inhibitor discovered by Galapagos, with potential a
GDC-0853
(Catalog# : 16123004, Cas# :
1434048-34-6
)
GDC-0853 is orally available inhibitor of Bruton's tyrosine kinase (BTK) with potenti
GABOB (beta-hydroxy-GABA)
(Catalog# : 16122815, Cas# :
7013-05-0
)
GABOB, also known as -Amino--hydroxybutyric acid, -hydroxy--aminobutyric acid, -hydro
Gabexate mesylate
(Catalog# : 16122814, Cas# :
56974-61-9
)
Gabexate is a serine protease inhibitor which is used therapeutically (as gabexate me
Glasdegib (PF-04449913)
(Catalog# : 16122787, Cas# :
1095173-27-5
)
Glasdegib (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibit
Go6976
(Catalog# : 16122723, Cas# :
136194-77-9
)
Go6976 is a potent PKC inhibitor with IC50 of 7.9 nM, 2.3 nM, and 6.2 nM for PKC (Rat
GSK2292767
(Catalog# : 16122702, Cas# :
1254036-66-2
)
GSK2292767 is a potent and selective PI3K inhibitor.GSK2292767 is highly selective fo
GSK2981278
(Catalog# : 6111521, Cas# :
1474110-21-8
)
ROR modulator 1 is a retinoid-related orphan receptor gamma (RORy) modulator, extract
GSK163090
(Catalog# : 6111015, Cas# :
844903-58-8
)
GSK163090 is a potent, selective, and orally active 5-HT1A/B/D receptor antagonist wi
GSK-591
(Catalog# : 6111009, Cas# :
1616391-87-7
)
EPZ015866 (GSK591) is a potent selective inhibitor of the arginine methyltransferase
GSK2269557 free base
(Catalog# : 611826, Cas# :
1254036-71-9
)
GSK-2269557 (free base) is a potent and selective PI3Kδ inhibitor over the closely r
GSK2141795 (hydrochloride)
(Catalog# : 611807, Cas# :
1047635-80-2
)
GSK2141795 Hcl is a potent and selective pan-Akt inhibitor with IC50 values of 180 nM
GSK-690693
(Catalog# : 161009019, Cas# :
937174-76-0
)
Pan-AKT kinase inhibitor GSK-690693 binds to and inhibits Akt kinases 1, 2, and 3, wh
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag