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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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PROTAC
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Aldehydes
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Anilines
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Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
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Pyridines
Pyrimidines
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Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
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Other Azoles
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Name Index B
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Name Index B
Blu667
(Catalog# : 191282, Cas# :
2097132-94-8
)
Blu667 is a highly potent and selective RET inhibitor with an IC50 of 0.4 nM for wild
BAY1238097
(Catalog# : 191257, Cas# :
1564268-08-1
)
BAY1238097 is a potent and selective BET inhibitor. BAY1238097 binds to the acetylate
BMS-189453
(Catalog# : 191253, Cas# :
166977-43-1
)
BMS-189453, also known as BMS453, is a potent and selective RARβ agonist and a poten
BI-671800
(Catalog# : 191213, Cas# :
1093108-50-9
)
BI-671800 is a CRTH2 antagonist that treats patients with asthma. BI 671800 is associ
BI-3812
(Catalog# : 19124, Cas# :
2166387-64-8
)
BI-3812 is a potent inhibitor of the interaction of the BTB/POZ domain of BCL6 with s
BAY 678
(Catalog# : 1812286, Cas# :
675103-36-3
)
BAY 678 is a potent and selective cell-permeable human neutrophil elastase (HNE) inhi
BN-82002
(Catalog# : 1812261, Cas# :
396073-89-5
)
BN-82002, also known as CDC25 Phosphatase Inhibitor I, is a cell-permeable ortho-hydr
BMS-509744
(Catalog# : 1811291, Cas# :
439575-02-7
)
BMS-509744 is a potent interleukin-2 inducible T cell kinase (ITK) inhibitor (IC50 =
BMS-688521
(Catalog# : 1811281, Cas# :
893397-44-9
)
BMS-688521 is a small molecule antagonist of leukocyte function associated antigen-1
BMS-986195
(Catalog# : 1811264, Cas# :
1912445-55-6
)
BMS-986195 is a potent, covalent, irreversible inhibitor of Bruton’s tyrosine kinas
BAY-299
(Catalog# : 1811262, Cas# :
2080306-23-4
)
BAY-299 is a potent and selective BRD1 and TAF1 inhibitor (IC50 values are 6 and 13 n
BMS-986165
(Catalog# : 1810163, Cas# :
1609392-27-9
)
BMS-986165 potently binds to the Tyk2 pseudokinase domain (Ki = 0.02 nM). BMS-986165
Bictegravir
(Catalog# : 187181, Cas# :
1611493-60-7
)
Bictegravir, also known as GS-9883, is a potent, unboosted, once-Daily HIV-1 Integras
Basimglurant
(Catalog# : 187121, Cas# :
1034442-21-1
)
Basimglurant, also known as RO 4917523 and RG-7090, is a novel mGlu5 negative alloste
3BDO
(Catalog# : 186232, Cas# :
890405-51-3
)
3BDO, a butyrolactone derivative, could target FKBP1A and activate the mTOR signaling
BMS-986205
(Catalog# : 185314, Cas# :
1923833-60-6
)
BMS-986205 is an anticancer drug candidate.
Birinapant
(Catalog# : 185182, Cas# :
1260251-31-7
)
Birinapant, also known as TL32711, is a synthetic small molecule and peptido mimetic
Bryostatin 1
(Catalog# : 18573, Cas# :
83314-01-6
)
Bryostatin 1 is a potent Protein Kinase C modulator isolated from the bryozoan Bugula
BMS-813160
(Catalog# : 1842812, Cas# :
1286279-29-5
)
BMS-813160 is a potent and selective CCR2/CCR5 antagonist with potential immunomodula
BRD7116
(Catalog# : 184282, Cas# :
329059-55-4
)
BRD7116 is a potent and selective Inhibitor of leukemia stem cell (LSC) activity (EC5
Bazedoxifene acetate
(Catalog# : 18496, Cas# :
198480-56-7
)
Bazedoxifene, also known as WAY-140424, is a third generation selective estrogen rece
BQR695
(Catalog# : 184218, Cas# :
1513879-21-4
)
BQR695,也被称为NVP-BQR695, 是一种有效且具有选择性的PI4K抑制剂。
BAY1143572
(Catalog# : 181242, Cas# :
1414943-88-6
)
Atuveciclib,也被称为BAY1143572,是一种具有高度选择性、有效和口服
BAY-1436032
(Catalog# : 181181, Cas# :
1803274-65-8
)
BAY-1436032 is a potent, selective and orally available inhibitor of mutant Isocitrat
BGB-283
(Catalog# : 17101620, Cas# :
1446090-77-2;1446090-79-4
)
BGB-283, also known as Beigene-283 or Lifirafenib, is a Novel potent and selective RA
Belizatinib
(Catalog# : 17101619, Cas# :
1357920-84-3
)
Belizatinib, also known as TSR-011, is an orally available inhibitor of both the rece
Bioymifi
(Catalog# : 1710165, Cas# :
1420071-30-2
)
Bioymifi is an DR5 activator (Kd = 1.2 µM; IC50 = 2 µM). Bioymifi induces apoptosis
BLU-554
(Catalog# : 1710162, Cas# :
1707289-21-1
)
BLU-554 is a fibroblast growth factor receptor 4 (FGFR4) inhibitor potentially for th
BX-517
(Catalog# : 1791314, Cas# :
850717-64-5
)
BX-517, also known as PDK1 inhibitor2, is a potent and selective PDK1 inhibitor.
BBT-594
(Catalog# : 179133, Cas# :
882405-89-2
)
BBT594, also known as NVP-BBT594, is potent and selective RET and JAK2 inhibitor. NVP
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag