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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
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Neuronal Signaling
NF-κB
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
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Cas Index 4
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Cas Index 4
41100-52-1 | Memantine hydrochloride
(Catalog# : 120703)
Coming soon!
4375-15-9 | 3-methyl-2,3-dihydro-1H-indole
(Catalog# : 81943)
Coming soon!
4593-38-8 | 5-Methyl-1-indanone
(Catalog# : 81942)
Coming soon!
453562-69-1 | Motesanib
(Catalog# : 52810)
Motesanib (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of
423735-93-7 | ML161
(Catalog# : 52554)
ML-161 is an allosteric inhibitor ofPAR1withIC50of 0.26 M.
473727-83-2 | Navarixin
(Catalog# : 185168)
Navarixin, also known as SCH527123, PS291822 and MK-7123, is a potent CXCR2 antagonis
448895-37-2 | NS-1643
(Catalog# : 17030715)
NS-1643 is a Human ether-a-go-go related gene (hERG) KV11.1 channel activator (EC50 =
4008-48-4 | Nitroxoline
(Catalog# : 16122719)
Nitroxoline is a urinary antibacterial agent active against susceptible gram-positive
448232-80-1 | Naquotinib
(Catalog# : 16071107)
Naquotinib, also known as ASP8273, is an orally available, irreversible, third-genera
4311-88-0 | Necrostatin-1
(Catalog# : 52230)
Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF--induced necroptosis with
412008-21-0 | O4I4
(Catalog# : 20571)
O4I4 (compound 23) is a OCT4-inducing compound with metabolical stability.
480-11-5 | Oroxylin A
(Catalog# : 2071536)
Oroxylin A is a flavonoid that inhibits decreases in cell viability and increases in
426219-18-3 | Orteronel (racemic)
(Catalog# : 17030610)
Orteronel (racemic) is a mixture of S-Orteronel and R-Orteronel isomers. Orteronel, a
457081-03-7 | Pyridone 6
(Catalog# : 193204)
Pyridone 6, also known CMP 6 or JAK Inhibitor I, is a pan-Janus-activated kinase inhi
446022-33-9 | Pelitrexol
(Catalog# : 189131)
Pelitrexol is a GARFT inhibitor, and is also a water soluble antifolate with anti-pro
4960-10-5 | Perastine
(Catalog# : 187164)
Perastine is a biochemical.
404950-80-7 | Panobinostat
(Catalog# : 17022809)
Panobinostat(LBH-589) is a broad-spectrum HDAC inhibitor; low nanomolar concentration
418805-02-4 | PYR-41
(Catalog# : 16122793)
PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with
449811-01-2 | Pamapimod (R-1503, Ro4402257)
(Catalog# : 16122774)
Pamapimod (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activate
431898-65-6 | PS-1145
(Catalog# : 032501)
Coming soon!
477575-56-7 | PHA-665752
(Catalog# : 121418)
PHA-665752 is a potent, selective and ATP-competitive c-Met inhibitor with IC50 of 9
4382-63-2 | PFK-015
(Catalog# : 52824)
PFK-015 is an effective inhibitor of PFKFB3 with IC50 of 110 nM (recombinant PFKFB3)
483367-10-8 | Purmorphamine
(Catalog# : 52519)
Purmorphamine, which directly binds and activates Smoothened, blocks BODIPY-cyclopami
415713-60-9 | RI-1
(Catalog# : 122404)
RI-1 is a RAD51 inhibitor with IC50 ranging from 5 to 30 M.
449808-64-4 | R1487
(Catalog# : 102901)
R1487 is a p38 MAP kinase inhibitor.
46022-05-3 | (1R,2R)-(-)-1,2-Cyclohexanedicarboxylic Acid
(Catalog# : 91406)
The related APILurasidone hydrochlorideThe related intermediates4-(1,2-Benzothiazol-3
441074-81-3 | (1R)-1-(3,4-difluorophenyl)ethanamine,hydrochloride
(Catalog# : 91102)
Coming soon!
434307-26-3 | (R)-Cyclopropyl(phenyl)methanamine
(Catalog# : 90729)
Coming soon!
4187-38-6 | (R)-(+)-1-(4-Methylphenyl)ethylamine
(Catalog# : 90715)
Coming soon!
441717-40-4 | (R)-1-tert-Butyl 3-methyl pyrrolidine-1,3-dicarboxylate
(Catalog# : 83130)
Coming soon!
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
266359-83-5 | Reparixin
(Catalog# : 25050)
Reparixin is an inhibitor of CXCR2 function, which attenuates inflammatory responses
229005-80-5 | TAK-779
(Catalog# : 25049)
TAK-779 is a C-C chemokine receptor type 5 (CCR5) receptor antagonist potentially for
1402608-02-9 | BAY-1125976
(Catalog# : 25048)
BAY-1125976 is a potent and selective allosteric AKT1/2 inhibitor. BAY-1125976 exhibi
1628606-05-2 | Vimseltinib free base
(Catalog# : 25047)
Vimseltinib, also known as DCC-3014, is a potent and orally active inhibitor of the t
2128698-24-6 | 2-Propynamide, 3-[(3Z)-3-[[[4-[(dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-2-oxo-1H-indol-6-yl]-N-ethyl-
(Catalog# : 25046)
1371587-51-7 | Cavosonstat
(Catalog# : 25045)
Cavosonstat, alos known as N91115) an orally bioavailable inhibitor of S-nitrosogluta
259657-09-5 | Ivospemin Hydrochloride
(Catalog# : 25044)
Ivospemin is an antineoplastic spermine analogue.
2805997-46-8 | Survodutide
(Catalog# : 25043)
2595308-10-2 | XRD-0394
(Catalog# : 25042)
XRD-0394 is a DNA-PKcs inhibitor. XRD-0394 selectively targets, binds to and inhibits
1621999-82-3 | CC-90003
(Catalog# : 25041)
CC-90003 is an orally available inhibitor of extracellular signal-regulated kinase (E