武汉永璨生物科技有限公司
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抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
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技术服务
定制合成
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订购信息
联系我们
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 L
Linperlisib free base
(Catalog# : 2061309, Cas# :
1702816-75-8
)
Linperlisib, also known as YY-20394 and PI3Kδ-IN-2, is a potent and selective PI3Kδ
L006235
(Catalog# : 2061307, Cas# :
294623-49-7
)
L006235 is a potent, reversible cathepsin K inhibitor (IC50 = 0.25 nM) that displays
LML-134
(Catalog# : 2051510, Cas# :
1542135-76-1
)
LML134 是一种具有口服活性,高选择性 H3R (组胺 3 受体) 反向激动剂
LUT-014
(Catalog# : 2042701, Cas# :
2274819-46-2
)
LUT-014 is a B-Raf Inhibitor. Leveraging the paradoxical effect of B-Raf Inhibitors,
LSZ102
(Catalog# : 2041502, Cas# :
2135600-76-7
)
LSZ102 is a potent ERα antagonist and degrader. LSZ102 showed ERα degradation IC50
LUN42589
(Catalog# : 204502, Cas# :
1848242-58-9
)
LUN42589,也称为PI3K / mTOR抑制剂2,是一种有效的双重pan-PI3K / mTOR抑
Lerociclib
(Catalog# : 204302, Cas# :
1628256-23-4 (free base)
)
Lerociclib,也称为G1T38,是一种口服,有效和选择性的CDK4 / 6抑制剂
Lemborexant (E-2006)
(Catalog# : 6111904, Cas# :
1369764-02-2
)
Lemborexant( E-2006, CAS 1369764-02-2)是食欲素OX 1和OX 2受体的双重拮抗
LY2794193
(Catalog# : 193262, Cas# :
2173037-97-1
)
LY2794193是一种高效选择性的mGlu3受体激动剂。
LY-3381916
(Catalog# : 193123, Cas# :
2166616-75-5
)
LY-3381916是一种强效的、选择性的、脑透性的IDO1活性抑制剂,与缺
LR-90
(Catalog# : 19364, Cas# :
245075-84-7
)
LR-90是一种晚期糖基化终产物(AGE)抑制剂,可抑制人单核细胞的炎
LCL521
(Catalog# : 19357, Cas# :
1226851-11-1
)
LCL521是一种酸性神经酰胺酶(ACDase)抑制剂。LCL521还抑制溶酶体酸鞘
Larotaxel
(Catalog# : 1922710, Cas# :
156294-36-9
)
Larotaxel是紫杉烷10-脱乙酰巴卡丁III的半合成衍生物,具有潜在的抗
Leniolisib
(Catalog# : 192271, Cas# :
1354690-24-6
)
Leniolisib,又名CDZ173,是一种有效的磷脂酰肌醇3激酶抑制剂(PI3K抑
Leuprolide Acetate
(Catalog# : 192261, Cas# :
74381-53-6
)
Leuprolide Acetate是一种合成的类似促性腺激素释放激素的非肽类似物
LOXO-292
(Catalog# : 192195, Cas# :
2222755-14-6
)
LOXO-292 (ARRY-192)是一种口服和临床开发的选择性研究药物,用于治
Lexibulin
(Catalog# : 19122, Cas# :
917111-49-0
)
Lexibulin,又称CYT997,是一种n型口服生物利用小分子,具有管蛋白
LP-211
(Catalog# : 1811302, Cas# :
1052147-86-0
)
LP-211是血清素5-HT7受体的选择性激动剂。
LXH254游离
(Catalog# : 1811213, Cas# :
1800398-38-2
)
LXH254是所有丝氨酸/苏氨酸蛋白激酶Raf家族成员的口服有效抑制剂
LY2828360
(Catalog# : 181172, Cas# :
1231220-79-3
)
LY2828360是一种新的有效的、选择性的、有效的CB2激动剂。
LP-533401盐酸盐
(Catalog# : 1810262, Cas# :
1040526-12-2
)
LP-533401 HCl是色氨酸羟化酶-1 (Tph-1)的抑制剂,Tph-1是内脏衍生血清
LP-922761
(Catalog# : 188101, Cas# :
1454808-95-7
)
LP-922761是一种强有力的和选择性AAK1抑制剂,在体外的IC50值为4.8±
LM22B-10
(Catalog# : 187165, Cas# :
342777-54-2
)
LM22B-10是TrkB和TrkC激动剂。LM22B-10表现为神经营养活性(EC50 = 200- 300
LY-3200882
(Catalog# : 186278, Cas# :
1898283-02-7
)
LY-3200882是一种口服TGFbeta抑制剂。LY3200882目标转化生长因子-beta (T
LX2761
(Catalog# : 186275, Cas# :
1610954-97-6
)
LX2761是一种局部作用的SGLT1抑制剂,体外强效,延缓体内肠道葡萄
L685458
(Catalog# : 186156, Cas# :
292632-98-5
)
L685458是一个强有力的和选择性γ分泌酶抑制剂。
Lometrexol disodium
(Catalog# : 186151, Cas# :
120408-07-3
)
Lometrexol是一种具有抗肿瘤活性的叶酸模拟抗代谢产物。
LB-100
(Catalog# : 185312, Cas# :
1632032-53-1
)
LB-100是一种蛋白磷酸酶2A(PP2A)抑制剂。
LY2881835
(Catalog# : 185252, Cas# :
1292290-38-0
)
LY2881835是一种有效的选择性GPR40激动剂,可能用于治疗2型糖尿病。
LOXO-195
(Catalog# : 185212, Cas# :
2097002-61-2
)
LOXO-195是一种有效的选择性TRK抑制剂,能够解决在接受larotrectinib
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
TRPM4-IN-2
(Catalog# : 24147, Cas# :
667411-04-3
)
TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibi
Isolithocholic Acid
(Catalog# : 24146, Cas# :
1534-35-6
)
Isolithocholic acid is a bile acid that is formed via microbial metabolism of lithoch
H2-Gamendazole
(Catalog# : 24145, Cas# :
877768-84-8
)
H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycysti
CPI-455 HCl
(Catalog# : 24144, Cas# :
2095432-28-1
)
CPI-455 is a potent and selective inhibitor of KDM5 demethylases which reduces surviv
KH-3
(Catalog# : 24143, Cas# :
1215115-03-9
)
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC50 value
Stafib-2
(Catalog# : 24142, Cas# :
2097938-74-2
)
Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with
TCRS-417
(Catalog# : 24141, Cas# :
2032123-28-5
)
TCRS-417 (T417) is a small molecule compound capable of docking to the interface betw
PST3 1a
(Catalog# : 24140, Cas# :
1096144-06-7
)
PST3 1a is a Novel selective inhibitor of the N-acetylglucosamine glycosyltransferase
YTX-465
(Catalog# : 24139, Cas# :
2225824-53-1
)
YTX-465 is a SCD inhibitor. YTX-465 strongly reduced fatty desaturation in a concentr
CAY10566
(Catalog# : 10403, Cas# :
944808-88-2
)
Coming soon!