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Aldehydes
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Amino Acids
Anilines
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Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
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Indoles and Oxindoles
Iodos
Nitro Compounds
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Peg Linkers
Phenols
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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On Sale
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技术服务
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联系我们
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产品名字索引 M
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产品名字索引 M
MDK-1699
(Catalog# : 184191, Cas# :
432001-69-9
)
MDK-1699,也称为Skp2抑制剂C1和SKPinC1,是一种Skp2抑制剂。
MDK-6149
(Catalog# : 184173, Cas# :
508186-14-9
)
MDK-6149,也被称为ACSS2抑制剂或Ac-CoA合成酶抑制剂I,是一种Ac-CoA合
MDK-7933
(Catalog# : 184161, Cas# :
1417997-93-3
)
MDK-7933,也称为HDAC8-IN-1,是一种HDAC8 抑制剂,在癌症细胞器的IC50
MDK7526盐酸盐
(Catalog# : 184104, Cas# :
1448189-80-7
)
MDK7526, 也称为VHL Ligand 1,Protein degrader 1是一种有效的、选择性的蛋
MRT68921
(Catalog# : 184103, Cas# :
1190379-70-4
)
MRT68921是ULK1和ULK2的抑制剂(IC50 分别为= 2.9和1.1 nM)。
MRT68921盐酸盐
(Catalog# : 184102, Cas# :
2080306-21-2
)
MRT68921是ULK1和ULK2的抑制剂(IC50分别为 = 2.9和1.1 nM)。
Mc-Val-Ala-PAB
(Catalog# : 184219, Cas# :
1870916-87-2
)
Mc-Val-Ala-PAB 是一种用于靶向药物传递的药物-药物结合剂(ADC)的有用
ML335
(Catalog# : 184216, Cas# :
825658-06-8
)
ML335 is a potent and selective TREK-1/2 Activator. ML335 is an agonist for OPRM1-OPR
ML365
(Catalog# : 184215, Cas# :
947914-18-3
)
ML365 is a potent and selective K2P3.1 TASK-1 channel blocker.
MDK7229
(Catalog# : 184211, Cas# :
111797-22-9
)
MDK7229, also known as MD2-IN-1 is a MD2 (Myeloid differentiation protein 2) inhibito
MDK6574
(Catalog# : 18421, Cas# :
2102196-57-4
)
MDK6574,也称为FAA1 agonist-1,FAA1受体激动剂。
2-甲基-7-氮杂吲哚
(Catalog# : 183131, Cas# :
23612-48-8
)
2-甲基-7-氮杂吲哚是一种医药中间体。
4-methylsulfonyl-2-(trifluoromethyl)benzaldehyde
(Catalog# : 1712293, Cas# :
1215310-75-0
)
4-methylsulfonyl-2-(trifluoromethyl)benzaldehyde isa building blocks.
MK-8617
(Catalog# : 1710163, Cas# :
1187990-87-9
)
MK-8617是一种缺氧诱导因子(HIF脯氨酰羟化酶1−3 PHD1−3),具有强效
MSC2530818
(Catalog# : 1710135, Cas# :
1883423-59-3
)
MSC2530818是一种强效、选择性,口服生物利用度与抑制剂的IC50 = 2.
MDK19922
(Catalog# : 1791512, Cas# :
132819-92-2
)
MDK19922,也称为NOD-IN-1或化合物4,是一种有效的核苷酸结合寡聚化
游离莫扎伐普坦
(Catalog# : 179154, Cas# :
137975-06-5
)
莫扎伐普坦,又名OPC 31260,是由大冢销售的血管加压素受体拮抗剂
ML-141
(Catalog# : 179152, Cas# :
71203-35-5
)
ML-141,也称为CID2950007,是Cdc42抑制剂(EC50 = 2.1μm)。
MDK30165
(Catalog# : 179138, Cas# :
2060530-16-5
)
MDK30165,也称为K-Ras(G12C)抑制剂6。
单甲基澳瑞他汀 D
(Catalog# : 20179132, Cas# :
203849-91-6
)
MMAD又称为单甲基澳瑞他汀 D,是一种高效的微管蛋白抑制剂。MMAD
ML-385
(Catalog# : 179119, Cas# :
846557-71-9
)
ML-385是强有力的和有选择性的Nrf2抑制剂(IC50 = 1.9μNrf2;M)。ML-3
ML-277
(Catalog# : 179115, Cas# :
516480-79-8
)
ML-277,又名Chk2抑制剂II,是Chk2(检查点激酶2)抑制剂。ML-277凋亡
MDK35833
(Catalog# : 179114, Cas# :
1016535-83-3
)
MDK35833又称为Oct3/4-inducer-1,是一种有效率的Oct3/4诱导者。MDK35833可
ML241 HCl
(Catalog# : 179111, Cas# :
2070015-13-1
)
ML241是强有力的和有选择性的蛋白酶抑制剂。ML241抑制P97 ATPase与IC
ML364
(Catalog# : 179833, Cas# :
1991986-30-1
)
ML364是具有潜在抗癌活性的小分子抑制剂的去泛素化酶USP2。
盐酸米托蒽醌
(Catalog# : 179827, Cas# :
70476-82-3
)
盐酸米托蒽醌是一种蒽醌抗生素,具有抗肿瘤活性的盐酸盐。米托
ML311
(Catalog# : 179826, Cas# :
315698-17-0
)
ML311,也被称为EU-5346,是强有力的和有选择性的Mcl-1和Bim蛋白相互
ML-18
(Catalog# : 179810, Cas# :
1422269-30-4
)
ML-18是蛙皮素受体亚型3(BRS-3)拮抗剂(IC50 = 4.8μm)。ML-18抑制肺
1-甲基咪唑烷-2,4,5-三酮
(Catalog# : 1781501, Cas# :
3659-97-0
)
1-甲基咪唑烷-2,4,5-三酮;1-MethyliMidazolidine-2,4,5-Trione
MK-1064
(Catalog# : 16123054, Cas# :
1207253-08-4
)
MK-1064是一种有效的、选择性和口服的Orexin OX2受体拮抗剂,用于治
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag