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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
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Angiogenesis
Apoptosis
Autophagy
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MAPK
Cytoskeletal Signaling
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
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Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
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Chiral Compounds
Deuterated
Fluorides
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Iodos
Nitro Compounds
Oxazoles
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Piperidines
Pyridines
Pyrimidines
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Cas Index 4
473733-16-3 | (R)-1-(3,5-Difluorophenyl)propan-1-amine hydrochloride
(Catalog# : 81019)
Coming soon!
48208-26-0 | RG108
(Catalog# : 52501)
RG108 is a non-nucleoside inhibitor of DNA methyltransferase with IC50 of 115 nM.
459868-92-9 | Rucaparib(AG-014699,PF-01367338)
(Catalog# : 52009)
Rucaparib (AG-014699, PF-01367338) is an inhibitor ofPARPwithKiof 1.4 nM for PARP1, a
431979-47-4 | SJ-172550
(Catalog# : L20353)
SJ-172550, also known as MDMX Inhibitor II, is an inhibitor of MDMX that disrupts MDM
472981-92-3 | SB-366791
(Catalog# : 21230)
SB-366791 is a potent and selective TRPV1 antagonist. SB-366791 inhibits glutamatergi
497223-38-8 | (S)-4-(((1-Propyl-1H-imidazol-5-yl)methyl)sulfinyl)aniline
(Catalog# : 2062002)
425613-09-8 | SJ000291942
(Catalog# : 2051514)
SJ000291942 is a bone morphogenic protein (BMP) signaling activator.
49843-98-3 | Selisistat ( EX-527 )
(Catalog# : 52001)
Selisistatwas the first identified potent and cell permeable SIRT1-specific inhibitor
489416-12-8 | ST-193
(Catalog# : 193261)
ST-193 is a potent broad-spectrum arenavirus inhibitor; inhibits Guanarito, Junin, La
483313-22-0 | SB-674042
(Catalog# : 192151)
SB-674042 is potent and selective OX1R antagonist. SB-674042 binds with high affinity
447410-57-3 | SB756050
(Catalog# : 20178811)
SB-756050 is a G protein-coupled bile acid receptor 1 (GPBAR1) agonist potentially fo
425386-60-3 | Semagacestat
(Catalog# : 17022802)
Semagacestat (LY450139) is a -secretase blocker for A42, A40 and A38 with IC50 of 10.
482333-74-4 | Saccharin 1-methylimidazole (SMI)
(Catalog# : 16122716)
SMI is considered a general-purpose activator for DNA and RNA synthesis.
425637-18-9 | Sotrastaurin
(Catalog# : 16071004)
Sotrastaurin, also known as AEB-071, is an orally available pan-protein kinase C (PKC
401900-40-1 | S-4
(Catalog# : 030903)
Coming soon!
475086-01-2 | Selexipag
(Catalog# : 020105)
Selexipag is a a first-in-class orally available selective non-prostanoid IP receptor
464930-42-5 | SSR240612
(Catalog# : 011915)
Coming soon!
437742-34-2 | Salinosporamide A
(Catalog# : 111304)
Salinosporamide A is a novel marine derived proteasome inhibitor which inhibits CT-L,
405554-55-4 | SB-590885
(Catalog# : 101208)
SB590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, 11-fold greater selectivity
489415-96-5 | SBC-115076
(Catalog# : 101002)
SBC-115076 is an anti-proprotein convertase subtilisin kexin type 9 (anti-PCSK9) comp
4187-56-8 | (S)-1-(4-Chlorophenyl)ethylamine
(Catalog# : 91125)
Coming soon!
4187-33-1 | (1S)-1-(2,5-dimethylphenyl)ethanamine
(Catalog# : 91107)
Coming soon!
459147-39-8 | SW033291
(Catalog# : 81945)
SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostagl
438190-29-5 | SMI-4a
(Catalog# : 52537)
SMI-4a is a selective ATP-competitive Pim-1 kinase inhibitor with an IC50 of 21 nM fo
40592-88-9 | TLR4-C34
(Catalog# : 2061501)
TLR4-C34 is a TLR4 inhibitor that inhibits TLR4 signaling in enterocytes and macropha
444932-31-4 | TC-O9311
(Catalog# : 179828)
TC-O9311 is a potent GPR139 agonist (EC50 = 39 nM in CHO-K1 cells expressing human GP
402957-28-2 | Telaprevir
(Catalog# : 121423)
Telaprevir is a potent, selective, peptidomimetic inhibitor of the hepatitis C virus
454713-13-4 | tert-butyl N-[(3R)-1-benzylpiperidin-3-yl]carbamate
(Catalog# : 83118)
Coming soon!
475272-55-0 | Tert-butyl (3S)-3-benzylpiperazine-1-carboxylate
(Catalog# : 81904)
Coming soon!
442908-10-3 | Vipadenant
(Catalog# : 010436)
Vipadenant is an adenosine A2a antagonist with Ki of 1.3 nM; less potent for A1(Ki=69
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag