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抑制剂/受体激动剂
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Epigenetics
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Angiogenesis
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Cytoskeletal Signaling
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Neuronal Signaling
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Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
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others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
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Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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On Sale
中间体
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定制合成
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订购信息
联系我们
公司简介
联系我们
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产品名字索引 S
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产品名字索引 S
Selinexor free base
(Catalog# : 2051501, Cas# :
1393477-72-9 (free base)
)
Selinexor, also known as KPT-330, is an orally bioavailable, potent and selective XPO
Simurosertib
(Catalog# : 2041504, Cas# :
1330782-76-7
)
Simurosertib, also known as TAK-931, is an orally bioavailable inhibitor of cell divi
SGC2085 free base
(Catalog# : 204609, Cas# :
1821908-48-8 (free base)
)
SGC2085 is a Potent and Selective Coactivator Associated Arginine Methyltransferase 1
Segetalin B
(Catalog# : 204501, Cas# :
164991-89-3
)
Segetalin B is natural product isolated from Seeds of Vaccaria Segetalis. Segetalin B
S26131
(Catalog# : 112592, Cas# :
296280-56-3
)
S26131 is a bioactive chemical.
SI-113
(Catalog# : 111896, Cas# :
1392816-46-4
)
SI113 is a specific inhibitor of the Sgk1 kinase activity, counteracting cancer cell
IPI145中间体
(Catalog# : 196301, Cas# :
1350643-72-9
)
Selisistat ( EX-527 )
(Catalog# : 52001, Cas# :
49843-98-3
)
Selisistat 是第一个确定的有效且可渗透细胞的 SIRT1 特异性抑制剂,
ST-193
(Catalog# : 193261, Cas# :
489416-12-8
)
ST-193是一种有效的广谱沙粒病毒抑制剂。抑制Guanarito、Junin、Lassa
SPL-707
(Catalog# : 193209, Cas# :
2195361-33-0
)
SPL-707是第一种选择性口服活性SPPL2a抑制剂。密切相关的酶γ-secret
SHP394
(Catalog# : 193122, Cas# :
2055757-40-7
)
SHP394是一种有效的口服SHP2抑制剂(IC50 = 23nm),具有高亲脂性、增强
SGC-GAK-1
(Catalog# : 193113, Cas# :
2226517-76-4
)
SGC-GAK-1是一种针对atp结合位点的高效选择性GAK激酶探查。
SU 5214
(Catalog# : 19314, Cas# :
186611-04-1
)
SU 5214是酪氨酸激酶信号转导的调制器。
Silvestrol
(Catalog# : 192278, Cas# :
697235-38-4
)
Silvestrol,一种黄酮类化合物家族的成员,在体外和体内,从属的
Selpercatinib
(Catalog# : 192276, Cas# :
2152628-33-4
)
Selpercatinib是一种具有抗肿瘤作用的酪氨酸激酶抑制剂。
SM16
(Catalog# : 192215, Cas# :
614749-78-9
)
SM16是一种新型类型I的TGF-β信号传导抑制剂。
SB-674042
(Catalog# : 192151, Cas# :
483313-22-0
)
SB-674042是一种有效的选择性OX1R拮抗剂。SB-674042与OX1R高亲和力结合
Seclidemstat
(Catalog# : 192147, Cas# :
1423715-37-0
)
Seclidemstat是一种抗肿瘤药物候选药物。
Setafrastat
(Catalog# : 192146, Cas# :
1399715-48-0
)
Setafrastat是一种转胺酶抑制剂和血管内皮生长因子(VEGF)促进剂。
Saridegib
(Catalog# : 1812251, Cas# :
1037210-93-7
)
Saridegib,又称IPI-926,是一种口服生物利用的环帕胺衍生物,是Hed
SAR260301
(Catalog# : 1812134, Cas# :
1260612-13-2
)
SAR260301是强有力的和选择性组 I 磷脂酰肌醇-3-激酶(PI3K)β特定抑制
Sparsentan
(Catalog# : 1812132, Cas# :
254740-64-2
)
Sparsentan, 也称为RE-021, PS433540和DARA-a,是一种日常血管紧张素II和内
SR-0987
(Catalog# : 1810263, Cas# :
303126-97-8
)
SR-0987是一个T细胞-特异性RORγ(RORγt)受体激动剂。SR-0987诱导IL-17的
SGC-CBP30
(Catalog# : 1810244, Cas# :
1613695-14-9
)
SGC-CBP30是CREBBP (CBP)和EP300的有效选择性抑制剂;它们是一般的转录共
ST2825
(Catalog# : 1810243, Cas# :
894787-30-5
)
ST-2825是MyD88抑制剂。ST2825在小鼠实验性外伤性脑损伤后提供神经保
Seletalisib
(Catalog# : 1810221, Cas# :
1362850-20-1
)
Seletalisib,也被称为UCB-5857,是一种有效的选择性PI3激酶抑制剂,
Simenepag
(Catalog# : 1810172, Cas# :
910562-15-1
)
Simenepag,又名AGN-210676,是一种用于治疗青光眼和高眼压的小分子
SR-17018
(Catalog# : 187166, Cas# :
2134602-45-0
)
SR17018是一种muo -opioid受体激动剂,EC50为97nm。
SB-273005
(Catalog# : 186221, Cas# :
205678-31-5
)
SB-273005是一种整合素αvβ3的抑制剂。
STF-083010
(Catalog# : 185151, Cas# :
307543-71-1
)
STF-083010,也称为IRE1抑制剂I, 是IRE1/XBP1通路的抑制剂。
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
INDEX NAME NOT YET ASSIGNED
(Catalog# : 25002, Cas# :
2891709-58-1
)
HC-5404 抑制剂
(Catalog# : 25001, Cas# :
2247396-91-2
)
HC-5404 是一种新型、高选择性、有效的PERK抑制剂。
HC-5404-FU
(Catalog# : 24112, Cas# :
3034479-99-4
)
HC-5404-FU 是一种新型、高选择性、有效的PERK抑制剂。
CMP-5 2HCl
(Catalog# : 24161, Cas# :
2309409-79-6
)
CMP-5 is a potent, specific, and selective PRMT5 inhibitor, while displays no activit
Wu-5
(Catalog# : 24160, Cas# :
2630378-05-9
)
Wu-5 is a USP10 inhibitor that can inhibit FLT3 and AMPK pathways, induce FLT3-ITD de
VU-29
(Catalog# : 24159, Cas# :
890764-36-0
)
VU 29 is a potent allosteric potentiator at the rat mGlu5 receptor (EC50 = 9 nM); bin
ML-202
(Catalog# : 24158, Cas# :
1221186-52-2
)
ML-202 is an activator of pyruvate kinase M2 (PKM2).
BTA-EG4 hydrate
(Catalog# : 24157, Cas# :
921193-28-4
)
BTA-EG4 is a catalase-amyloid interaction inhibitor, which can significantly enhance
CYD19
(Catalog# : 24156, Cas# :
2415281-52-4
)
CYD19 is a potent Snail/HDAC dual target inhibitor.