武汉永璨生物科技有限公司
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抑制剂/受体激动剂
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Epigenetics
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Cytoskeletal Signaling
Cell Cycle
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Stem Cells & Wnt
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Metabolism
Anti-infection
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others
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分子砌块
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Anilines
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Bromides
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Catalysts
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 L
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产品名字索引 L
LGD-4033(Ligandrol)
(Catalog# : 030907, Cas# :
1165910-22-4
)
LGD-4033, also known as VK5211 and Ligandrol, is an investigational selective androge
LY-379268
(Catalog# : 011904, Cas# :
191471-52-0
)
Coming soon!
Lefamulin acetate
(Catalog# : 011808, Cas# :
1350636-82-6
)
Coming soon!
Lefamulin
(Catalog# : 011807, Cas# :
1061337-51-6
)
Coming soon!
L-165041
(Catalog# : 011316, Cas# :
79558-09-1
)
Coming soon!
Linsitinib
(Catalog# : 010819, Cas# :
867160-71-2
)
Linsitinib is highly potent, orally efficacious and highly selective, dual ATP-compet
Lestaurtinib
(Catalog# : 010815, Cas# :
111358-88-4
)
Lesraurtinib is an orally bioavailable indolocarbazole derivative with antineoplastic
LX7101
(Catalog# : 010802, Cas# :
1192189-69-7
)
LX7101 is a potent inhibitor of LIMK1/2, ROCK2 and PKA, with IC50 of 24/1.6, 10, and
Loratadine
(Catalog# : 010435, Cas# :
79794-75-5
)
Loratadine is a selective inverse peripheral histamine H1-receptor agonist with an IC
LY2584702 free base
(Catalog# : 122909, Cas# :
1082949-67-4
)
LY2584702 is an orally available inhibitor of p70S6K signaling; inhibits p70S6K and p
LY2584702 tosylate
(Catalog# : 122907, Cas# :
1082949-68-5
)
LY-2584702 tosylate salt is an orally available inhibitor of p70S6K signaling; inhibi
L-779450
(Catalog# : 122835, Cas# :
303727-31-3
)
L-779450 is a potent, selective and ATP-competitive Raf kinase inhibitor (IC50 = 10 n
LDN193189 Hydrochloride
(Catalog# : 122830, Cas# :
1062368-62-0
)
LDN193189 Hydrochloride is a selective BMP signaling inhibitor, inhibits the transcri
LCL161
(Catalog# : 122820, Cas# :
1005342-46-0
)
LCL161 is an orally bioavailable SMAC mimetic and inhibitor of Inhibitor of Apoptosis
Lexibulin
(Catalog# : 122803, Cas# :
917111-44-5
)
Lexibulin is an orally bioavailable small-molecule with tubulin-inhibiting, vascular-
LY2228820
(Catalog# : 122509, Cas# :
862507-23-1
)
LY2228820 is a novel and potent p38MAPK inhibitor (the IC50 for p38MAPK and p38MAPK w
LY2608204
(Catalog# : 122218, Cas# :
1234703-40-2
)
LY2608204 is a activator of glucokinase (GK) with EC50 of 42 nM.
L-778123 hydrochloride
(Catalog# : 121805, Cas# :
253863-00-2
)
L-778123 hydrochloride is an inhibitor of FPTase and GGPTase-I with IC50 of 2 nM and
Laquinimod
(Catalog# : 121506, Cas# :
248281-84-7
)
Laquinimod is an experimental immunomodulator developed by Active Biotech and Teva.
LY2811376
(Catalog# : 121435, Cas# :
1194044-20-6
)
LY2811376 is a BACE1 inhibitor with marked Ab-lowering effects in animal models.
LY2886721
(Catalog# : 121427, Cas# :
1262036-50-9
)
LY2886721 is an BACE inhibitor used for the treatment of Alzheimer's Disease.
Linifanib
(Catalog# : 121416, Cas# :
796967-16-3
)
Linifanib is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR, CSF-1R, F
LY2090314
(Catalog# : 5121102, Cas# :
603288-22-8
)
LY2090314 (LY) is a glycogen synthase kinase 3 inhibitor with preclinical efficacy in
LMK 235
(Catalog# : 120422, Cas# :
1418033-25-6
)
LMK 235 is a selective histone deacetylase (HDAC) 4 and HDAC5 inhibitor, which demons
LDN-57444
(Catalog# : 110606, Cas# :
668467-91-2
)
LDN-57444 is a Uch-L1 inhibitor with Ki= 0.4 M. Ubiquitin carboxy-terminal hydrolase
Leuprolide
(Catalog# : 110603, Cas# :
53714-56-0
)
Leuprolide is an agonist at pituitary GnRH receptors.
LY2409881 trihydrochloride
(Catalog# : 101914, Cas# :
946518-60-1
)
LY2409881 trihydrochloride is a novel selective inhibitor of IKK2 with IC50 of 30 nM;
LHW090-A7
(Catalog# : 91810, Cas# :
1308256-94-1
)
Coming soon!
L189
(Catalog# : 91001, Cas# :
64232-83-3
)
L189 inhibits base excision repair (BER) and non-homologous end joining (NHEJ), which
Linagliptin
(Catalog# : 82608, Cas# :
668270-12-0
)
Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM.
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag