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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
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Angiogenesis
Apoptosis
Autophagy
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MAPK
Cytoskeletal Signaling
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
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Cas Index 8
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Cas Index 8
850879-09-3 | Amuvatinib
(Catalog# : 123016)
Amuvatinib is a potent and multi-targeted inhibitor of c-Kit, PDGFR and Flt3 with IC5
897383-62-9 | AST-1306
(Catalog# : 122926)
AST-1306 is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and
897732-93-3 | APD597
(Catalog# : 121804)
APD597 is a potent and selective GPR119 agonist, which is potential useful for the tr
80460-73-7 | 4-Aminobenzeneboronic Acid Hydrochloride
(Catalog# : 120701)
Coming soon!
802904-66-1 | AZD1981
(Catalog# : 102604)
AZD1981 is a potent and selective CRTh2 antagonist; displaces radio-labelled PGD2 fro
896466-04-9 | AT9283
(Catalog# : 52769)
AT9283 is a small molecule a multi-targeted inhibitor with IC50s of 4, 1.2, 1.1 and a
85650-56-2 | Asenapine maleate
(Catalog# : 52767)
Asenapine maleate(Org 5222 maleate) inhibits adrenergic receptor (1, 2A, 2B, 2C) with
850649-62-6 | Alogliptin Benzoate
(Catalog# : 52741)
Alogliptin benzoate(SYR 322) is a potent, selective inhibitor of DPP-4 with IC50 of &
850140-72-6 | Afatinib
(Catalog# : 52719)
Afatinib (BIBW2992) irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R),
852808-04-9 | ABT-737
(Catalog# : 52640)
ABT-737 is a BH3 mimetic inhibitor ofBcl-xL,Bcl-2andBcl-wwithEC50of 78.7 nM, 30.3 nM
860352-01-8 | AZD-7762
(Catalog# : 52638)
AZD7762 is a potent and selective inhibitor of Chk1 with IC50 of 5 nM; equally potent
844442-38-2 | AT7519
(Catalog# : 52314)
AT7519 is a multi-CDKinhibitor for CDK1, 2, 4, 6 and 9 withIC50of 10-210 nM. It is le
89796-99-6 | Aceclofenac
(Catalog# : 51914)
Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac.
886372-53-8 | 4-Bromo-6-methylpyridine-2-carbonitrile
(Catalog# : 171653)
4-Bromo-6-methylpyridine-2-carbonitrile, CAS 886372-53-8
885280-42-2 | 6-BENZYLOXY-3,4-DIHYDRO-1H-NAPHTHALEN-2-ONE
(Catalog# : 20372)
887650-05-7 | Bafetinib
(Catalog# : 2021221)
Bafetinib, also known as INNO-406 and NS187, is an orally bioavailable 2-phenylaminop
893397-44-9 | BMS-688521
(Catalog# : 1811281)
BMS-688521 is a small molecule antagonist of leukocyte function associated antigen-1
890405-51-3 | 3BDO
(Catalog# : 186232)
3BDO, a butyrolactone derivative, could target FKBP1A and activate the mTOR signaling
83314-01-6 | Bryostatin 1
(Catalog# : 18573)
Bryostatin 1 is a potent Protein Kinase C modulator isolated from the bryozoan Bugula
850717-64-5 | BX-517
(Catalog# : 1791314)
BX-517, also known as PDK1 inhibitor2, is a potent and selective PDK1 inhibitor.
882405-89-2 | BBT-594
(Catalog# : 179133)
BBT594, also known as NVP-BBT594, is potent and selective RET and JAK2 inhibitor. NVP
863029-99-6 | Balamapimod
(Catalog# : 2017822)
Balamapimod, also known as MKI-822, is a Ras/Raf/MEK inhibitor. Balamapimod, may be p
848695-25-0 | BIIB021
(Catalog# : 16122868)
BIIB021, also known as CNF2024, is an orally active, purine-scaffold, small-molecule
890128-81-1 | BFH772
(Catalog# : 16122778)
BFH772 is a novel potent oral VEGFR2 inhibitor, targeting VEGFR2 kinase with IC50 of
883065-90-5 | BI-78D3
(Catalog# : 16122776)
BI-78D3 is a competitive JNK inhibitor with IC50 of 280nM that displays > 100 fold
861875-60-7 | BAW2881 (NVP-BAW2881)
(Catalog# : 16122733)
BAW2881 (NVP-BAW2881) is a novel vascular endothelial growth factor (VEGF) receptor t
865783-99-9 | Briciclib
(Catalog# : 611917)
Briciclib is a small molecule that suppresses cyclin D1 accumulation in cancer cells.
859853-30-8 | BMS-690514
(Catalog# : 011102)
BMS-690514 is a potent and selective inhibitor of epidermal growth factor receptor (E
859212-16-1 | Bafetinib
(Catalog# : 122947)
Bafetinib is a potent and selective dual Bcr-Abl/Lyn inhibitor with IC50 of 5.8 nM/19
856925-71-8 | (-)-Blebbistatin
(Catalog# : 122834)
(-)-Blebbistatin is a selective inhibitor of myosin II ATPase activity with IC50 of 0
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag