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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
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Bromides
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Antibody-drug Conjugate/ADC Related
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
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Name Index L
LY2334737
(Catalog# : 16123040, Cas# :
892128-60-8
)
LY2334737 is an orally available valproic acid ester of gemcitabine, a broad-spectrum
LY2109761
(Catalog# : 16123039, Cas# :
700874-71-1
)
LY2109761 is a novel transforming growth factor beta receptor type I and type II dual
Luliconazole
(Catalog# : 16123038, Cas# :
187164-19-8
)
Luliconazole is an azole antifungal drug. As a 1% topical cream, luliconazole is indi
Lubiprostone
(Catalog# : 16123037, Cas# :
333963-40-9
)
Lubiprostone, also known as RU-0211, is a medication used in the management of chroni
LOXO-101 (ARRY-470)
(Catalog# : 16123036, Cas# :
1223403-58-4
)
Larotrectinib, also known as ARRY-470 and LOXO-101, is an orally bioavailable, potent
Lomitapide free base
(Catalog# : 16123035, Cas# :
182431-12-5
)
Lomitapide is a MTP inhibitor. Lomitapid is a novel agent for the treatment of homozy
Lometrexol disodium
(Catalog# : 16123034, Cas# :
106400-81-1
)
Lometrexol is a folate analog antimetabolite with antineoplastic activity. As the 6R
LGK974 (WNT974)
(Catalog# : 16123033, Cas# :
1243244-14-5
)
LGK974, aslo known as is a selective and orally bioavailable Porcupine (PORCN) inhibi
Levobupivacaine free base
(Catalog# : 16123031, Cas# :
27262-47-1
)
Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is
L67
(Catalog# : 16122828, Cas# :
325970-71-6
)
L67 is a DNA Ligase Inhibitor. L67 inhibited DNA ligases I and III. L67 is a simple c
Leukadherin-1
(Catalog# : 161227107, Cas# :
344897-95-6
)
Leukadherin-1 (LA1) is a small molecule agonist that enhances CD11b/CD18-dependent ce
Ledipasvir (GS5885)
(Catalog# : 16122765, Cas# :
1256388-51-8
)
Ledipasvir (GS5885) is a HCV NS5A polymerase inhibitor, used for the treatment of hep
LLY-507
(Catalog# : 16122739, Cas# :
1793053-37-8
)
LLY-507 is a cell-active, potent, and selective inhibitor of protein-lysine Methyltra
Lirametostat ( CPI-1205 )
(Catalog# : 16122736, Cas# :
1621862-70-1
)
Lirametostat ( CPI-1205 ) is a potent, selective, and cofactor-competitive inhibitor
L755507
(Catalog# : 16122732, Cas# :
159182-43-1
)
L-755,507 is characterized as a potent and selective 3 adrenergic receptor partial ag
LY333531
(Catalog# : 16122722, Cas# :
169939-93-9
)
LY333531 is a -specific protein kinase C inhibitor. It competitively and reversibly i
Lenalidomide hydrochloride
(Catalog# : 6111410, Cas# :
1243329-97-6
)
Lenalidomide (Revlimid, CC-5013) is a TNF- secretion inhibitor with IC50 of 13 nM
Lenalidomide hemihydrate
(Catalog# : 6111409, Cas# :
847871-99-2
)
Lenalidomide (Revlimid, CC-5013) is a TNF- secretion inhibitor with IC50 of 13 nM.Len
LOXO-101
(Catalog# : 61123, Cas# :
1223405-08-0
)
LOXO-101 is an oral potent and selective ATP-competitive inhibitor of tropomyosin rec
LPA2 antagonist 1
(Catalog# : 61120, Cas# :
1017606-66-4
)
LPA2 antagonist 1 is a selective inhibitor of LPA2 activity in with IC50 17 nM in vit
Liproxstatin-1
(Catalog# : 6111018, Cas# :
950455-15-9
)
Liproxstatin-1
Lasmiditan
(Catalog# : 6111006, Cas# :
439239-90-4
)
Lasmiditan (COL-144; LY573144) is a high-affinity, highly selective 5-HT1F receptor a
Lasmiditan hydrochloride
(Catalog# : 6111005, Cas# :
613677-28-4
)
Lasmiditan (COL-144; LY573144) is a high-affinity, highly selective 5-HT1F receptor a
Litronesib
(Catalog# : 611944, Cas# :
910634-41-2
)
Litronesib is a selective, allosteric inhibitor of Eg5, which may result in mitotic d
LY 303511 hydrochloride
(Catalog# : 611819, Cas# :
2070014-90-1
)
LY303511 Hcl, an inactive analogue of LY294002, is a mTOR inhibitor that did not inhi
LY 303511
(Catalog# : 611818, Cas# :
154447-38-8
)
LY303511, an inactive analogue of LY294002, is a mTOR inhibitor that did not inhibit
LY3023414
(Catalog# : 611808, Cas# :
1386874-06-1
)
LY3023414 is an oral ATP competitive inhibitor of the class I PI3K isoforms, mTOR and
Lifitegrast
(Catalog# : 16071412, Cas# :
1025967-78-5
)
Lifitegrast, also known as SAR-1118, is an LFA-1 antagonist intended for the treatmen
Lonafarnib
(Catalog# : 16071008, Cas# :
193275-84-2
)
Lonafarnib is a farnesyl transferase inhibitor. Structurely, it is also a synthetic t
LJI308
(Catalog# : 16070904, Cas# :
1627709-94-7
)
LJI308 is a potent, and pan-RSK(p90 ribosomal S6 kinase) inhibitor withIC50of 6 nM, 4
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
--
Antibody-drug Conjugate/ADC Related
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
MGD-28
(Catalog# : 25073, Cas# :
2991818-13-2
)
MGD-28 is a potent molecular glue degrader that demonstrates significant in vitro eff
TG101209 analog 1
(Catalog# : 25072)
TG101209 analog 1 (Compound 8h) is an inhibitor of BUB1B with an IC50 of 10.36 μ M.
AT-007
(Catalog# : 25071, Cas# :
2170729-29-8
)
AT-007 is an orally active central nervous system (CNS) penetrant Aldose Reductase in
TAK-653
(Catalog# : 25070, Cas# :
1358751-06-0
)
TAK-653 is a novel AMPA receptor potentiator, strictly potentiating a glutamate-induc
Emavusertib
(Catalog# : 25069, Cas# :
1801344-14-8
)
Emavusertib, also known as CA-4948 is a potent IRAK4/FLT3 inhibitor with anti-tumor a
Roginolisib
(Catalog# : 25068, Cas# :
1305267-37-1
)
Roginolisib, also known as MSC2360844 and IOA-244, is a potent, orally active and sel
NT219
(Catalog# : 25067, Cas# :
1198078-60-2
)
NT219 is a novel inhibitor of the insulin/igf signaling cascade (iis), mediating a lo
SPB linker
(Catalog# : 25066, Cas# :
858128-57-1
)
SPB is a agent-linker conjugate for ADC with potent anti-inflammatory activity by usi
JTE-151
(Catalog# : 20594, Cas# :
1404380-58-0
)
JTE-151 is a novel RORγ inverse agonist.
Ecopipam ( SCH 39166 )
(Catalog# : 25065, Cas# :
112108-01-7
)
Ecopipam ( SCH 39166 ) is a Selective Dopamine Receptor D1/D5 Antagonist used in the