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抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
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MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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中间体
技术服务
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订购信息
联系我们
公司简介
联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 M
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产品名字索引 M
MDK1846
(Catalog# : 193264, Cas# :
2102501-84-6
)
MDK1846是一种强效的酮己糖激酶(KHK)抑制剂。
MMG-11
(Catalog# : 1932010, Cas# :
313254-94-3
)
MMG-11是一种高效、选择性的TLR2/1和TLR2/6信号双抑制剂,具有较低的
ML221
(Catalog# : 19311, Cas# :
877636-42-5
)
ML221是apelin (APJ)受体的拮抗剂。
Melphalan flufenamide
(Catalog# : 192279, Cas# :
380449-51-4
)
Melphalan flufenamide,也称为前药J-1,是一种将烷基化剂美法仑与氟苯
ML184
(Catalog# : 192214, Cas# :
794572-10-4
)
ML184,也称为CID2440433,是一种有效的GPR55合成受体激动剂(EC50 = 0.26µM
Mitapivat
(Catalog# : 192191, Cas# :
1260075-17-9
)
Mitapivat,又称PKM2激活剂1020,是一种治疗丙酮酸激酶缺乏症的PKM2激
MK-3903
(Catalog# : 192183, Cas# :
1219737-12-8
)
MK-3903是一种有效的选择性AMPK激活剂(EC50 = 8 nM)。
Myriocin
(Catalog# : 191283, Cas# :
35891-70-4
)
多壳球菌素,又称抗生素ISP-1和热莫西丁,是一种非典型氨基酸,
MA242 TFA
(Catalog# : 191256, Cas# :
1049704-18-8
)
MA242是MDM2和NFAT1在胰腺癌治疗中的双重抑制剂。无论p53状态如何,
MIK665
(Catalog# : 191252, Cas# :
1799631-75-6
)
MIK665,又称s64315,诱导骨髓白血病细胞分化蛋白(mcl1;Bcl2-L-3),具有
MY 5445
(Catalog# : 191211, Cas# :
78351-75-4
)
MY 5445是一种潜在的血小板聚集抑制剂。
MRS1706
(Catalog# : 19131, Cas# :
264622-53-9
)
MRS1706是一种选择性腺苷A2B受体逆激动剂,人类A2B、A1、A2A、A3受体
MRS1177
(Catalog# : 1812296, Cas# :
183721-13-3
)
MRS1177是一种生物活性化学物。
MLN-4760
(Catalog# : 1812295, Cas# :
305335-31-3
)
MLN-4760是一种血管紧张素-转换(ACE2)抑制剂。在huMNCs中,MLN-4760-B检
MDK-8384
(Catalog# : 1812254, Cas# :
761438-38-4
)
MDK-8384,也称为ALK抑制剂2,是一种有效且具有选择性的ALK抑制剂。
Mavacamten
(Catalog# : 181255, Cas# :
1642288-47-8
)
Mavacamten,又称SAR-439152和MYK-461,是一种潜在的治疗肥厚性心肌病的
MK-2048
(Catalog# : 181251, Cas# :
869901-69-9
)
MK-2048是第二代HIV-1整合酶抑制剂。
ML 351
(Catalog# : 1811282, Cas# :
847163-28-4
)
ML 351是一种选择性的12/15 LOX抑制剂,在体内具有活性。
马罗皮坦
(Catalog# : 1811261, Cas# :
147116-67-4
)
马罗皮坦,又称CJ11972,是一种神经激肽(NK1)受体拮抗剂。
MBQ-167
(Catalog# : 181152, Cas# :
2097938-73-1
)
MBQ-167是一种有效的双Rac/Cdc42抑制剂,IC50分别为103/78 nM,用于转移
MDK4882
(Catalog# : 1810301, Cas# :
94164-88-2
)
MDK4882也称为PKM2抑制剂或化学物3k,是一种 PKM2抑制剂。
MU-380
(Catalog# : 181022, Cas# :
2109805-78-7
)
MU-380是一种有效且具有选择性的CHK1抑制剂。
MRS1220
(Catalog# : 1810228, Cas# :
183721-15-5
)
MRS1220是人A3腺苷受体的一种有效且高度选择性的拮抗剂。
ME0328
(Catalog# : 1810174, Cas# :
1445251-22-8
)
ME0328是一种PARP-3的抑制剂(IC50 = 0.89 μM)。
MDK-4823
(Catalog# : 18962, Cas# :
1908414-82-3
)
MDK-4823,又称LMPTP抑制剂1;是低分子量酪氨酸磷酸酶(LMPTP)的有效抑
MDK-4774
(Catalog# : 18961, Cas# :
2036044-77-4
)
MDK-4774, 又名Porcupine-IN-1, 是一种Porcupine抑制剂。
ML-792
(Catalog# : 18941, Cas# :
1644342-14-2
)
ML-792是一种有效的选择性SAE抑制剂,在细胞检测中具有纳米极的效
ML327
(Catalog# : 187162, Cas# :
1883510-31-3
)
ML327是MYC的阻滞剂。ML327介导了E-cadherin的转录去抑制和对上皮-间充
MDK3627
(Catalog# : 187161, Cas# :
1421373-62-7
)
MDK3627,也被称为突变EGFR抑制剂,是一种选择性和强效突变的EGFR抑
MLN8054
(Catalog# : 18742, Cas# :
869363-13-3
)
MLN8054是一种MLN8054的极光激酶抑制剂,它是一种口服的生物活性药
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
TRPM4-IN-2
(Catalog# : 24147, Cas# :
667411-04-3
)
TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibi
Isolithocholic Acid
(Catalog# : 24146, Cas# :
1534-35-6
)
Isolithocholic acid is a bile acid that is formed via microbial metabolism of lithoch
H2-Gamendazole
(Catalog# : 24145, Cas# :
877768-84-8
)
H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycysti
CPI-455 HCl
(Catalog# : 24144, Cas# :
2095432-28-1
)
CPI-455 is a potent and selective inhibitor of KDM5 demethylases which reduces surviv
KH-3
(Catalog# : 24143, Cas# :
1215115-03-9
)
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC50 value
Stafib-2
(Catalog# : 24142, Cas# :
2097938-74-2
)
Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with
TCRS-417
(Catalog# : 24141, Cas# :
2032123-28-5
)
TCRS-417 (T417) is a small molecule compound capable of docking to the interface betw
PST3 1a
(Catalog# : 24140, Cas# :
1096144-06-7
)
PST3 1a is a Novel selective inhibitor of the N-acetylglucosamine glycosyltransferase
YTX-465
(Catalog# : 24139, Cas# :
2225824-53-1
)
YTX-465 is a SCD inhibitor. YTX-465 strongly reduced fatty desaturation in a concentr
CAY10566
(Catalog# : 10403, Cas# :
944808-88-2
)
Coming soon!