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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
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Proteases
Immunology & Inflammation
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others
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Bromides
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Chiral Compounds
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Fluorides
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Indoles and Oxindoles
Iodos
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
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Other Azoles
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Name Index L
Lanifibranor
(Catalog# : 184177, Cas# :
927961-18-0
)
Lanifibranor, also known as IVA-337, is a peroxisome proliferator-activated receptors
LX-2343
(Catalog# : 184131, Cas# :
333745-53-2
)
LX-2343 is a neuroprotective agent for the treatment of Alzheimer's disease.
Lazertinib
(Catalog# : 512194, Cas# :
1903008-80-9
)
Description:Lazertinib is a an orally available third-generation, selective inhibi
LYN-1604
(Catalog# : 18493, Cas# :
2088939-99-3
)
LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, a
LB42708
(Catalog# : 18443, Cas# :
226929-39-1
)
LB42708 is a potent, orally active and selective nonpeptidic farnesyltransferase inhi
LLY-283
(Catalog# : 184314, Cas# :
2040291-27-6
)
LLY-283 is a potent and selective SAM-competitive chemical probe for PRMT5.
L-778123
(Catalog# : 1711249, Cas# :
183499-57-2
)
L-778,123 is an inhibitor of FPTase and GGPTase-I.
LW6
(Catalog# : 17101618, Cas# :
934593-90-5
)
LW6 decreased HIF-1alpha protein expression without affecting HIF-1beta expression.
LF3
(Catalog# : 1710164, Cas# :
664969-54-4
)
LF3 is a specific inhibitor of the classical Wnt signaling pathway by disrupting the
LTURM-34
(Catalog# : 1710138, Cas# :
1879887-96-3
)
LTURM-34 is a novel potent and selective DNA-PK inhibitor, attenuating proliferation
LY2606368 dihydrochloride
(Catalog# : 1710137, Cas# :
1234015-54-3
)
Prexasertib (LY2606368) is an ATP-competitive CHK1 inhibitor with a Ki value of 0.9 n
LDC1267
(Catalog# : 179301, Cas# :
1361030-48-9
)
LDC1267 markedly reduced murine mammary cancer and melanoma metastases dependent on N
Lavendustin C
(Catalog# : 1791119, Cas# :
125697-93-0
)
Lavendustin C, also known as HDBA and NSC 666251, is a potent inhibitor of epidermal
Lenvatinib (E7080)
(Catalog# : 52025, Cas# :
417716-92-8
)
Lenvatinib, also known as E7080, is a synthetic, orally available inhibitor of vascul
LXS-196
(Catalog# : 1781108, Cas# :
1874276-76-2
)
<span style="color:#34495E;font-family:"font-size:14px;background-color:
LDC4297(LDC044297)
(Catalog# : 178902, Cas# :
1453834-21-3
)
LDC4297,also known as LCD044297,is a potent and selective CDK7 inhibitor.
LY3214996
(Catalog# : 2017887, Cas# :
1951483-29-6
)
LY-3214996 is a potent and selective, orally available inhibitor of extracellular sig
LTX-315
(Catalog# : 20178218, Cas# :
1345407-05-7
)
LTX-315 is an amphipathic cationic peptide potentially for the treatment of melanoma,
LY 344864
(Catalog# : 20178212, Cas# :
186544-26-3
)
LY344864 is a selective 5-HT1F receptor agonist with an affinity of 6 nM (Ki) at the
LY 344864 hydrochloride
(Catalog# : 2017828, Cas# :
1217756-94-9
)
LY344864 hydrochloride is a potent and selective 5-HT1F receptor agonist. It has an E
Lys05 trihydrochloride
(Catalog# : 17030102, Cas# :
1391426-24-6
)
Lys05, or Lys01 trihydrochloride, is a potent, water soluble lysosomal autophagy inhi
Lapatinib
(Catalog# : 17022807, Cas# :
231277-92-2
)
Lapatinib(GW-572016) is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 n
Lesinurad
(Catalog# : 17022706, Cas# :
878672-00-5
)
Lesinurad(RDEA594), once-daily inhibitor of URAT1, is a transporter in the kidney tha
LY3039478 ( Crenigacestat )
(Catalog# : 17021601, Cas# :
1421438-81-4
)
LY3039478 ( Crenigacestat ), a selective NOTCH1 inhibitor, reduces intrahepatic chola
LCI699
(Catalog# : 17021314, Cas# :
928134-65-0
)
LCI699(Osilodrostat) is a potent inhibitor of 11-hydroxylase, an enzyme catalyzing t
lumateperone(Tosylate)
(Catalog# : 17012102, Cas# :
1187020-80-9
)
Lumateperone (ITI-722/ITI-007) is a novel, first-in-class dual 5HT2A receptor antagon
Lys05
(Catalog# : 16123043, Cas# :
1391426-22-4
)
Lys05 is a potent lysosomal autophagy inhibitor. Lys05 is a previously undescribed di
LY-3177833
(Catalog# : 16123042, Cas# :
1627696-51-8
)
LY-3177833 is a potent and selective inhibitor of CDC7 (Cell Division Cycle 7-related
LY3009120
(Catalog# : 16123041, Cas# :
1454682-72-4
)
LY3009120, also known as DP-4978, is potent and selective pan-RAF inhibitor with pote
LY2334737
(Catalog# : 16123040, Cas# :
892128-60-8
)
LY2334737 is an orally available valproic acid ester of gemcitabine, a broad-spectrum
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Reparixin
(Catalog# : 25050, Cas# :
266359-83-5
)
Reparixin is an inhibitor of CXCR2 function, which attenuates inflammatory responses
TAK-779
(Catalog# : 25049, Cas# :
229005-80-5
)
TAK-779 is a C-C chemokine receptor type 5 (CCR5) receptor antagonist potentially for
BAY-1125976
(Catalog# : 25048, Cas# :
1402608-02-9
)
BAY-1125976 is a potent and selective allosteric AKT1/2 inhibitor. BAY-1125976 exhibi
Vimseltinib free base
(Catalog# : 25047, Cas# :
1628606-05-2
)
Vimseltinib, also known as DCC-3014, is a potent and orally active inhibitor of the t
2-Propynamide, 3-[(3Z)-3-[[[4-[(dimethylamino)methyl]phenyl]amino]phenylmethylene]-2,3-dihydro-2-oxo-1H-indol-6-yl]-N-ethyl-
(Catalog# : 25046, Cas# :
2128698-24-6
)
Cavosonstat
(Catalog# : 25045, Cas# :
1371587-51-7
)
Cavosonstat, alos known as N91115) an orally bioavailable inhibitor of S-nitrosogluta
Ivospemin Hydrochloride
(Catalog# : 25044, Cas# :
259657-09-5
)
Ivospemin is an antineoplastic spermine analogue.
Survodutide
(Catalog# : 25043, Cas# :
2805997-46-8
)
XRD-0394
(Catalog# : 25042, Cas# :
2595308-10-2
)
XRD-0394 is a DNA-PKcs inhibitor. XRD-0394 selectively targets, binds to and inhibits
CC-90003
(Catalog# : 25041, Cas# :
1621999-82-3
)
CC-90003 is an orally available inhibitor of extracellular signal-regulated kinase (E