武汉永璨生物科技有限公司
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抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 R
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产品名字索引 R
R112
(Catalog# : 031003, Cas# :
575474-82-7
)
R112 is an ATP-competitive inhibitor of Syk kinase with a Ki of 96 nM. R112 inhibits
Ro 46-2005
(Catalog# : 031001, Cas# :
150725-87-4
)
Ro 46-2005 is a novel synthetic non-peptide endothelin receptor antagonist, inhibits
RAD140
(Catalog# : 030909, Cas# :
1182367-47-0
)
Coming soon!
Robalzotan tartrate hydrate
(Catalog# : 011907, Cas# :
169758-66-1
)
Coming soon!
Radotinib
(Catalog# : 011307, Cas# :
926037-48-1
)
Radotinib is an orally available, a second-generation tyrosine kinase inhibitor of Bc
Ruxolitinib
(Catalog# : 01118, Cas# :
941678-49-5
)
Ruxolitinib is the first potent, selective, JAK1/2 inhibitor to enter the clinic with
Ro 5126766
(Catalog# : 010812, Cas# :
946128-88-7
)
Ro 5126766 is a potent and selective dual RAF/MEK inhibitor. For SK-MEL-28, SK-MEL-2,
Refametinib
(Catalog# : 010810, Cas# :
923032-37-5
)
Refametinib is an orally bioavailable selective MEK inhibitor with potential antineop
Raltegravir
(Catalog# : 010412, Cas# :
518048-05-0
)
Raltegravir is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in
Ridaforolimus
(Catalog# : 123018, Cas# :
572924-54-0
)
Ridaforolimus is a selective mTOR inhibitor with IC50 of 0.2 nM; while not classified
R428
(Catalog# : 123010, Cas# :
1037624-75-1
)
R428 is a potent and selective small-molecule inhibitor(IC50=14 nM), blocks the activ
Rucaparib
(Catalog# : 123005, Cas# :
283173-50-2
)
Rucaparib is an inhibitor of PARP with Ki of 1.4 nM for PARP1, also showing binding a
RO4929097
(Catalog# : 123001, Cas# :
847925-91-1
)
RO4929097 is a secretase inhibitor with IC50 of 4 nM, inhibiting cellular processing
R788
(Catalog# : 122928, Cas# :
901119-35-5
)
Fostamatinib is a small molecule Syk kinase inhibitor with potential anti-inflammator
R406 free base
(Catalog# : 122927, Cas# :
841290-80-0
)
R406 is a potent inhibitor of immunoglobulin E (IgE)- and IgG-mediated activation of
RGB-286638 free base
(Catalog# : 122917, Cas# :
784210-88-4
)
RGB-286638 is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/5 nM for cyclin
Ravidasvir hydrochloride
(Catalog# : 122904, Cas# :
1303533-81-4
)
Ravidasvir is a second-generation, orally active, potent and selective HCV NS5A prote
Rofecoxib
(Catalog# : 122837, Cas# :
162011-90-7
)
Rofecoxib is a synthetic, nonsteroidal derivative of phenyl-furanone with antiinflamm
Remodelin hydrobromide
(Catalog# : 122823, Cas# :
1622921-15-6
)
Remodelin HBr salt is a novel potent and selective inhibitor of the acetyl-transferas
RTA-408
(Catalog# : 122808, Cas# :
1474034-05-3
)
RTA-408 is a synthetic triterpenoid that potently activates the antioxidative transcr
Rolapitant
(Catalog# : 122804, Cas# :
552292-08-7
)
Rolapitant is a potent, highly selective, long-acting Neurokinin-1 (NK-1) receptor an
RQ 00203078
(Catalog# : 122521, Cas# :
1254205-52-1
)
RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist (IC50
RI-1
(Catalog# : 122404, Cas# :
415713-60-9
)
RI-1 is a RAD51 inhibitor with IC50 ranging from 5 to 30 M.
Rabeprazole sodium
(Catalog# : 122403, Cas# :
117976-90-6
)
Rabeprazole sodium is an antiulcer drug in the class of proton pump inhibitors.
RAF265
(Catalog# : 122202, Cas# :
927880-90-8
)
RAF265 is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 n
Ramosetron(Hydrochloride)
(Catalog# : 5121408, Cas# :
132907-72-3
)
Ramosetron (INN) is a serotonin 5-HT3 receptor antagonist for the treatment of nausea
Roflumilast
(Catalog# : 121419, Cas# :
162401-32-3
)
Roflumilast is a drug which acts as a selective, long-acting inhibitor of the enzyme
Rilpivirine
(Catalog# : 111904, Cas# :
500287-72-9
)
Rilpivirine is a pharmaceutical drug, developed by Tibotec, for the treatment of HIV
RGFP966
(Catalog# : 111005, Cas# :
1396841-57-8
)
RGFP966 is a potent and selective histone deacetylase 3 (HDAC3) inhibitor (IC₅₀ =
Rimonabant
(Catalog# : 110222, Cas# :
168273-06-1
)
Rimonabant is a selective central cannabinoid (CB1) receptor inverse agonist with Ki
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
TRPM4-IN-2
(Catalog# : 24147, Cas# :
667411-04-3
)
TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibi
Isolithocholic Acid
(Catalog# : 24146, Cas# :
1534-35-6
)
Isolithocholic acid is a bile acid that is formed via microbial metabolism of lithoch
H2-Gamendazole
(Catalog# : 24145, Cas# :
877768-84-8
)
H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycysti
CPI-455 HCl
(Catalog# : 24144, Cas# :
2095432-28-1
)
CPI-455 is a potent and selective inhibitor of KDM5 demethylases which reduces surviv
KH-3
(Catalog# : 24143, Cas# :
1215115-03-9
)
KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC50 value
Stafib-2
(Catalog# : 24142, Cas# :
2097938-74-2
)
Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with
TCRS-417
(Catalog# : 24141, Cas# :
2032123-28-5
)
TCRS-417 (T417) is a small molecule compound capable of docking to the interface betw
PST3 1a
(Catalog# : 24140, Cas# :
1096144-06-7
)
PST3 1a is a Novel selective inhibitor of the N-acetylglucosamine glycosyltransferase
YTX-465
(Catalog# : 24139, Cas# :
2225824-53-1
)
YTX-465 is a SCD inhibitor. YTX-465 strongly reduced fatty desaturation in a concentr
CAY10566
(Catalog# : 10403, Cas# :
944808-88-2
)
Coming soon!