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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
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Indoles and Oxindoles
Iodos
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
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Piperidines
Pyridines
Pyrimidines
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Name Index L
Lanifibranor
(Catalog# : 184177, Cas# :
927961-18-0
)
Lanifibranor, also known as IVA-337, is a peroxisome proliferator-activated receptors
LX-2343
(Catalog# : 184131, Cas# :
333745-53-2
)
LX-2343 is a neuroprotective agent for the treatment of Alzheimer's disease.
Lazertinib
(Catalog# : 512194, Cas# :
1903008-80-9
)
Description:Lazertinib is a an orally available third-generation, selective inhibi
LYN-1604
(Catalog# : 18493, Cas# :
2088939-99-3
)
LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, a
LB42708
(Catalog# : 18443, Cas# :
226929-39-1
)
LB42708 is a potent, orally active and selective nonpeptidic farnesyltransferase inhi
LLY-283
(Catalog# : 184314, Cas# :
2040291-27-6
)
LLY-283 is a potent and selective SAM-competitive chemical probe for PRMT5.
L-778123
(Catalog# : 1711249, Cas# :
183499-57-2
)
L-778,123 is an inhibitor of FPTase and GGPTase-I.
LW6
(Catalog# : 17101618, Cas# :
934593-90-5
)
LW6 decreased HIF-1alpha protein expression without affecting HIF-1beta expression.
LF3
(Catalog# : 1710164, Cas# :
664969-54-4
)
LF3 is a specific inhibitor of the classical Wnt signaling pathway by disrupting the
LTURM-34
(Catalog# : 1710138, Cas# :
1879887-96-3
)
LTURM-34 is a novel potent and selective DNA-PK inhibitor, attenuating proliferation
LY2606368 dihydrochloride
(Catalog# : 1710137, Cas# :
1234015-54-3
)
Prexasertib (LY2606368) is an ATP-competitive CHK1 inhibitor with a Ki value of 0.9 n
LDC1267
(Catalog# : 179301, Cas# :
1361030-48-9
)
LDC1267 markedly reduced murine mammary cancer and melanoma metastases dependent on N
Lavendustin C
(Catalog# : 1791119, Cas# :
125697-93-0
)
Lavendustin C, also known as HDBA and NSC 666251, is a potent inhibitor of epidermal
Lenvatinib (E7080)
(Catalog# : 52025, Cas# :
417716-92-8
)
Lenvatinib, also known as E7080, is a synthetic, orally available inhibitor of vascul
LXS-196
(Catalog# : 1781108, Cas# :
1874276-76-2
)
<span style="color:#34495E;font-family:"font-size:14px;background-color:
LDC4297(LDC044297)
(Catalog# : 178902, Cas# :
1453834-21-3
)
LDC4297,also known as LCD044297,is a potent and selective CDK7 inhibitor.
LY3214996
(Catalog# : 2017887, Cas# :
1951483-29-6
)
LY-3214996 is a potent and selective, orally available inhibitor of extracellular sig
LTX-315
(Catalog# : 20178218, Cas# :
1345407-05-7
)
LTX-315 is an amphipathic cationic peptide potentially for the treatment of melanoma,
LY 344864
(Catalog# : 20178212, Cas# :
186544-26-3
)
LY344864 is a selective 5-HT1F receptor agonist with an affinity of 6 nM (Ki) at the
LY 344864 hydrochloride
(Catalog# : 2017828, Cas# :
1217756-94-9
)
LY344864 hydrochloride is a potent and selective 5-HT1F receptor agonist. It has an E
Lys05 trihydrochloride
(Catalog# : 17030102, Cas# :
1391426-24-6
)
Lys05, or Lys01 trihydrochloride, is a potent, water soluble lysosomal autophagy inhi
Lapatinib
(Catalog# : 17022807, Cas# :
231277-92-2
)
Lapatinib(GW-572016) is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 n
Lesinurad
(Catalog# : 17022706, Cas# :
878672-00-5
)
Lesinurad(RDEA594), once-daily inhibitor of URAT1, is a transporter in the kidney tha
LY3039478 ( Crenigacestat )
(Catalog# : 17021601, Cas# :
1421438-81-4
)
LY3039478 ( Crenigacestat ), a selective NOTCH1 inhibitor, reduces intrahepatic chola
LCI699
(Catalog# : 17021314, Cas# :
928134-65-0
)
LCI699(Osilodrostat) is a potent inhibitor of 11-hydroxylase, an enzyme catalyzing t
lumateperone(Tosylate)
(Catalog# : 17012102, Cas# :
1187020-80-9
)
Lumateperone (ITI-722/ITI-007) is a novel, first-in-class dual 5HT2A receptor antagon
Lys05
(Catalog# : 16123043, Cas# :
1391426-22-4
)
Lys05 is a potent lysosomal autophagy inhibitor. Lys05 is a previously undescribed di
LY-3177833
(Catalog# : 16123042, Cas# :
1627696-51-8
)
LY-3177833 is a potent and selective inhibitor of CDC7 (Cell Division Cycle 7-related
LY3009120
(Catalog# : 16123041, Cas# :
1454682-72-4
)
LY3009120, also known as DP-4978, is potent and selective pan-RAF inhibitor with pote
LY2334737
(Catalog# : 16123040, Cas# :
892128-60-8
)
LY2334737 is an orally available valproic acid ester of gemcitabine, a broad-spectrum
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
INDEX NAME NOT YET ASSIGNED
(Catalog# : 25002, Cas# :
2891709-58-1
)
HC-5404
(Catalog# : 25001, Cas# :
2247396-91-2
)
HC-5404 is a novel, highly selective and potent PERK inhibitor.
HC-5404-FU
(Catalog# : 24112, Cas# :
3034479-99-4
)
HC-5404-FU is a novel, highly selective and potent PERK inhibitor.
CMP-5 2HCl
(Catalog# : 24161, Cas# :
2309409-79-6
)
CMP-5 is a potent, specific, and selective PRMT5 inhibitor, while displays no activit
Wu-5
(Catalog# : 24160, Cas# :
2630378-05-9
)
Wu-5 is a USP10 inhibitor that can inhibit FLT3 and AMPK pathways, induce FLT3-ITD de
VU-29
(Catalog# : 24159, Cas# :
890764-36-0
)
VU 29 is a potent allosteric potentiator at the rat mGlu5 receptor (EC50 = 9 nM); bin
ML-202
(Catalog# : 24158, Cas# :
1221186-52-2
)
ML-202 is an activator of pyruvate kinase M2 (PKM2).
BTA-EG4 hydrate
(Catalog# : 24157, Cas# :
921193-28-4
)
BTA-EG4 is a catalase-amyloid interaction inhibitor, which can significantly enhance
CYD19
(Catalog# : 24156, Cas# :
2415281-52-4
)
CYD19 is a potent Snail/HDAC dual target inhibitor.
Phylloflavan
(Catalog# : 24155, Cas# :
98570-83-3
)
Phylloflavan is an antileishmanial agent with an intracellular EC50 of 3.2 nM in RAW