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抑制剂/受体激动剂
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Cytoskeletal Signaling
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Metabolism
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Proteases
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others
PROTAC
分子砌块
Aldehydes
Amines
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Anilines
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Bromides
Carboxes
Catalysts
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Deuterated
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Indoles and Oxindoles
Iodos
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
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订购信息
联系我们
公司简介
联系我们
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产品名字索引 U
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产品名字索引 U
UF-010
(Catalog# : 16122842, Cas# :
537672-41-6
)
UF-010 is a Class I HDAC inhibitor (IC50 values are 0.06, 0.1, 0.5 and 1.5 M for HDAC
U-93631
(Catalog# : 16122841, Cas# :
152273-12-6
)
U-93631 is a GABAA receptor antagonist. U-93631 causes rapid decay of gamma-aminobuty
UC-112
(Catalog# : 6111407, Cas# :
383392-66-3
)
UC-112 is a novel potent IAP(Inhibitor of apoptosis) inhibitor; potently inhibit cell
USP7-IN-1
(Catalog# : 611931, Cas# :
1381291-36-6
)
USP7-IN-1 is a novel selective and reversible inhibitor of USP7 with IC50 of 33 uM; l
UNC0642
(Catalog# : 16071013, Cas# :
1481677-78-4
)
UNC0642 is a potent, selective inhibitor of G9a/GLP with improved PK properties. UNC0
Uprosertib (GSK2141795)
(Catalog# : 16070901, Cas# :
1047634-65-0
)
Uprosertib (GSK2141795) is a selective, ATP-competitive, and orally bioavailableAktin
UC-781
(Catalog# : 011311, Cas# :
178870-32-1
)
UC-781 is a thiocarboxanilide non-nucleoside reverse transcriptase inhibitor. It is a
UNC1215
(Catalog# : 011123, Cas# :
1415800-43-9
)
UNC1215 is a potent and selective chemical probe for the methyllysine (Kme) reading f
U-104
(Catalog# : 010440, Cas# :
178606-66-1
)
U-104 is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki of 4
UMI-77
(Catalog# : 010426, Cas# :
518303-20-3
)
UMI-77 is a novel selective Mcl-1 SMI inhibitor. UMI-77 binds to the BH3 binding groo
UNC1999
(Catalog# : 111901, Cas# :
1431612-23-5
)
UNC1999 is a potent, orally bioavailable and selective inhibitor of EZH2 and EZH1 wit
U73122
(Catalog# : 102201, Cas# :
112648-68-7
)
U73122 is a potent phospholipase C (PLC) inhibitor, which reduces agonist-induced Ca2
UNBS-5162
(Catalog# : 101907, Cas# :
956590-23-1
)
UNBS5162 is a novel naphthalimide that binds to DNA by intercalation and suppresses C
UNC0224
(Catalog# : 82404, Cas# :
1197196-48-7
)
UNC0224 is a potent and selective G9a inhibitor with IC50 of 15 nM in the G9a Thioglo
UNC0638
(Catalog# : 82403, Cas# :
1255580-76-7
)
UNC0638 is an inhibitor of G9a and GLP with excellent potency and selectivity over a
UNC-2025
(Catalog# : 72807, Cas# :
1429881-91-3
)
UNC-2025 is a novel potent and highly orally bioavailable Mer/FLT3 dual inhibitor, ca
Umeclidinium bromide
(Catalog# : 72801, Cas# :
869113-09-7
)
Umeclidinium bromide is an anticholinergic drug approved for use in combination with
UNC2250
(Catalog# : 52738, Cas# :
1493694-70-4
)
UNC2250 is a phosphorylation of endogenous Mer inhibitor with an IC50 of 9.8 nM and b
UNC0646
(Catalog# : 52710, Cas# :
1320288-17-2
)
UNC0646 is a potent and selective G9a inhibitor with IC50 of 6 nM.
UNC 0631
(Catalog# : 52709, Cas# :
1320288-19-4
)
UNC 0631 is a potent G9a inhibitor with IC50 value of 4 nM.
UNC0321
(Catalog# : 52708, Cas# :
1238673-32-9
)
UNC0321 is a potent and selective G9a inhibitor with Ki of 63 pM, UNC0321 is the firs
UNC2881
(Catalog# : 52574, Cas# :
1493764-08-1
)
UNC2881 is a potent and specific Mer kinase inhibitor; inhibits steady-state Mer kina
UNC0064-12
(Catalog# : 52214, Cas# :
1430089-64-7
)
UNC0064-12 is useful chemical agent for research use.
UNC0379
(Catalog# : 51801, Cas# :
1620401-82-2
)
UNC0379 is a selective, substrate competitive inhibitor ofN-lysine methyltransferase
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag