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Cytoskeletal Signaling
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others
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分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
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技术服务
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订购信息
联系我们
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
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订购信息
联系我们
公司简介
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产品名字索引 M
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产品名字索引 M
1-甲基咪唑烷-2,4,5-三酮
(Catalog# : 1781501, Cas# :
3659-97-0
)
1-甲基咪唑烷-2,4,5-三酮;1-MethyliMidazolidine-2,4,5-Trione
MK-1064
(Catalog# : 16123054, Cas# :
1207253-08-4
)
MK-1064是一种有效的、选择性和口服的Orexin OX2受体拮抗剂,用于治
MI-503
(Catalog# : 178908, Cas# :
1857417-13-0
)
MI-503是一种具有IC50为14.7 nM的有效和选择性的menin - mll抑制剂。在
Merestinib (LY2801653)
(Catalog# : 178905, Cas# :
1206799-15-6
)
Merestinib,又名LY2801653,是一种可口服的小分子抑制剂,原癌基因
米格鲁特盐酸盐
(Catalog# : 2017824, Cas# :
210110-90-0
)
米格鲁特, 也称为OGT 918,是Actelion开发的一种药物,主要用于治疗I
MK-0812
(Catalog# : 2017080111, Cas# :
624733-88-6
)
MK-0812是一种有效、选择性的CCR2拮抗剂。趋化因子受体2(CCR2)是单核
红曲素
(Catalog# : 201708015, Cas# :
21516-68-7
)
它是一种有效的抑制剂,是由car纤维组织形成来测量不利的化学或
美芬妥因
(Catalog# : 174161, Cas# :
50-12-4
)
美芬妥因是一个乙内酰脲,用作抗惊厥剂。美芬妥因(CAS 50-12- 4)是
MT-DADMe-ImmA
(Catalog# : 703301, Cas# :
653592-04-2
)
Methylthio-DADMe-immucillin-A (MT-DADMe-ImmA) 是一种5 -甲基硫腺苷磷酸化酶
MI-463
(Catalog# : 17031006, Cas# :
1628317-18-9
)
MI-463是一种Menin-MLL强力抑制剂,与IC50值15.3 nM相互作用。
ML-098
(Catalog# : 17030910, Cas# :
878978-76-8
)
ML-098, 也叫 CID- 7345532,是GTP结合蛋白Rab7(EC50 = 77.6 nM)的激活剂。
ML-265
(Catalog# : 17030804, Cas# :
1221186-53-3
)
ML265是一个强有力的PKM2活化剂诱导四聚体,降低肿瘤的形成和大小
MN-64
(Catalog# : 17030717, Cas# :
92831-11-3
)
MN-64 是一种有效的、选择性的Tankyrase 1和2抑制剂(IC50值分别为6和
ML241
(Catalog# : 17030714, Cas# :
1346528-06-0
)
ML241是一种p97 ATPase有效的选择性抑制剂。ML241抑制p97 ATPase的IC(50)值
ML348
(Catalog# : 17030712, Cas# :
899713-86-1
)
ML348,又称CID 3238952;SID 160654487,是一个可逆的LYPLA1抑制剂,IC50值
MMAF (Monomethyl auristatin F)
(Catalog# : 17030611, Cas# :
745017-94-1
)
一甲基澳瑞他汀 F(MMAF)是一种合成抗肿瘤药物。它是一些实验性抗
Merimepodib
(Catalog# : 17030308, Cas# :
198821-22-6
)
Merimepodib, 也称为VX-497,是有效的口服生物IMPDH抑制剂,它可以抑制
ML-264
(Catalog# : 17030302, Cas# :
1550008-55-3
)
ML-264是一种Krüppel-like因子5(KLF5)抑制剂,能有效抑制结直肠癌的生
MK-8245
(Catalog# : 17030109, Cas# :
1030612-90-8
)
MK-8245是一种有效的、以肝脏为靶点的SCD抑制剂,具有临床前抗糖
MLN-1117
(Catalog# : 17030101, Cas# :
1268454-23-4
)
Serabelisib(又名MLN1117,INK1117,TAK- 117)是一类具有潜在抗肿瘤活性的磷
ML-281
(Catalog# : 17022811, Cas# :
1404437-62-2
)
ML-281是一种有效的选择性STK33抑制剂(IC50 = 14nm)。与其他STK33抑制剂
马拉维若
(Catalog# : 17022804, Cas# :
376348-65-1
)
马拉维若(UK-427857; Selzentry; Celsentri) 是选择性CCR5拮抗剂(IC50 = 6.4 nM
单甲基奥立斯丁
(Catalog# : 17022403, Cas# :
474645-27-7
)
MMAE,又称单甲基奥立斯丁,是一种合成的抗肿瘤药物。
Monastrol
(Catalog# : 17021322, Cas# :
329689-23-8
)
Monastrol是一种细胞可渗透的小分子抑制剂,它对保持半纺锤的分离
MS049
(Catalog# : 17021313, Cas# :
1502816-23-0
)
MS049是PRMT4和PRMT6的一种有效的选择性抑制剂,IC50分别为34 nM和43 n
Miransertib(ARQ 092)
(Catalog# : 17021301, Cas# :
1313883-00-9
)
ARQ 092是一种新型的口服生物可用性和选择性AKT通路抑制剂,在晚
MT-DADMe-ImmA(MTDIA HCl)
(Catalog# : 712101, Cas# :
1399840-35-7
)
MT-DADMe-ImmA(MTDIA盐酸盐)是一种新型的MTAP抑制剂,具有治疗头颈部和
7-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine
(Catalog# : 17011908, Cas# :
7752-54-7
)
7-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine
ML-7
(Catalog# : 17011107, Cas# :
110448-33-4
)
ML-7是平滑肌肌球蛋白轻链激酶的抑制剂(MLCK),Ki值为0.3μM。
MX69
(Catalog# : 17011105, Cas# :
1005264-47-0
)
MX69是一种MDM2/XIAP抑制剂, 用于治疗癌症。
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
TRPM4-IN-2
(Catalog# : 24147, Cas# :
667411-04-3
)
TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibi
Isolithocholic Acid
(Catalog# : 24146, Cas# :
1534-35-6
)
Isolithocholic acid is a bile acid that is formed via microbial metabolism of lithoch
H2-Gamendazole
(Catalog# : 24145, Cas# :
877768-84-8
)
H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycysti
CPI-455 HCl
(Catalog# : 24144, Cas# :
2095432-28-1
)
CPI-455 is a potent and selective inhibitor of KDM5 demethylases which reduces surviv
KH-3
(Catalog# : 24143, Cas# :
1215115-03-9
)
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC50 value
Stafib-2
(Catalog# : 24142, Cas# :
2097938-74-2
)
Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with
TCRS-417
(Catalog# : 24141, Cas# :
2032123-28-5
)
TCRS-417 (T417) is a small molecule compound capable of docking to the interface betw
PST3 1a
(Catalog# : 24140, Cas# :
1096144-06-7
)
PST3 1a is a Novel selective inhibitor of the N-acetylglucosamine glycosyltransferase
YTX-465
(Catalog# : 24139, Cas# :
2225824-53-1
)
YTX-465 is a SCD inhibitor. YTX-465 strongly reduced fatty desaturation in a concentr
CAY10566
(Catalog# : 10403, Cas# :
944808-88-2
)
Coming soon!